Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Although there are associations linking autism with prenatal rubella, cytomegalovirus, syphilis, and varicella, the etiology of the autistic state remains obscure. Host defense against the etiologic agents postulated to be responsible for the autism-associated syndromes is believed to be primarily of the cell-mediated type. In this preliminary study, cellular immune function was assessed in vitro by phytohemagglutinin (PHA) stimulation of lymphocyte cultures. Twelve autistic children and 13 control subjects were compared. The autistic group exhibited a depressed lymphocyte transformation response to PHA when compared to the control subjects (p less than .01).
J Autism Child Schizophr 1977 Mar
PMID:Depressed lymphocyte responsiveness in autistic children. 13

Syphilis cases in the UK have risen from 301 in 1997 to 3,702 in 2006. After the autism scare of 1998, uptake of both doses of the MMR vaccine fell to 80 percent. Blackburn with Darwen PCT spent pound160,000 on vitamins after seeing a case of rickets every week.
 ...
PMID:Disease: a warning from history. 1853 14