Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004153 (atherosclerosis)
 77,401 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4623
insulin 4540
HDL 3965
Mol 2826
cytokine 1898
C-reactive protein 1794
collagen 1549
apolipoprotein E 1535
LDL receptor 1408
apoE 1305
apolipoprotein 1210
tumor necrosis factor 1141
fibrinogen 1116
TNF 1060
vascular cell adhesion molecule-1 970
IL-6 941
apolipoprotein B 926
angiotensin II 807
vascular endothelium 768
Lp(a) 756
THP 752
renin 716
A-I 710
lipopolysaccharide 657
thrombin 655
nitric oxide synthase 649
adiponectin 638
interleukin-6 609
albumin 580
lipoprotein lipase 556
p38 551
chemokine 533
superoxide dismutase 525
CD36 521
adhesion molecule 519
HMG-CoA reductase 507
ICAM-1 499
Ang II 490
reductase 488
apolipoprotein A-I 487
CRP 481
matrix metalloproteinase 454
TNF-alpha 451
E-selectin 445
ATP 439
endothelial nitric oxide synthase 439
platelet-derived growth factor 435
endoplasmic reticulum 430
hemoglobin 430
MCP-1 424
intercellular adhesion molecule-1 422
elastin 410
ERK1 400
TLR4 397
MAPK 394
ABCA1 393
leptin 391
monocyte chemoattractant protein-1 385
IL-8 383
MRI 378
gut 378
von Willebrand factor 371
low-density lipoprotein receptor 361
peroxisome proliferator-activated receptor gamma 360
plasminogen activator inhibitor-1 358
endothelin-1 356
tissue factor 355
peroxisome proliferator-activated receptor 353
glycoprotein 353
cholesteryl ester transfer protein 352
chronic renal failure 343
LDLR 343
Pol 334
LPS 329
IL-10 328
p65 328
catalase 326
myeloperoxidase 323
P-selectin 309
HDL2 309
ADP 305
PLA 304
MMP-9 303
vascular endothelial growth factor 300
caspase-3 295
ROS 290
IL-1 290
PDGF 287
JNK 285
ERK 284
plasminogen 272
CD4 270
nuclear receptor 263
inducible nitric oxide synthase 263
glutathione peroxidase 261
eNOS 261
p53 260
paraoxonase 258
hepatic lipase 257
Apolipoprotein E 252
Adiponectin 249
cyclooxygenase 245
fibronectin 244
Mal 244
calcium channel 243
membrane-bound 243
proprotein convertase subtilisin/kexin type 9 241
ACE 240
ABCG1 240
serum albumin 231
PI3K 229
A-II 226
CAD 224
GSH 220
cell adhesion molecule 217
apoB-100 217
plasminogen activator inhibitor 209
MMP-2 207
IFN 204
adipokine 203
Rho 203
CHD 202
bradykinin 198
LOX-1 191
PPAR 190
lectin 190
interferon 187
heme oxygenase-1 186
extracellular signal-regulated kinase 185
interferon-gamma 185
NADPH 182
tyrosine kinase 181
tumor necrosis factor alpha 179
CD68 178
proteoglycan 178
low density lipoprotein receptor 178
Bcl-2 176
CD40 176
phospholipase A2 174
AP-1 169
ATP-binding cassette transporter A1 169
cyclooxygenase-2 167
tissue plasminogen activator 167
lipoxygenase 164
Cytokine 164
mitogen-activated protein 164
mTOR 163
NLRP3 159
CD14 159
B12 157
COX-2 157
IL-18 155
PON1 155
SOD 154
metalloproteinase 153
histone 151
ATP-binding cassette 151
VEGF 150
osteopontin 149
CCL2 149
more...
