Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004153 (atherosclerosis)
77,401 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4623
insulin 4540
HDL 3965
Mol 2826
cytokine 1898
C-reactive protein 1794
collagen 1549
apolipoprotein E 1535
LDL receptor 1408
apoE 1305
apolipoprotein 1210
tumor necrosis factor 1141
fibrinogen 1116
TNF 1060
vascular cell adhesion molecule-1 970
IL-6 941
apolipoprotein B 926
angiotensin II 807
vascular endothelium 768
Lp(a) 756
THP 752
renin 716
A-I 710
lipopolysaccharide 657
thrombin 655
nitric oxide synthase 649
adiponectin 638
interleukin-6 609
albumin 580
lipoprotein lipase 556
p38 551
chemokine 533
superoxide dismutase 525
CD36 521
adhesion molecule 519
HMG-CoA reductase 507
ICAM-1 499
Ang II 490
reductase 488
apolipoprotein A-I 487
CRP 481
matrix metalloproteinase 454
TNF-alpha 451
E-selectin 445
ATP 439
endothelial nitric oxide synthase 439
platelet-derived growth factor 435
hemoglobin 430
endoplasmic reticulum 430
MCP-1 424
intercellular adhesion molecule-1 422
elastin 410
ERK1 400
TLR4 397
MAPK 394
ABCA1 393
leptin 391
monocyte chemoattractant protein-1 385
IL-8 383
MRI 378
gut 378
von Willebrand factor 371
low-density lipoprotein receptor 361
peroxisome proliferator-activated receptor gamma 360
plasminogen activator inhibitor-1 358
endothelin-1 356
tissue factor 355
peroxisome proliferator-activated receptor 353
glycoprotein 353
cholesteryl ester transfer protein 352
LDLR 343
chronic renal failure 343
Pol 334
LPS 329
IL-10 328
p65 328
catalase 326
myeloperoxidase 323
P-selectin 309
HDL2 309
more...
Disease
atherosclerosis 77401
diabetes 8882
hypertension 8522
cardiovascular disease 7790
plaque 7364
coronary artery disease 5123
stroke 4424
myocardial infarction 4167
obesity 3967
coronary heart disease 3521
hypercholesterolemia 3269
cancer 2848
hyperlipidemia 2576
type 2 diabetes 2361
dyslipidemia 2083
vascular disease 2079
myocardial ischemia 1852
metabolic syndrome 1832
ischemia 1692
heart failure 1677
renal disease 1077
rheumatoid arthritis 1049
Alzheimer's disease 1032
hyperglycemia 959
acute myocardial infarction 919
systemic lupus erythematosus 790
heart disease 749
arteriosclerosis 709
tumor 690
Endothelial dysfunction 647
renal failure 580
osteoporosis 551
Chlamydia 550
atherosclerotic cardiovascular disease 517
hyperhomocysteinemia 514
arthritis 508
chronic renal failure 496
asthma 479
hyperinsulinemia 471
glucose intolerance 449
peripheral vascular disease 448
congestive heart failure 443
unstable angina 439
fatty liver 432
depression 423
ventricular hypertrophy 415
essential hypertension 412
dementia 377
vasculitis 373
cardiomyopathy 370
HIV 367
LDLR 343
lupus 338
hyperlipoproteinemia 327
HDL2 309
Plaque 294
abdominal aortic aneurysm 291
sepsis 291
cytomegalovirus 290
HDL3 288
infectious diseases 287
psoriasis 282
cerebral infarction 282
sepsis 280
cardiovascular risk factor 272
pulmonary hypertension 269
type 1 diabetes 259
intermittent claudication 259
retinopathy 246
malnutrition 245
transient ischemic attack 241
aortic stenosis 239
proteinuria 236
chronic disease 229
claudication 228
diabetic nephropathy 226
autoimmune disease 224
IMT 222
anemia 220
GSH 220
more...
Symptom
angina 1140
pain 384
overweight 345
chest pain 319
spasm 218
anesthesia 104
headache 90
abdominal pain 87
thinning 77
fatigue 77
weakness 70
dyspnea 62
seizures 53
starvation 52
collapse 50
diarrhea 47
exertional angina 41
exhaustion 40
hepatomegaly 38
discomfort 38
discomfort 38
vertigo 37
anorexia 35
flushing 34
dizziness 34
splenomegaly 33
hypothermia 32
syncope 32
ataxia 30
nausea 29
vomiting 28
respiratory distress 28
cachexia 27
leg pain 27
livedo 26
back pain 26
dystonia 25
myalgia 24
hemiplegia 23
dysarthria 22
functional recovery 21
sleepiness 21
regurgitation 21
constipation 19
hypercapnia 18
tinnitus 18
hepatosplenomegaly 17
menopausal symptoms 17
paresis 17
atypical chest pain 17
insomnia 17
acute stress 16
Stiffness 16
Depressive symptoms 14
snoring 14
cough 14
hyperoxia 14
HSA 13
analgesia 13
numbness 13
paresthesia 13
shortness of breath 12
memory loss 12
cyanosis 10
intestinal angina 9
exertional dyspnea 9
cerebellar ataxia 9
muscle cramps 9
colic 8
low back pain 8
lethargy 8
neck pain 8
abdominal discomfort 7
hemoptysis 7
hoarseness 7
hot flushes 7
epigastric pain 7
acute abdominal pain 7
acute abdomen 7
acidity 7
more...
