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Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A population-based survey was conducted among 152,732 Finnish children and adolescents aged under 16 years and living in northern Finland. Diagnoses and associated medical conditions were derived from the hospital and institutional records of this area. One hundred and eighty-seven children with DSM-IV autistic disorder were identified. Associated medical disorders or associated disorders of known or suspected genetic origin were found in 12.3 percent, including tuberous sclerosis, Down syndrome, fragile X syndrome, Klinefelter syndrome, XYY syndrome, chromosome 17 deletion, chromosome 46, XX, dup(8) (p) and mitochondriopathy. Other associated medical disorders identified were epilepsy, hydrocephalus, foetal alcohol syndrome and cerebral palsy. Hearing impairments were found in 8.6 percent and severe impairment of vision in 3.7 percent of the individuals with autistic disorder. Medical disorders seem to have a special impact on the genesis of autistic disorder and need to be thoroughly examined in each child with autistic disorder.
Autism 2004 Mar
PMID:Associated medical disorders and disabilities in children with autistic disorder: a population-based study. 1507 May 47

Two primary care practices were used to recruit adults with and without disability. Disability groups included autism, Down syndrome, cerebral palsy, and mental retardation. The patients without disability had an epilepsy prevalence rate of 1%. The prevalence of epilepsy within the disability groups was 13% for cerebral palsy, 13.6% for Down syndrome; 25.4% for autism, 25.5% for mental retardation, and 40% for adults with both cerebral palsy and mental retardation. During the decades of adulthood, the prevalence of epilepsy declined for those with cerebral palsy and mental retardation. The prevalence of epilepsy increased with advancing years for adults with Down syndrome, autism, and those without disability. Nonetheless, during each decade the prevalence of epilepsy was higher in all of the disability groups compared to those without disability.
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PMID:Prevalence of epilepsy in adults with mental retardation and related disabilities in primary care. 1556 66

Rett syndrome (RS), a neurological developmental disorder, is one of the commonest causes of cognitive impairment in girls and women. These patients are often initially misdiagnosed as idiopathic mental retardation, cerebral palsy, or autism. Despite several reports from the West, there are very few reports from the Indian population. We present four female children with RS and emphasize the importance of early diagnosis.
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PMID:Recent experience with Rett syndrome at a tertiary care center. 1562 43

Dousa-hou is a Japanese psychological rehabilitation method which is widely used in Japan for children with mental retardation, cerebral palsy, and autism. The primary focus of the rehabilitation method is to improve bodily movements and posture as well as to introduce social support to patients and their first-degree relatives. Analysis showed mothers got more social support interacting with their child's trainer and supervisor during Dousa-hou. Trainers were more interactive than mothers in the Indian group, followed by the Japanese and Korean cultural groups.
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PMID:Cross-cultural examination of social interactions during a one-week dousa-hou (Japanese psychorehabilitation) camp. 1566 54

A paediatric dietitian, occupational therapist and speech and language therapist describe how they jointly run a feeding clinic for infants and children with feeding difficulties. Conditions treated include cerebral palsy, autism, learned aversion following severe gastro-oesophageal reflux, and delayed oral development that affects feeding. The therapists' co-ordinated approach enables parents to receive clear guidance on feeding at one combined appointment, without the inconvenience of having to attend three separate appointments. The article outlines the role of each therapist, with examples of how they assess and alleviate the children's problems. The need for safety, nutrition and hydration is balanced against the desire for developmental progress in a holistic approach involving all three therapy disciplines. The aim of the feeding clinic is to provide advice, support and intervention plans to help make feeding a pleasurable and safe experience for all the children who attend.
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PMID:A multiprofessional children's feeding clinic. 1609

The purpose of this questionnaire survey is to gather information on actual conditions of inclusive child day-care in K City in order to qualify what support we can provide as part of the community. The questionnaire was sent to 148 child-care facilities (day nurseries) in date, of which 116 provided sufficient data for analysis. Of these 116 facilities, 104 (89.7%) accepted children with disabilities, while 12 (10.3%) did not. The number of disabled children accepted by the 104 facilities over a 2.5-year period was 275. Mental retardation (including children with multiple disabilities) was the most common type of disability; autism, physical disability and cerebral palsy were also seen. Thus, nursery staff, whose training is largely geared toward education and child development, is faced with a particularly difficult task. What we envisage as one of our future roles is to train and provide nursing experts with a specialized knowledge of medical rehabilitation, day-to-day medical care, training and support of children with various types of disabilities. Such nurses could then be introduced to child day-care facilities to provide individualized child-care services, which would take into account all factors relating to the child's condition and developmental stage. The results of our survey also suggest that close coordination and partnership with specialized/related agencies and institutions should be pursued in order to both enrich the support systems of child day-care facilities and to enhance their inclusiveness.
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PMID:[Actual condition survey on inclusive child day-care--a questionnaire survey of child day-care facilities in K city]. 1618 May 15