Disease
atherosclerosis 77401
diabetes 8882
hypertension 8522
cardiovascular disease 7790
plaque 7364
coronary artery disease 5123
stroke 4424
myocardial infarction 4167
obesity 3967
coronary heart disease 3521
hypercholesterolemia 3269
cancer 2848
hyperlipidemia 2576
type 2 diabetes 2361
dyslipidemia 2083
vascular disease 2079
myocardial ischemia 1852
metabolic syndrome 1832
ischemia 1692
heart failure 1677
renal disease 1077
rheumatoid arthritis 1049
Alzheimer's disease 1032
hyperglycemia 959
acute myocardial infarction 919
systemic lupus erythematosus 790
heart disease 749
arteriosclerosis 709
tumor 690
Endothelial dysfunction 647
renal failure 580
osteoporosis 551
Chlamydia 550
atherosclerotic cardiovascular disease 517
hyperhomocysteinemia 514
arthritis 508
chronic renal failure 496
asthma 479
hyperinsulinemia 471
glucose intolerance 449
peripheral vascular disease 448
congestive heart failure 443
unstable angina 439
fatty liver 432
depression 423
ventricular hypertrophy 415
essential hypertension 412
dementia 377
vasculitis 373
cardiomyopathy 370
HIV 367
LDLR 343
lupus 338
hyperlipoproteinemia 327
HDL2 309
Plaque 294
abdominal aortic aneurysm 291
sepsis 291
cytomegalovirus 290
HDL3 288
infectious diseases 287
cerebral infarction 282
psoriasis 282
sepsis 280
cardiovascular risk factor 272
pulmonary hypertension 269
intermittent claudication 259
type 1 diabetes 259
retinopathy 246
malnutrition 245
transient ischemic attack 241
aortic stenosis 239
proteinuria 236
chronic disease 229
claudication 228
diabetic nephropathy 226
autoimmune disease 224
IMT 222
GSH 220
anemia 220
lupus 219
Familial hypercholesterolemia 218
uremia 218
aortic aneurysm 218
periodontitis 214
multiple sclerosis 214
renal artery stenosis 212
chronic obstructive pulmonary disease 203
dysplasia 201
abdominal obesity 200
antiphospholipid syndrome 200
renal insufficiency 194
microalbuminuria 194
cerebral ischemia 194
SEM 193
inflammatory bowel disease 192
obstructive sleep apnea 192
erectile dysfunction 191
cognitive impairment 190
neuropathy 183
carotid artery stenosis 181
periodontal disease 174
breast cancer 173
Peripheral arterial disease 171
hypothyroidism 170
hepatocellular carcinoma 170
carcinogenesis 164
AIDS 162
myocarditis 159
Parkinson's disease 155
glomerulosclerosis 155
cirrhosis 153
Lupus 146
cold 137
coronary thrombosis 137
osteoarthritis 137
liver disease 136
immunodeficiency 136
metabolic disorder 131
systemic disease 129
ATM 129
NAME 127
preeclampsia 127
Infection 127
aggression 126
nephrotic syndrome 125
pneumonia 121
tumor growth 121
arteriopathy 119
diabetic retinopathy 118
tumorigenesis 117
alcoholic fatty liver 115
Kawasaki disease 115
gangrene 115
genetic disorder 114
celiac disease 112
Adhesion 112
hyperuricemia 111
macular degeneration 108
SDS 106
carcinoma 105
polycystic ovary syndrome 104
gout 104
amyloidosis 104
SMC 103
lipid disorder 103
Nonalcoholic fatty liver 102
pancreatitis 99
tumor progression 98
xanthoma 96
sleep apnea 94
PSS 93
dilated cardiomyopathy 93
Tangier disease 91
carotid disease 90
psychological stress 89
subarachnoid hemorrhage 88
emphysema 87
virus infection 87
Carotid atherosclerosis 87
more...
