Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0004153 (atherosclerosis)
 77,401 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Fifty patients with the clinical diagnosis of initial manifestations of the deficiency of the brain blood supply and 30 normal persons of the corresponding age (the control group) were studied. The main group consisted of patients from 40-67 years. Along with the similar clinical study rheoencephalographic and electroencephalographic studies with the aid of various functional samples were conducted. The initial manifestations of the inadequacy in the brain blood supply frequently developed on the background of cerebral atherosclerosis of a different type of expressiveness, hypertensive disease and their combination, vegetovascular dystonia. With the help of the functional samples the peculiarities of reactivity of the vascular system were established in these patients. The antiorthostatic and nitroglycerin samples appeared to be informative. The combined REG and EEG registrations demonstrated in these patients signs of a deficit of brain blood supply causing in a number of cases changes in its functional states. The clinical (seldom electrographic) changes are of a reversible character and regress during the treatment of the main vascular disease. The obtained data permit to recommend the method of functional electrography (REG and EEG) in order to reveal the initial forms of brain vascular diseases. These patients must be supervised by a dispansary.
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PMID:[Initial manifestations of cerebrovascular insufficiency (clinico-electrographic studies)]. 41 95

Coagulation and rheological, cerebrovascular and total hemodynamic factors were studied and compared in patients with the initial manifestations of brain blood supply insufficiency (IMBBSI) associated with vegetovascular dystonia, essential hypertension and atherosclerosis by means of factor analysis. Interrelations between the parameters under study appeared multiple in nature, possessing a high capacity for differentiation between those conditions. As IMBBSI progressed, namely from vegetovascular dystonia to the hypertonic and atherosclerotic disease forms, there was a rise in the rate of the prognostically unfavourable ++inter-systemic relations between hemostasis and hemodynamics attesting to a certain risk of cerebral ischemias.
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PMID:[Factor analysis of the coagulative-rheological properties of blood and plasma and cerebral and general hemodynamics in patients with the initial forms of cerebrovascular insufficiency]. 164 1

The examination was performed of 80 patients exhibiting initial signs of defective cerebral circulation in the presence of cerebral atherosclerosis, cervical osteochondrosis, vascular dystonia. Clinical and rheoencephalographic evaluation of the patients treatment by application of peloids in combination with electrophoresis of vasoactive drugs (cavinton and trental) allowed a differential approach to assignment of the above modalities.
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PMID:[Cerebral hemodynamic function in patients with the initial manifestations of brain blood supply failure under the influence of pelotherapy combined with the electrophoresis of vasoactive preparations]. 179 18

Altogether 94 patients with initial manifestations of brain blood supply failure (IMBBSF) consequent on vegetative vascular dystonia and atherosclerosis of the cerebral vessels were examined. Clinical, echopulsographic and dopplerographic examinations demonstrated that 54 patients had cerebral venous discirculation. The main diagnostic criteria for cerebral venous discirculation in patients with IMBBSF lie in an increase of the configuration of the diastolic part of the echoPG of the cerebral arteries, possibility of recording echoPG of the cerebral veins, a rise of the linear velocity of the blood flow in the jugular veins under head-down test during dopplerography.
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PMID:[Diagnostic criteria of ultrasonographic methods of the study of cerebral venous circulatory failure in initial manifestations of cerebrovascular disorders]. 217 94

The authors studied the indices of general hemodynamics in 53 patients with initial manifestations of cerebro-circulatory insufficiency of young and middle age. Young patients suffering of cerebral atherosclerosis and vegetative-vascular dystonia showed a hyperkinetic type of hemodynamics while the middle-aged with atherosclerosis showed the hypokinetic type evidencing abnormal function of autoregulatory mechanisms.
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PMID:[Central hemodynamics in young and middle-aged patients with the initial manifestations of cerebral circulatory failure]. 223 1

