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Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)


J Autism Dev Disord 1979 Mar
PMID:Risks with controlling diet. 43 11

Peer-mediated social initiations and prompting/reinforcement procedures were evaluated (in training and generalization sessions) as interventions for increasing the positive social behavior of four autistic children. During baseline, the peer trainer made few social initiations and did not prompt or socially reinforce subjects. For two subjects, baseline was followed by social initiation intervention, and for the other two, baseline was followed by prompting and social reinforcement. Both interventions produced dramatic and comparable increases in positive social behavior in training sessions. Post-treatment responding was not observed for either intervention. When interventions terminated in a second baseline period, the subjects' behavior returned to the level observed during the initial baseline. The subjects were then exposed to the intervention procedure they had not yet experienced. Again, there were positive and comparable behavior changes in the treatment setting, but no increase in positive social behavior was observed during generalization assessment.
J Autism Dev Disord 1979 Mar
PMID:Effects of peer-mediated social initiations and prompting/reinforcement procedures on the social behavior of autistic children. 43 12

A 10-year-old boy first showed features of infantile autism at age 24 months. Histidinemia was also diagnosed, with histidine blood levels seven times higher than the upper normal values. If the coexistence of autism and histidinemia was not coincidental, histidinemia may have constituted a necessary but not sufficient factor leading to the clinical condition of autism. Other members of the patient's family had high blood levels of histidine, but did not show symptoms that have been related to histidinemia.
J Autism Dev Disord 1979 Mar
PMID:Histidinemia and infantile autism. 43 13

Children's free-play behavior and its relationship to IQ and usefulness in assessing severely disturbed children were investigated. The results indicated that (1) the play of 100 normal children scored for quality and time generally yielded significant positive correlations with Binet and WPPSI IQs; (2) the correlations remained the same when verbalizations were deleted from the play protocols; (3) the play scores for 16 severely disturbed boys significantly differentiated two subgroups differing in degree of pathology, showed significant improvement from the pre- to posttreatment periods, and indicated pretreatment scores were significantly and positively correlated with improvement assessed by observer ratings in a 2-year follow-up. Implications for the use of this measure in assessment and the role of play in development were discussed.
J Autism Dev Disord 1979 Mar
PMID:Free-play behavior of atypical children: an approach to assessment. 43 14

The recent upsurge in megavitamin therapy raises questions about the role of vitamin deficiencies and dependencies in mental health. With this in mind, the plasma levels of folic acid, ascorbic acid, pyridoxine, and riboflavin were studied in approximately 125 children admitted to a child psychiatric unit. There were no apparent decreased levels of vitamins in these children in terms of their age, race, or psychiatric diagnosis. It is postulated that vitamin deficiencies per se cannot be proposed as etiological factors in any of the psychiatric deficits represented. Megavitamin therapy, if successful, is not effective due to crrection of vitamin deficiencies as opposed to vitamin dependencies and may be due to the metabolic onus and consequent effects of such heavy doses of vitamins.
J Autism Dev Disord 1979 Mar
PMID:Plasma levels of folates, riboflavin, vitamin B6, and ascorbate in severely disturbed children. 43 15

This study investigated the effect of age on communication and maladaptive behavior in autistic and mentally retarded children. Forty-seven autistic and 128 mentally retarded children in a special school served as subjects. The cross-sectional method was used to compare junior and senior groups, and ratings on communication skills and maladaptive behaviors were obtained from teachers. We found that the skills of comprehension and conversation in autistic children improved significantly with age, and speech improved somewhat. In spite of this improvement in communication skills, maladaptive behaviors in the autistic children other than hyperactivity did not change significantly with age. Withdrawal improved significantly with age in the mentally retarded children but not in the autistic children.
J Autism Dev Disord 1979 Mar
PMID:Effects of age on communication skill levels and prevalence of maladaptive behaviors in autistic and mentally retarded children. 43 16

Patterns of parent-child interaction and family functioning were systematically examined in well-matched groups of 15 autistic and 14 dysphasic children. The measures used included the Douglas 24-hour standard day analysis, the Brown and Rutter interview measure of positive interaction, the Ittleson scales (based on a four- to six-hour period of home observation, specially developed time-sampled measures of observed mother-child interaction at home), and the Eysenck Personality Inventory. The findings from all measures agreed in showing that family life and interaction patterns were closely similar in the two groups. The results were compared with those of previous investigations; we concluded that autism is most unlikely to be due to abnormal psychogenic influences in the family.
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PMID:Families of autistic and dysphasic children. I. Family life and interaction patterns. 44 21

Recent research in childhood autism has provided support for the hypothesis that a central cognitive deficit involving severe language impairment underlies this disorder. In this study a group of autistic children were tested for handedness and for lateralization of speech function using a dichotic listening task. Contrary to earlier reports there were no left-handed children in the group although a number showed mixed preference. In the dischotic listening task using pairs of single syllable words the autistic group performed similarly to a matched group of normal children in terms of numbers of correct responses but over all did not show the right ear advantage characteristic of the normal children. There was a significant excess of right hemisphere dominance for verbal stimuli amongst the autistic children suggesting that for some at least, language functions had developed in the right hemisphere. Lateralization was shown to be related to presence or absence of speech before the age of 5 years and to IQ level.
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PMID:Hemisphere functioning in autistic children. 44 48

Hypothesized that the correlation between Inability to Abstract and Autism measures of schizophrenics would be larger after the effects of relevant personality variables were partialed out than before. The multiple correlations of these deficit measures with 15 of the Sixteen Personality Factor scales and a measure of verbosity were determined in a sample of 100 schizophrenics. The correlations between Inability to Abstract and Autism before and after those scales that contributed significantly to the Rs had been partialed out also were calculated. Neither was significant. The results offer no support for the view that observed differences between schizophrenic subgroups in inability to abstract and autism reflect variations in personality style rather than cognitive factors.
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PMID:The relationship of personality style to abstract thinking deficits in schizophrenia. 45 80

The authors compared a group of boys with childhood autism and a group of normal boys of similar age and found a decrease in urinary 3-methoxy-4-hydroxyphenethylene glycol (MHPG) in the autistic group. They hypothesize that autistic children might have an alteration in central and peripheral noradrenergic function, which might be related to impaired regulation of attention, arousal, and anxiety.
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PMID:Decreased 24-hour urinary MHPG in childhood autism. 46 31


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