Symptom
angina 1140
pain 384
overweight 345
chest pain 319
spasm 218
anesthesia 104
headache 90
abdominal pain 87
fatigue 77
thinning 77
weakness 70
dyspnea 62
seizures 53
starvation 52
collapse 50
diarrhea 47
exertional angina 41
exhaustion 40
discomfort 38
discomfort 38
hepatomegaly 38
vertigo 37
anorexia 35
dizziness 34
flushing 34
splenomegaly 33
syncope 32
hypothermia 32
ataxia 30
nausea 29
vomiting 28
respiratory distress 28
cachexia 27
leg pain 27
livedo 26
back pain 26
dystonia 25
myalgia 24
hemiplegia 23
dysarthria 22
functional recovery 21
regurgitation 21
sleepiness 21
constipation 19
tinnitus 18
hypercapnia 18
menopausal symptoms 17
paresis 17
hepatosplenomegaly 17
atypical chest pain 17
insomnia 17
acute stress 16
Stiffness 16
hyperoxia 14
snoring 14
cough 14
Depressive symptoms 14
analgesia 13
HSA 13
numbness 13
paresthesia 13
shortness of breath 12
memory loss 12
cyanosis 10
intestinal angina 9
exertional dyspnea 9
muscle cramps 9
cerebellar ataxia 9
colic 8
lethargy 8
low back pain 8
neck pain 8
hemoptysis 7
hoarseness 7
tremor 7
abdominal discomfort 7
acute abdominal pain 7
acidity 7
acute abdomen 7
flank pain 7
epigastric pain 7
leg edema 7
hot flushes 7
Spots 6
asthenia 6
arthralgia 6
spasticity 6
Decreased activity 6
pallor 6
Pulsatile tinnitus 6
blurred vision 6
DNA marker 5
dry eye 5
hot flashes 5
intestinal bleeding 5
emaciation 5
hypertonia 5
consciousness disturbance 5
Anoxia 5
nausea and vomiting 5
ophthalmoplegia 5
cardiovascular impairment 4
ENT 4
hunger 4
CSR 4
hypoproteinemia 4
left upper quadrant pain 4
cardialgia 4
hypotonia 4
hopelessness 4
eds 4
limb pain 4
apathy 4
Ill 4
polyuria 4
agitation 4
acute pain 4
Scratch 3
paraparesis 3
erythema 3
masculinization 3
wheezing 3
lightheadedness 3
polydipsia 3
decreased appetite 3
Hyperextension 3
skin damage 3
facial pain 3
corpulence 3
breath holding 3
Wind 3
Amaurosis fugax 3
oliguria 3
alexithymia 3
jaw pain 3
heartburn 3
rales 3
joint stiffness 3
forgetfulness 3
Stable angina pectoris 3
distraction 3
sore throat 3
sinus pressure 2
sneezing 2
dental pain 2
arm pain 2
Pain at rest 2
renal colic 2
syncopal episodes 2
Multimorbidity 2
Physical findings 2
chorea 2
hypocapnia 2
mastalgia 2
peri-menopausal 2
chronic back pain 2
precordial pain 2
presyncope 2
prostration 2
loin pain 2
more...
Drug
Cardiovasc 2712
vitamin E 641
ascorbate 332
ROS 290
lysine 278
Angiotensin II 249
nitroglycerin 196
niacin 195
Dial 162
Monit 158
Simvastatin 151
Vitamin E 130
IFN-gamma 122
Dermatol 111
Pravastatin 103
MAP 97
CSF 91
EPA 82
IL-2 80
Nephron 77
Lovastatin 73
Rosuvastatin 69
ABC 67
NADH 64
Ezetimibe 63
Heme 62
Nephron 55
Gel 54
Estrogens 49
Kenyan 48
Clopidogrel 48
Gemfibrozil 47
BH4 43
EE2 42
ETA 41
Rosiglitazone 39
Bezafibrate 38
ROC 37
Indomethacin 36
Cilostazol 35
Clofibrate 34
Nitric Oxide 30
Albumin 29
caffeine 29
Histamine 28
Asn 28
Troglitazone 28
PTH 27
Captopril 26
Glutathione 26
Glucagon 25
Isradipine 25
Ethanol 24
Vitamin K 24
Leaf 21
ADM 21
ALA 20
Ramipril 20
CTA 20
ICI 20
Olive oil 19
Vitamin A 19
Asthma 19
uPA 19
CAM 19