Noncontact biomicroscopy has been carried out in 107 women, aged 20-57, with the initial symptoms of inadequate blood supply to the brain in the presence of vegetovascular dystonia, arterial hypertension, and cerebral atherosclerosis in order to examine the end blood flow in such abnormalities. The findings evidence a universal pattern of changes in the microvessels in any of the vascular diseases; the severity of these shifts depends on the disease severity and length. Persistent red cell aggregation in the venules of patients with cerebral atherosclerosis is a critical sign predicting the process progressing. Hypercholesterolemia correlates with the severity of intravascular and vascular shifts.
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PMID:[Microcirculatory disorders in the system of conjunctival vessels in initial manifestations of inadequate blood supply to the brain]. 272 64

A study of 70 teenagers between 11 and 15, whose parents had suffered, before they were 45, myocardial infarction in the presence of verified coronary arterial atherosclerosis, revealed no organic cardiac changes, while some signs of neurocirculatory dystonia were combined with increased incidence of coronary risk factors and dyslipoproteinemia.
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PMID:[Functional status of the cardiovascular system of adolescents with a hereditary predisposition to atherosclerosis]. 295 50

Regional and central circulation reactions to 30-day antiorthostatic hypokinesia were investigated in 15 men, aged 45 to 52 years, with early signs of cerebrovascular and aortic atherosclerosis, neurocirculatory dystonia of the hypertensive type, and hypertensive disease of stage I. Regional and central hemodynamics of the subjects of the three groups during and immediately after exposure developed in a different manner.
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PMID:[Reaction of blood circulation to antiorthostatic hypokinesia in men aged 45-52]. 365 61

An assessment of one-feature and combined diagnostic value of plasma lipid and apolipoprotein parameters, using stepwise discriminant analysis, was designed to make possible correct differentiation between coronary heart disease (CHD) due to angiographically-verified coronary atherosclerosis and neurocirculatory dystonia (NCD) without signs of coronary arterial affection. The apolipoprotein B/apolipoprotein AI (apo B/apo AI) ratio was shown to be the best single apolipoprotein marker capable of correct differentiation between CHD and NCD in 74% of cases. It was similar to the best lipid diagnostic marker, the cholesterol atherogenic index, in terms of discriminating power. The combination of the apo B/apo AI ratio + age + systolic arterial blood pressure proved to be the best combined indicator, bringing the diagnostic error down to 18%.
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PMID:[Blood plasma lipids and apolipoproteins as indicators of coronary atherosclerosis]. 376 24

The authors studied the parameters of the central and cerebral hemodynamics in 66 males aged 38-58 years who were treated at a health resort for initial manifestations of cerebral circulation insufficiency (CCI). A test with graded exercise (GE) revealed in all patients an increase in the total peripheral vascular resistance (TPVR) which was the greatest in cases of initial manifestations of CCI due to borderline arterial hypertension (AH). In the period of recovery and following the nitroglycerin test the TPVR returned to the initial level in patients with AH and vegetovascular dystonia whereas there was no such decrease in patients with initial cerebral atherosclerosis. Already at the 1st minute of the recovery period following GE patients with atherosclerosis (A) and essential hypertension (EH) presented a considerable increase in the arterial tone (AT) which remained stable even after 10 min of rest. These changes in AT indicated a decrease in the adaptational possibilities of the cerebral hemodynamics and simultaneously made it possible to differentiate them from vegetovascular dystonia when AT increased insignificantly only during the first min after GE and then rapidly returned to the initial level and diminished even more during the nitroglycerin test. The proposed method of comprehensive examination of parameters of the central and cerebral hemodynamics when combined with neuropsychological findings makes it possible not only to improve the diagnosis of diseases responsible for initial manifestations of CCI but also to considerably increase the objectivity of the assessment of the sanatorium treatment.
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PMID:[Diagnosis and sanatorium treatment of the initial manifestations of inadequate blood supply to the brain]. 377 9


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