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Query: UMLS:C0004153 (atherosclerosis)
 77,401 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 50 patients with transient disorders of cerebral circulation due to hypertensive disease (27 cases), and combinations of hypertensive disease with atherosclerosis (23 cases) the authors by means of diluting Ewans blue stain (T-1824) studied the indices of general hemodynamics compared to that of REG data . For control purposes 10 patients with hypertensive disease in concomitance with atherosclerosis without transient disorders of cerebral circulation and 20 normals were studied. The study permitted to detect signs of disturbed general and cerebral hemodynamics which were most expressed in patients with severe cerebro-vascular crises, accompanied by a drop in the cardiac and pulse index, an increase of the general and specific peripheral resistance, a slowing of the blood flow rate on the segment hand-ear, an increase of the tone and drop of elasticity in the cerebral vessels, a decrease of cerebral blood repletion. Insufficiency of general hemodynamics leads to disorders of cerebral hemodynamics and unfavourably influences the development of the disease and the outcome of cerebrovascular crises.
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PMID:[State of systemic and cerebral hemodynamics in patients with transient cerebral circulatory disorders]. 36 13

Fifty patients with the clinical diagnosis of initial manifestations of the deficiency of the brain blood supply and 30 normal persons of the corresponding age (the control group) were studied. The main group consisted of patients from 40-67 years. Along with the similar clinical study rheoencephalographic and electroencephalographic studies with the aid of various functional samples were conducted. The initial manifestations of the inadequacy in the brain blood supply frequently developed on the background of cerebral atherosclerosis of a different type of expressiveness, hypertensive disease and their combination, vegetovascular dystonia. With the help of the functional samples the peculiarities of reactivity of the vascular system were established in these patients. The antiorthostatic and nitroglycerin samples appeared to be informative. The combined REG and EEG registrations demonstrated in these patients signs of a deficit of brain blood supply causing in a number of cases changes in its functional states. The clinical (seldom electrographic) changes are of a reversible character and regress during the treatment of the main vascular disease. The obtained data permit to recommend the method of functional electrography (REG and EEG) in order to reveal the initial forms of brain vascular diseases. These patients must be supervised by a dispansary.
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PMID:[Initial manifestations of cerebrovascular insufficiency (clinico-electrographic studies)]. 41 95

The authors studied general and cerebral hemodynamics in 51 patients with cerebral atherosclerosis transient disorders of cerebral circulation. The studies demonstrated correlation between the indices of general peripheral resistance of the blood flow, cardiac and pulse indices. The rate of the blood flow in the segment hand-ear was slower. REG studies detected deficit of blood repletion, intrahemispheric asymmetry, a drop in the elasticity of the vascular wall. These data may be used in prescribing pathogenetical treatment to patients with transient disorders of cerebral circulation.
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PMID:[General and cerebral hemodynamics in atherosclerosis of the cerebral vessels with transient disorders of cerebral circulation]. 62 49

The presentation contains the result of a rheoencephalographic study of 67 sons and daughters of the patients with ischemic stroke of a hemispheric localization. Some rheoencephalographic signs testifying to the presence of a cerebro-vascular deficiency in the relatives of the probands were depicted. The use of nitroglycerin sample permitted to reveal in practically healthy relatives certain REG changes which exceeded the normal limits. These shifts were mainly observed in the elder age group of the investigated individuals (above 40 years). The obtained data can promote detection of those individuals who are predisposed to atherosclerosis and hypertensive disease, and to conduct medico-prophylactic measures in due time.
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PMID:[A rheoencephalographic study of the relatives of patients with acute cerebral circulatory disorders]. 81 61

With the aid of a REG method the authors studied the effect of dexametasone on the cerebral hemodynamics in 37 patients with cerebral atherosclerosis with chronic cerebrovascular insufficiency. It was possible to show that there is an accelerated venous blood outflow, a decreased vascular resistance, as well as the absence of a vasopressor reaction to a single intravenous administration of 4 mg of dexametasone. The capability of the preparation to reduce the volume of cerebral pulse waves limits its use in the initial decreased amplitude of cerebral pulse fluctuations.
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PMID:[Effect of dexamethasone on indices of cerebral circulation]. 101 11

