Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0004352 (
autism
)
32,579
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In this study, we evaluated the association between
autism
spectrum disorders (ASDs) and 10 single-nucleotide polymorphisms (SNPs) in the 5' region of the
semaphorin 5A
gene (
SEMA5A
) for 250 Korean trios including children with ASDs. Family-based association testing and haplotype analysis revealed a statistically significant association between rs194085 and multiple sociality traits with Korean ASDs in the dominant model (p<0.001, corrected p=0.035). This indicates that genetic variations in the 5' region of
SEMA5A
play a role in the genetic predisposition to sociality traits in Korean ASDs.
...
PMID:Polymorphism in the Promoter Region of
SEMA5A
Is Associated with Sociality Traits in Korean Subjects with Autism Spectrum Disorders. 2920 94