Developmental disabilities (DD) are defined as a diverse group of severe chronic conditions due to mental and/or physical impairments. Individuals with developmental disabilities have difficulty with major life activities including language, mobility, and learning. Developmental disabilities can begin anytime during development--from prenatal up to 22 years of age, and the disability usually lasts throughout a person's lifetime. Autism spectrum disorders, cerebral palsy, mental retardation, and attention deficit hyperactivity disorder are common conditions falling within the definition of developmental disabilities. Complementary and alternative medicine (CAM) is becoming increasingly utilized in the general population for treatment of everything from the common cold to complex and chronic medical conditions. This article reviews the prevalence of different types of CAM used for various developmental disabilities.
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PMID:Complementary and alternative medicine in developmental disabilities. 1639 50

Autism is a neurodevelopmental disorder that currently affects as many as 1 out of 166 children in the United States. Recent research has discovered that some autistic individuals have decreased cerebral perfusion, evidence of neuroinflammation, and increased markers of oxidative stress. Multiple independent single photon emission computed tomography (SPECT) and positron emission tomography (PET) research studies have revealed hypoperfusion to several areas of the autistic brain, most notably the temporal regions and areas specifically related to language comprehension and auditory processing. Several studies show that diminished blood flow to these areas correlates with many of the clinical features associated with autism including repetitive, self-stimulatory and stereotypical behaviors, and impairments in communication, sensory perception, and social interaction. Hyperbaric oxygen therapy (HBOT) has been used with clinical success in several cerebral hypoperfusion syndromes including cerebral palsy, fetal alcohol syndrome, closed head injury, and stroke. HBOT can compensate for decreased blood flow by increasing the oxygen content of plasma and body tissues and can even normalize oxygen levels in ischemic tissue. In addition, animal studies have shown that HBOT has potent anti-inflammatory effects and reduces oxidative stress. Furthermore, recent evidence demonstrates that HBOT mobilizes stem cells from human bone marrow, which may aid recovery in neurodegenerative diseases. Based upon these findings, it is hypothesized that HBOT will improve symptoms in autistic individuals. A retrospective case series is presented that supports this hypothesis.
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PMID:Hyperbaric oxygen therapy may improve symptoms in autistic children. 1655 23

An episode of hyperthermia is not uncommon during pregnancy. The consequences depend on the extent of temperature elevation, its duration, and the stage of development when it occurs. Mild exposures during the preimplantation period and more severe exposures during embryonic and fetal development often result in prenatal death and abortion. Hyperthermia also causes a wide range of structural and functional defects. The central nervous system (CNS) is most at risk probably because it cannot compensate for the loss of prospective neurons by additional divisions by the surviving neuroblasts and it remains at risk at stages throughout pre- and postnatal life. In experimental animals the most common defects are of the neural tube, microphthalmia, cataract, and micrencephaly, with associated functional and behavioral problems. Defects of craniofacial development including clefts, the axial and appendicular skeleton, the body wall, teeth, and heart are also commonly found. Nearly all these defects have been found in human epidemiological studies following maternal fever or hyperthermia during pregnancy. Suggested future human studies include problems of CNS function after exposure to influenza and fever, including mental retardation, schizophrenia, autism, and cerebral palsy.
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PMID:Review: Hyperthermia and fever during pregnancy. 1693 4

A 12-item Social Interaction Questionnaire was developed to measure the social interactions among trainers and mothers of children with disabilities in Dousa-hou camps. Dousa-hou is a Japanese psychological rehabilitation method which is widely used for children with mental retardation, cerebral palsy, and autism in Japan and other Asian countries. The primary focus of the rehabilitation method is to improve bodily movements, posture, and social support to patients and their first-degree relatives as well as promoting social interaction among participants. Two factors of interaction, (1) educational and daily life matters and (2) health and care matters, emerged through factor analysis. Cronbach coefficient alpha of the questionnaire was .91. The back-translated version of the Social Interaction Questionnaire also yielded two factors and Cronbach coefficient alpha of .87. It was found that mothers or first degree relatives (N=138; M = 43.5 yr., SD = 12.3) of the patients reported more social interaction than trainers when interacting with their child's trainer, supervisor, other trainers, and other mothers during six-day Dousa-hou camps.
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PMID:Development of a social interaction questionnaire for the trainers and mothers of children with disabilities participating in Dousa-hou (Japanese psycho-rehabilitation) camps. 1715 31


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