Growth hormone 18
Lacidipine 18
Lacidipine 18
lactose 17
Growth hormone 17
Retinoic acid 16
Valsartan 16
p75 16
DNase I 16
Tocopherol 15
pyridoxal phosphate 15
Vitamin B 15
THF 15
IL-1ra 14
ENT 14
GEO 14
CCL 14
TAK 13
CVA 13
G-CSF 13
Raloxifene 13
Perindopril 12
Bifidobacterium 12
Ciprofibrate 12
Fluorescein 12
Fructose 11
CTX 11
Norplant 11
Torcetrapib 11
Wine 11
Ginseng 11
Olmesartan 11
Gelatin 10
TAT 10
Vitamin B12 10
Iloprost 10
CaCl2 10
CaCl2 10
CaCl2 10
CS-514 10
Gliclazide 9
Colestipol 9
Lipitor 9
Lipitor 9
Darapladib 9
Lipitor 9
Emodin 9
Emodin 9
IL-11 9
Spectrum 9
MK-733 8
CPR 8
Palmitoyl 8
Paraffin 8
TAC 8
Sodium nitroprusside 8
Imatinib 8
Amlodipine besylate 8
citric acid 8
Adenosine triphosphate 8
Epigallocatechin 8
Orphan 8
DM1 8
Aminoguanidine 8
ampicillin 8
Norvasc 8
Forskolin 7
Aliskiren 7
FeCl3 7
Vinpocetine 7
Fragment 7
MRC 7
Olmesartan medoxomil 7
Niceritrol 7
Avasimibe 7
Serum albumin 7
Tranilast 7
Urokinase 7
Award 7
Nebivolol 7
EPI 6
NOV 6
Lescol 6
Orlistat 6
L-tyrosine 6
ETS 6
NAH 6
Everolimus 6
IFN-beta 6
linolenate 6
Trandolapril 5
Nilvadipine 5
Levonorgestrel 5
Parkin 5
Fluorescein 5
more...
Enzyme
mitogen-activated protein kinase 1330
renin 716
thrombin 639
superoxide dismutase 629
lipoprotein lipase 561
NADPH oxidase 533
ERK 484
ACE 454
protein kinase 453
protein kinase C 451
peroxidase 429
NADPH oxidase 425
NO synthase 372
cholesterol acyltransferase 354
catalase 351
luciferase 345
lipase 338
phospholipase A2 314
tissue plasminogen activator 308
paraoxonase 275
glutathione peroxidase 266
paraoxonase 260
caspase-3 237
focal adhesion kinase 225
CAD 224
CAD 224
CAD 224
AMP-activated protein kinase 215
collagenase 213
lipoxygenase 167
lecithin:cholesterol acyltransferase 160
plasmin 148
alkaline phosphatase 145
MEK 142
APC 142
xanthine oxidase 139
3-hydroxy-3-methylglutaryl coenzyme A reductase 138
phosphodiesterase 133
lactate dehydrogenase 133
elastase 133
NOS 128
alanine aminotransferase 128
caspase-1 124
proteasome 118
AMPK 116
urokinase-type plasminogen activator 115
phosphatidylinositol 3-kinase 114
ACS 113
reverse transcriptase 109
ATPase 109
15-lipoxygenase 109
AMPK 105
thromboplastin 100
aspartate aminotransferase 97
trypsin 93
creatine kinase 93
methylenetetrahydrofolate reductase 92
methylenetetrahydrofolate reductase 92
LPL 85
cholesterol esterase 83
phospholipase C 80
heme oxygenase 79
guanylate cyclase 78
subtilisin 76
proprotein convertase 74
MMP-3 71
MAP 70
CYP7A1 70
MMP 68
furin 65
glutathione reductase 64
arginase 63
ACAT 63
calcineurin 61
phosphoinositide 3-kinase 56
chymase 56
PARP 54
ceruloplasmin 54
3-hydroxy-3-methylglutaryl-CoA reductase 53
glutathione S-transferase 52
IKK 51
gamma-glutamyl transpeptidase 49
CYP27A1 49
beta-galactosidase 47
caspase-9 45
neuraminidase 44
hyaluronidase 43
cathepsin S 43
tryptase 42
matrix metalloproteinase 9 41
acid phosphatase 39
farnesyltransferase 37
cystathionine beta-synthase 37
RNase 37
RNase 37
RNA polymerase 36
aldose reductase 36
adenylate cyclase 36
matrix metalloproteinase 2 34
AST 34
hormone-sensitive lipase 33
