Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The life and work of the Zurich child and youth psychiatrist, Prof. Dr. med. J. Lutz, (25.1.1903 - 28.6.1998) is the subject of this report. It documents the outstanding achievements of Jakob Lutz as a doctor and scientist and tries to give a true portrayal of his impressive personality. A biographical part is dedicated to the personal and professional development of the son of a family of train drivers from Appenzell, who, after studying medicine in Zurich, became the founder of the child and youth psychiatric service in the Canton of Zurich. A detailed report is given on the formation of the child an youth psychiatric service in the Canton of Zurich over almost 40 years. It begins in 1929, when med. prakt. Jakob Lutz took over management of the Stephansburg, the first observation unit for child psychiatry in Switzerland, and ends in 1968, when he retired, after becoming Director of the service an both extraordinary professor and honorary professor for child an youth psychiatry. Discussions on different forms of therapy in child an youth psychiatry include ideas on the therapeutic activity of Jakob Lutz himself and his demands on the personality and training of therapist in child and youth psychiatry. The chapter on child schizophrenia, autism and mentally handicapped children deals with special patient groups. All the chapters report on the specific medical scientific work of Jakob Lutz, always supplemented with quotations from his personal statements. Finally, there is also a brief assessment of the successor in the service, Prof. Dr. med. J. Corboz, the first ordinary professor for child and youth psychiatry at the University of Zurich. A list of Jakob Lutz's publications, a list of the lecture titles, and time charts supplement the report.
 ...
PMID:[Dr. Jakob Lutz, life and work]. 1275 1

Diminished episodic memory and diminished use of semantic information to aid recall by individuals with autism spectrum disorder (ASD) are both thought to result from diminished relational binding of elements of complex stimuli. To test this hypothesis, we asked high-functioning adults with ASD and typical comparison participants to study grids in which some cells contained drawings of objects in non-canonical colours. Participants were told at study which features (colour, item, location) would be tested in a later memory test. In a second experiment, participants studied similar grids and were told that they would be tested on object-location or object-colour combinations. Recognition of combinations was significantly diminished in ASD, which survived covarying performance on the Color Trails Test (D'Elia et al. Color trails test. Professional manual. Psychological Assessment Resources, Lutz, 1996), a test of executive difficulties. The findings raise the possibility that medial temporal as well as frontal lobe processes are dysfunctional in ASD.
J Autism Dev Disord 2014 Sep
PMID:Binding of multiple features in memory by high-functioning adults with autism spectrum disorder. 2469 75