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Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Records of the initial period of observation and the early history of 59 children with a diagnosis of childhood psychosis during the preschool years were examined for possible predictive variables. The children, now age 10 years or older, were divided into two groups--those that are presently successful and those that are presently unsuccessful, according to the criteria of this study. A cluster of 23 items was found significantly to differentiate the two groups.
J Autism Child Schizophr 1975 Dec
PMID:Prognostic antecedents and outcome in a follow-up study of children with a diagnosis of childhood psychosis. 124 36

Psychotic side effects of steroids have been observed at relatively high frequency if mild cases, such as euphoria, are included, while it has been said that incidences differ among kinds of steroids. We reported a case developing severe schizophrenia-like symptoms following the treatment with betamethasone although this drug is believed to be rarely involved in steroid-induced psychosis, and its psychotic side effects have been rarely reported. When betamethasone was administered for progressive peripheral facial paralysis at a mean daily dose of 7mg, psychotic symptoms appeared from the 15th treatment day. Psychosis began with interrupted appearance of excitation, autism, and misanthropia. Although the steroid was gradually decreased in dose because of abatement of facial paralysis, not only psychotic symptoms were aggravated, but also appeared hallucination. Thus the steroid was withdrawn before the scheduled date while its dose was gradually decreased, and haloperidol was administered. Psychotic symptoms were gradually eliminated and completely disappeared about 40 days after onset.
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PMID:[A case of steroid psychosis associated with betamethasone]. 128 92

Recent findings have suggested that the simultaneous occurrence of neurofibromatosis and childhood psychosis might be more than a coincidence. In this study of 341 children with infantile autism and other types of childhood psychosis seen as inpatients in two university clinics of child psychiatry in a 25-year period, only one case (0.3%) of concomitant occurrence of the disorders was found, which is a frequency no higher than expected by chance.
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PMID:Neurofibromatosis in infantile autism and other types of childhood psychoses. 131 Mar 63

At the present time, neuroleptics are indicated for the treatment of acute psychotic states as well as Tourette's syndrome in children and adults. Neuroleptics may have a useful role in the attenuation of problem behaviors, such as stereotypies, hyperactivity, self-injury, and aggressive outbursts in infantile autism, pervasive developmental disorder NOS, and mental retardation, but they do not improve the underlying condition. Neuroleptics are not the agents of first choice for treatment of hyperactivity or aggression in children who do not have major developmental handicaps. Common and troublesome side effects associated with neuroleptic use in children and adolescents include sedation, extrapyramidal symptoms, and withdrawal dyskinesias; therefore, close monitoring is required. Neuroleptics should be used cautiously and only as an adjunct to other nonpharmacologic interventions.
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PMID:Neuroleptics in pediatric psychiatry. 134 40

This paper highlights features of the work on autism of Tustin and others pertaining to the analysis of adult patients. Several clinical illustrations from the analysis of neurotic, borderline and psychotic patients emphasizing the survival function of autistic shapes, objects and delusions are presented. The need for further discrimination between autistic states of mind and other primitive mental states is recommended.
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PMID:On the survival function of autistic manoeuvres in adult patients. 139 87

The development of a theory of self-control of brain processes leads to a model of disturbance of integration of brain processes in psychotic persons. The theory is that the "novelty-familiarity relation" of the current state of the processed information normally dominates the current mode of information processing. In the second part of the study adults with schizophrenia in remission and children with infantile autism were tested as to the manner in which they used newly introduced elements. The psychotic persons took the different character of the new elements less into consideration. The difference from the normal control persons is significant.
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PMID:Self-organisation of cognitive processes and psychosis. Development and test of a theoretical model. 141 51

Early onset schizophrenia (EOS) is defined as that beginning in childhood or adolescence (under 16 or 17). Studies of EOS are infrequent, and comparative adult figures not always available, but tentative conclusions may be drawn. EOS is more common in males; symptomatology is often undifferentiated; frequencies of homotypic family disorder, premorbid schizotypal personality, and neurodevelopmental abnormalities high; outcome poor but only slightly worse than in adults; response to psychotropic drug treatment probably similar though not properly tested; and confusion with psychotic bipolar disorder particularly common. Onset before language is developed presents special diagnostic difficulties. There are a few reports of autistic children developing schizophrenia but this requires replication. Differences from adult schizophrenia are more marked when onset is in childhood than in adolescence but all are quantitative rather than qualitative suggesting that the disorders are the same and that there should be no separate category for children or adolescents.
J Autism Dev Disord 1992 Dec
PMID:Child and adolescent (early onset) schizophrenia: a review in light of DSM-III-R. 148 79

Three cases of fragile X (fra X) have been identified in a systematic survey of 30 boys, aged 3 to 14, with infantile autism or psychotic disorders, associated with mental retardation. Only one of these children exhibited a dysmorphy characterizing the Martin-Bell syndrome. Two fra X cases fulfilled the DSM III criteria for autism; none corresponded to the Kanner's description of infantile autism. The prevalence of fra X among children with psychotic disorders (6%) is much higher than in the general population; however it is close to the prevalence observed in non psychotic mentally retarded patients. Given the inconsistency of the somatic phenotype, the screening should benefit from the recent discovery of abnormal methylation of DNA.
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PMID:[Fragile X chromosome in autism and psychotic disorders in children]. 158 Jul 45

The authors report their own experiences of treatment with incisive neuroleptic drugs in child psychiatry (haloperidol, pimozide, penfluridol, sulpiride). An attention was paid to side effects of the treatment, especially to a possible side effect of cardiovascular character, namely that pimozide might block Ca channels. The authors made a control check of ECG and report the findings. The results of the treatment of various disorders (tic disorders, psychosis, obsessive- compulsive diseases, autism) are very good. The authors never came across the picture of serious side effects e.g. of tardive dyskinesis.
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PMID:Our experience with incisive neuroleptic drugs in child psychiatry. 168 49

We report the case of a boy whose development was normal until the age of three when regression with loss of speech occurred. Other anomalies included eating and sleep disorders, sterotyped behavior disorders, suggesting infantile psychosis. The electroencephalogram evidenced paroxysmal anomalies, particularly during sleep, with no clinical seizures. The diagnosis of epilepsia-acquired aphasia syndrome (Landau-Kleffner syndrome) was made. The psychotic disorders were not considered as a differential diagnosis but rather as intertwined with the elements of the syndrome. The relationship between acquired aphasia and psychosis are discussed.
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PMID:[Epilepsy-acquired aphasia syndrome with psychosis. Report of a case ]. 169 43


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