Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0004153 (
atherosclerosis
)
77,401
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
4623
insulin
4540
HDL
3965
Mol
2826
cytokine
1898
C-reactive protein
1794
collagen
1549
apolipoprotein E
1535
LDL receptor
1408
apoE
1305
apolipoprotein
1210
tumor necrosis factor
1141
fibrinogen
1116
TNF
1060
vascular cell adhesion molecule-1
970
IL-6
941
apolipoprotein B
926
angiotensin II
807
vascular endothelium
768
Lp(a)
756
THP
752
renin
716
A-I
710
lipopolysaccharide
657
thrombin
655
nitric oxide synthase
649
adiponectin
638
interleukin-6
609
albumin
580
lipoprotein lipase
556
p38
551
chemokine
533
superoxide dismutase
525
CD36
521
adhesion molecule
519
HMG-CoA reductase
507
ICAM-1
499
Ang II
490
reductase
488
apolipoprotein A-I
487
CRP
481
matrix metalloproteinase
454
TNF-alpha
451
E-selectin
445
ATP
439
endothelial nitric oxide synthase
439
platelet-derived growth factor
435
hemoglobin
430
endoplasmic reticulum
430
MCP-1
424
intercellular adhesion molecule-1
422
elastin
410
ERK1
400
TLR4
397
MAPK
394
ABCA1
393
leptin
391
monocyte chemoattractant protein-1
385
IL-8
383
MRI
378
gut
378
von Willebrand factor
371
low-density lipoprotein receptor
361
peroxisome proliferator-activated receptor gamma
360
plasminogen activator inhibitor-1
358
endothelin-1
356
tissue factor
355
peroxisome proliferator-activated receptor
353
glycoprotein
353
cholesteryl ester transfer protein
352
LDLR
343
chronic renal failure
343
Pol
334
LPS
329
IL-10
328
p65
328
catalase
326
myeloperoxidase
323
P-selectin
309
HDL2
309
more...
Disease
atherosclerosis
77401
diabetes
8882
hypertension
8522
cardiovascular disease
7790
plaque
7364
coronary artery disease
5123
stroke
4424
myocardial infarction
4167
obesity
3967
coronary heart disease
3521
hypercholesterolemia
3269
cancer
2848
hyperlipidemia
2576
type 2 diabetes
2361
dyslipidemia
2083
vascular disease
2079
myocardial ischemia
1852
metabolic syndrome
1832
ischemia
1692
heart failure
1677
renal disease
1077
rheumatoid arthritis
1049
Alzheimer's disease
1032
hyperglycemia
959
acute myocardial infarction
919
systemic lupus erythematosus
790
heart disease
749
arteriosclerosis
709
tumor
690
Endothelial dysfunction
647
renal failure
580
osteoporosis
551
Chlamydia
550
atherosclerotic cardiovascular disease
517
hyperhomocysteinemia
514
arthritis
508
chronic renal failure
496
asthma
479
hyperinsulinemia
471
glucose intolerance
449
peripheral vascular disease
448
congestive heart failure
443
unstable angina
439
fatty liver
432
depression
423
ventricular hypertrophy
415
essential hypertension
412
dementia
377
vasculitis
373
cardiomyopathy
370
HIV
367
LDLR
343
lupus
338
hyperlipoproteinemia
327
HDL2
309
Plaque
294
abdominal aortic aneurysm
291
sepsis
291
cytomegalovirus
290
HDL3
288
infectious diseases
287
psoriasis
282
cerebral infarction
282
sepsis
280
cardiovascular risk factor
272
pulmonary hypertension
269
type 1 diabetes
259
intermittent claudication
259
retinopathy
246
malnutrition
245
transient ischemic attack
241
aortic stenosis
239
proteinuria
236
chronic disease
229
claudication
228
diabetic nephropathy
226
autoimmune disease
224
IMT
222
anemia
220
GSH
220
more...
Symptom
angina
1140
pain
384
overweight
345
chest pain
319
spasm
218
anesthesia
104
headache
90
abdominal pain
87
thinning
77
fatigue
77
weakness
70
dyspnea
62
seizures
53
starvation
52
collapse
50
diarrhea
47
exertional angina
41
exhaustion
40
hepatomegaly
38
discomfort
38
discomfort
38
vertigo
37
anorexia
35
flushing
34
dizziness
34
splenomegaly
33
hypothermia
32
syncope
32
ataxia
30
nausea
29
vomiting
28
respiratory distress
28
cachexia
27
leg pain
27
livedo
26
back pain
26
dystonia
25
myalgia
24
hemiplegia
23
dysarthria
22
functional recovery
21
sleepiness
21
regurgitation
21
constipation
19
hypercapnia
18
tinnitus
18
hepatosplenomegaly
17
menopausal symptoms
17
paresis
17
atypical chest pain
17
insomnia
17
acute stress
16
Stiffness
16
Depressive symptoms
14
snoring
14
cough
14
hyperoxia
14
HSA
13
analgesia
13
numbness
13
paresthesia
13
shortness of breath
12
memory loss
12
cyanosis
10
intestinal angina
9
exertional dyspnea
9
cerebellar ataxia
9
muscle cramps
9
colic
8
low back pain
8
lethargy
8
neck pain
8
abdominal discomfort
7
hemoptysis
7
hoarseness
7
hot flushes
7
epigastric pain
7
acute abdominal pain
7
acute abdomen
7
acidity
7
more...