On the basis of modern knowledge of the clinical picture, pathophysiology and pathomorphology of the residual period of brain injuries and a study of 140 cases, examined in the Central Institute for Expertise of Working Capacity the author discusses some clinical characteristic of the remote sequelae of brain injuries received during the war and the possible variants of their pathogenesis. A comprehensive clinical study of such patients with the use of paraclinical methods (EEG, REG) permitted to establish a cerebro-vascular nature of these disorders with a development of vasopathy, traumatical hypertension, early vascular involution with a transition to early cerebral atherosclerosis. Having this in view the author considers some problems of the causal connections of these disorders with injuries and concussions received at war.
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PMID:[Progressive course of the sequelae of closed cranio-cerebral trauma at remote periods (in relation to the test of rehabilitating invalids from the Second World War)]. 101 41

The authors describe clinical manifestations of pseudoneurotic states and vegetative paroxysms in 78 patients with transient disturbances of brain circulation which appeared due to hypertensive disease and atherosclerosis. The special studies (EEG, REG, determination of catecholamine excretion) showed that pseudoneurotic states and paroxysmal vegetative disturbances depend on the state of brain circulation and functional activity of the sympathetico-adrenal system. The authors attempt to differentiate pseudoneurotic and paroxysmal vegetative disorders in transient disturbances of brain circulation from neuroses and initial dysfunction of the vegetative structures.
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PMID:[Pseudoneurotic states in patients with transient cerebral circulatory disorders]. 121 3

The authors investigated the diagnosis and treatment of the initial forms of venous encephalopathy in atherosclerosis in 42 patients, using synchronous rheoencephalography and jugular rheophlebography under conditions of graded exercise on a bicycle ergometer. The study revealed signs of venous encephalopathy with dystonic, asthenovegetative, psychopathological, pseudotumorous and other syndromes which were confirmed by changes in the parameters of the REG, rheophlebogram, etc. Graded exercise in a compensated phase of the disease led to a reduction in signs of venous congestion in the brain, while in a subcompensated phase these signs increased. The effect of a multiple modality treatment with due regard to the phase of compensation and the leading syndrome was good or satisfactory in the majority of patients.
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PMID:[Diagnosis and pathogenetic treatment of venous encephalopathy in early atherosclerosis]. 377 16

Clinical and polygraphical (EEG, EOG, EMG, ECG, REG) studies of nocturnal sleep and of the hemodynamics were carried out in 60 patients with dyscirculatory encephalopathy induced by hypertension and atherosclerosis. The findings obtained demonstrate that the clinical picture in these patients is always characterized by sleep disturbances which decrease the level of their diurnal wakefulness and their capacity for work. Hemodynamic disturbances responsible for sleep disorders are in turn maintained by the latter which leads to the formation of the vicious circle. This is also supported by the fact that compromized cerebral circulation causes changes in the activity of the structures involved both in sleep-wakefulness function and the regulation of the cerebral and systemic hemodynamics. Hence, deviations in the nocturnal sleep pattern attended with pronounced alterations in the cerebral hemodynamics may contribute to the development of acute disorders of the cerebral circulation. The authors recommend correcting not only the disrupted structure of sleep but also the cerebral circulation with relation to he sleep-wakefulness cycle.
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PMID:[Nocturnal sleep and cerebral hemodynamics in different sleep stages and cycles among patients with early manifestations of cerebral circulatory insufficiency]. 650 76

A combined study of the function of the central nervous system was carried out in 250 young and middle-aged patients (40-59 years) presenting initial clinical manifestations of cerebral vascular atherosclerosis. The age of the subjects allowed the authors to conditionally refer them to a group of patients with early cerebral atherosclerosis (ECA). The cerebral bloodflow was studied by examining such parameters as 133Xe clearance, functional REG, EEG, orientation reaction and visual evoked potentials: the findings obtained made it possible to specify the role of hemodynamic disorders in the formation of neurologic defect at this stage of the disease. The data presented point to a considerable acceleration of the aging process in patients with ECA, i.e., the so-called premature aging, manifested in the fact that such patients appear to be 10-15 years older than their age as judged by many age parameters. The authors recommend wider application of functional methods for the examination of the nervous system and hemodynamics aimed at determining the orientation and tactics of therapeutic and prophylactic measures with a view of preventing the progression and complications of the disease.
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PMID:[Clinico-physiologic features of the initial manifestations of incomplete blood-filling of the cerebral circulation in young and middle-age cerebral atherosclerosis patients]. 662 36


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