Drug
Cardiovasc 2712
vitamin E 641
ascorbate 332
ROS 290
lysine 278
Angiotensin II 249
nitroglycerin 196
niacin 195
Dial 162
Monit 158
Simvastatin 151
Vitamin E 130
IFN-gamma 122
Dermatol 111
Pravastatin 103
MAP 97
CSF 91
EPA 82
IL-2 80
Nephron 77
Lovastatin 73
Rosuvastatin 69
ABC 67
NADH 64
Ezetimibe 63
Heme 62
Nephron 55
Gel 54
Estrogens 49
Clopidogrel 48
Kenyan 48
Gemfibrozil 47
BH4 43
EE2 42
ETA 41
Rosiglitazone 39
Bezafibrate 38
ROC 37
Indomethacin 36
Cilostazol 35
Clofibrate 34
Nitric Oxide 30
Albumin 29
caffeine 29
Asn 28
Histamine 28
Troglitazone 28
PTH 27
Glutathione 26
Captopril 26
Isradipine 25
Glucagon 25
Ethanol 24
Vitamin K 24
Leaf 21
ADM 21
ALA 20
ICI 20
Ramipril 20
CTA 20
uPA 19
Asthma 19
Vitamin A 19
Olive oil 19
CAM 19
Lacidipine 18
Lacidipine 18
Growth hormone 18
lactose 17
Growth hormone 17
Retinoic acid 16
Valsartan 16
p75 16
DNase I 16
THF 15
Tocopherol 15
pyridoxal phosphate 15
Vitamin B 15
CCL 14
ENT 14
more...
Enzyme
mitogen-activated protein kinase 1330
renin 716
thrombin 639
superoxide dismutase 629
lipoprotein lipase 561
NADPH oxidase 533
ERK 484
ACE 454
protein kinase 453
protein kinase C 451
peroxidase 429
NADPH oxidase 425
NO synthase 372
cholesterol acyltransferase 354
catalase 351
luciferase 345
lipase 338
phospholipase A2 314
tissue plasminogen activator 308
paraoxonase 275
glutathione peroxidase 266
paraoxonase 260
caspase-3 237
focal adhesion kinase 225
CAD 224
CAD 224
CAD 224
AMP-activated protein kinase 215
collagenase 213
lipoxygenase 167
lecithin:cholesterol acyltransferase 160
plasmin 148
alkaline phosphatase 145
APC 142
MEK 142
xanthine oxidase 139
3-hydroxy-3-methylglutaryl coenzyme A reductase 138
phosphodiesterase 133
elastase 133
lactate dehydrogenase 133
NOS 128
alanine aminotransferase 128
caspase-1 124
proteasome 118
AMPK 116
urokinase-type plasminogen activator 115
phosphatidylinositol 3-kinase 114
ACS 113
15-lipoxygenase 109
reverse transcriptase 109
ATPase 109
AMPK 105
thromboplastin 100
aspartate aminotransferase 97
trypsin 93
creatine kinase 93
methylenetetrahydrofolate reductase 92
methylenetetrahydrofolate reductase 92
LPL 85
cholesterol esterase 83
phospholipase C 80
heme oxygenase 79
guanylate cyclase 78
subtilisin 76
proprotein convertase 74
MMP-3 71
CYP7A1 70
MAP 70
MMP 68
furin 65
glutathione reductase 64
ACAT 63
arginase 63
calcineurin 61
chymase 56
phosphoinositide 3-kinase 56
PARP 54
ceruloplasmin 54
3-hydroxy-3-methylglutaryl-CoA reductase 53
glutathione S-transferase 52
more...
Compound
Dec 5203
Clin 4376
glucose 3540
oxygen 3198
Cardiol 3170
calcium 2530
nitric oxide 2331
DNA 2296
homocysteine 1120
TNF 1060
Cholesterol 949
water 819
arginine 804
THP 755
THP 752
sodium 746
acetate 716
copper 644
phosphate 633
Insulin 614
prostacyclin 574
creatinine 569
sulfate 508
iron 496
hydrogen 462
ATP 440
cysteine 421
tyrosine 392
ADP 385
methionine 368
lysine 346
Angiotensin II 337
ADP 311
nitrogen 307
ADP 305
aldosterone 301
Ang II 299
salt 286
ethanol 267
zinc 251
GSH 243
GSH 243
vitamin D 242
serine 241
cAMP 228
cGMP 221
nicotinic acid 215
H2O2 213
potassium 209
Homocysteine 208
Homocysteine 208
Estrogen 199
CoA 198
urea 196
leucine 190
ASA 187
NADPH 182
NADPH 182
CO2 174
nicotinic acid 171
Vitamin E 170
His 169
MTT 169
galactose 166
nitrate 166
nicotinamide 163
Estrogen 162
Dial 162
MDA 161
Atorvastatin 159
nicotinic acid 154
nicotinic acid 154
NAD 147
Oil Red O 134
selenium 133
N-acetylcysteine 131
AMP 126
aldehyde 126
Statin 123
NAD 122
more...