Drug
Cardiovasc
2712
vitamin E
641
ascorbate
332
ROS
290
lysine
278
Angiotensin II
249
nitroglycerin
196
niacin
195
Dial
162
Monit
158
Simvastatin
151
Vitamin E
130
IFN-gamma
122
Dermatol
111
Pravastatin
103
MAP
97
CSF
91
EPA
82
IL-2
80
Nephron
77
Lovastatin
73
Rosuvastatin
69
ABC
67
NADH
64
Ezetimibe
63
Heme
62
Nephron
55
Gel
54
Estrogens
49
Clopidogrel
48
Kenyan
48
Gemfibrozil
47
BH4
43
EE2
42
ETA
41
Rosiglitazone
39
Bezafibrate
38
ROC
37
Indomethacin
36
Cilostazol
35
Clofibrate
34
Nitric Oxide
30
Albumin
29
caffeine
29
Asn
28
Histamine
28
Troglitazone
28
PTH
27
Glutathione
26
Captopril
26
Isradipine
25
Glucagon
25
Ethanol
24
Vitamin K
24
Leaf
21
ADM
21
ALA
20
ICI
20
Ramipril
20
CTA
20
uPA
19
Asthma
19
Vitamin A
19
Olive oil
19
CAM
19
Lacidipine
18
Lacidipine
18
Growth hormone
18
lactose
17
Growth hormone
17
Retinoic acid
16
Valsartan
16
p75
16
DNase I
16
THF
15
Tocopherol
15
pyridoxal phosphate
15
Vitamin B
15
CCL
14
ENT
14
more...
Enzyme
mitogen-activated protein kinase
1330
renin
716
thrombin
639
superoxide dismutase
629
lipoprotein lipase
561
NADPH oxidase
533
ERK
484
ACE
454
protein kinase
453
protein kinase C
451
peroxidase
429
NADPH oxidase
425
NO synthase
372
cholesterol acyltransferase
354
catalase
351
luciferase
345
lipase
338
phospholipase A2
314
tissue plasminogen activator
308
paraoxonase
275
glutathione peroxidase
266
paraoxonase
260
caspase-3
237
focal adhesion kinase
225
CAD
224
CAD
224
CAD
224
AMP-activated protein kinase
215
collagenase
213
lipoxygenase
167
lecithin:cholesterol acyltransferase
160
plasmin
148
alkaline phosphatase
145
APC
142
MEK
142
xanthine oxidase
139
3-hydroxy-3-methylglutaryl coenzyme A reductase
138
phosphodiesterase
133
elastase
133
lactate dehydrogenase
133
NOS
128
alanine aminotransferase
128
caspase-1
124
proteasome
118
AMPK
116
urokinase-type plasminogen activator
115
phosphatidylinositol 3-kinase
114
ACS
113
15-lipoxygenase
109
reverse transcriptase
109
ATPase
109
AMPK
105
thromboplastin
100
aspartate aminotransferase
97
trypsin
93
creatine kinase
93
methylenetetrahydrofolate reductase
92
methylenetetrahydrofolate reductase
92
LPL
85
cholesterol esterase
83
phospholipase C
80
heme oxygenase
79
guanylate cyclase
78
subtilisin
76
proprotein convertase
74
MMP-3
71
CYP7A1
70
MAP
70
MMP
68
furin
65
glutathione reductase
64
ACAT
63
arginase
63
calcineurin
61
chymase
56
phosphoinositide 3-kinase
56
PARP
54
ceruloplasmin
54
3-hydroxy-3-methylglutaryl-CoA reductase
53
glutathione S-transferase
52
more...
Compound
Dec
5203
Clin
4376
glucose
3540
oxygen
3198
Cardiol
3170
calcium
2530
nitric oxide
2331
DNA
2296
homocysteine
1120
TNF
1060
Cholesterol
949
water
819
arginine
804
THP
755
THP
752
sodium
746
acetate
716
copper
644
phosphate
633
Insulin
614
prostacyclin
574
creatinine
569
sulfate
508
iron
496
hydrogen
462
ATP
440
cysteine
421
tyrosine
392
ADP
385
methionine
368
lysine
346
Angiotensin II
337
ADP
311
nitrogen
307
ADP
305
aldosterone
301
Ang II
299
salt
286
ethanol
267
zinc
251
GSH
243
GSH
243
vitamin D
242
serine
241
cAMP
228
cGMP
221
nicotinic acid
215
H2O2
213
potassium
209
Homocysteine
208
Homocysteine
208
Estrogen
199
CoA
198
urea
196
leucine
190
ASA
187
NADPH
182
NADPH
182
CO2
174
nicotinic acid
171
Vitamin E
170
His
169
MTT
169
galactose
166
nitrate
166
nicotinamide
163
Estrogen
162
Dial
162
MDA
161
Atorvastatin
159
nicotinic acid
154
nicotinic acid
154
NAD
147
Oil Red O
134
selenium
133
N-acetylcysteine
131
AMP
126
aldehyde
126
Statin
123
NAD
122
more...