Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004153 (atherosclerosis)
 77,401 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tenascin is a protein family in the extra cellular matrix (ECM) that consists of four members: tenascin C, tenascin R, tenascin X, and tenascin W. Among the four tenascins, tenascin-C was the first identified and have been the most studied member of the family. In 2006, a patent was registered for a formula containing tenascin C, and the formula has been claimed to be beneficial in treating and preventing vascular diseases such as atherosclerosis. Therefore, this review discusses the structure of tenascin C molecule, its various functions, the possibility of imaging tenascin C expression for diagnosis, the prospect of tenascin C in the therapy of atherosclerosis, and suggestions for further research. This review discusses the structure of tenascin C molecule, its various functions, the potential of imaging tenascin C expression for diagnosis, weighing the prospect of using tenascin C in the therapy of atherosclerosis, and future research suggestions.
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PMID:Weighting the potential of using tenascin C in diagnosis and therapy of atherosclerosis. 2051 36