endonuclease 33
glucose-6-phosphate dehydrogenase 32
CPT 32
PKG 31
kallikrein 31
neutrophil elastase 31
cdc2 30
lactonase 29
dimethylarginine dimethylaminohydrolase 29
caspase-8 29
endothelin-converting enzyme 28
DNA methyltransferase 28
12-lipoxygenase 28
heparinase 27
cathepsin B 27
MIP 27
lysyl oxidase 26
acetyl-CoA carboxylase 26
hyaluronidase 25
soluble epoxide hydrolase 25
phospholipase D 24
NQO1 23
beta-glucuronidase 23
GSK 23
acetylcholinesterase 23
CD10 23
PDE 22
aldehyde dehydrogenase 22
glyceraldehyde-3-phosphate dehydrogenase 21
cathepsin K 21
chondroitinase 20
diamine oxidase 20
CPT 20
cathepsin D 20
DCF 20
gamma-glutamylcysteine synthetase 19
myosin light chain kinase 19
acyl-CoA synthetase 19
papain 19
PTA 19
chondroitinase 18
alpha-glucosidase 18
cholinesterase 18
PAT 18
sialidase 18
CPT 17
lysozyme 17
methionine synthase 17
methionine synthase 17
peroxiredoxin 16
sphingosine kinase 16
histidine decarboxylase 16
indoleamine 2,3-dioxygenase 16
glyceraldehyde-3-phosphate dehydrogenase 16
prostacyclin synthase 16
diacylglycerol acyltransferase 16
interstitial collagenase 16
acyl-CoA synthetase 16
transglutaminase 15
more...
Compound
Dec 5203
Clin 4376
glucose 3540
oxygen 3198
Cardiol 3170
calcium 2530
nitric oxide 2331
DNA 2296
homocysteine 1120
TNF 1060
Cholesterol 949
water 819
arginine 804
THP 755
THP 752
sodium 746
acetate 716
copper 644
phosphate 633
Insulin 614
prostacyclin 574
creatinine 569
sulfate 508
iron 496
hydrogen 462
ATP 440
cysteine 421
tyrosine 392
ADP 385
methionine 368
lysine 346
Angiotensin II 337
ADP 311
nitrogen 307
ADP 305
aldosterone 301
Ang II 299
salt 286
ethanol 267
zinc 251
GSH 243
GSH 243
vitamin D 242
serine 241
cAMP 228
cGMP 221
nicotinic acid 215
H2O2 213
potassium 209
Homocysteine 208
Homocysteine 208
Estrogen 199
CoA 198
urea 196
leucine 190
ASA 187
NADPH 182
NADPH 182
CO2 174
nicotinic acid 171
Vitamin E 170
His 169
MTT 169
galactose 166
nitrate 166
nicotinamide 163
Dial 162
Estrogen 162
MDA 161
Atorvastatin 159
nicotinic acid 154
nicotinic acid 154
NAD 147
Oil Red O 134
selenium 133
N-acetylcysteine 131
aldehyde 126
AMP 126
Statin 123
NAD 122
Probucol 122
Fibrinogen 114
Oil Red O 114
ACS 113
PMA 112
threonine 111
ACS 111
alanine 111
Thrombin 109
iodine 108
tryptophan 108
phosphorus 108
DHA 107
SDS 107
chromate 105
Diabetol 104
aldehyde 103
noradrenaline 102
tryptophan 101
silver 101
PEG 99
tryptophan 98
tryptophan 98
Resveratrol 97
HMG-CoA 97
Pravastatin 95
Diabetol 95
Asp 94
PLA 93
hyaluronic acid 92
5-HT 90
superoxide radical 89
palmitic acid 88
ACh 86
MAP 86
glycerol 85
Collagen 83
EDTA 83
Ascorbic acid 82
Phe 82
H2S 82
proline 81
EDTA 80
EPA 80
Curcumin 79
Optimal 78
palmitic acid 77
Gly 77
Pac 77
PGE2 75
bromide 74
PMA 72
Heparin 71
NH2 71
Vitamin D 70
Sudan IV 69
MEK 69
retinoic acid 68
PGE 68
retinol 67
hydroxide 66
glutamine 65
Heme 64
Metformin 64
DHA 63
Metformin 63
NADH 63
pyrrolidine 63
dUTP 63
DHA 62
AGE 61
Nicotine 61
Mg2+ 60
Fenofibrate 60
cadmium 60
2-nonenal 57
prostaglandin E1 57
pyrrolidine 57
Thyroid 55
manganese 55
more...