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Query: UMLS:C0004153 (atherosclerosis)
 77,401 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

True aneurysm of the subclavian artery is extremely rare. Excluding the more common aneurysms of an aberrant right subclavian artery, those associated with thoracic outlet syndrome, and posttraumatic "aneurysms," atherosclerosis is the most common cause. Syphilis, tuberculosis, and cystic medial necrosis are less often the cause. These aneurysms can rupture, thrombose, embolize, or cause symptoms by local compression. Surgical treatment is generally indicated, and has evolved from ligation procedures to extirpation or endoaneurysmorrhaphy to the present practice of resection with revascularization. A case of a surgically treated, asymptomatic, atherosclerotic aneurysm of the intrathoracic left subclavian artery is presented, with a review of the English-language literature on the subject.
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PMID:Atherosclerotic aneurysm of the intrathoracic subclavian artery: a case report and review of the literature. 787 37

One hundred and twenty cases of stroke occurring in Saudi Arabian subjects aged 15 to 45 years are reviewed. These constituted 12.7% of a group of 946 stroke patients. Males outnumbered females (76/44). The frequency of intracranial hemorrhage, including subarachnoid hemorrhage, was slightly lower than cerebral infarction (41.5 vs 58.5%). The causes of large cerebral infarction were as follows: atherosclerosis 17 (28%), cardiac embolism 12 (19.5%), uncommon and uncertain causes 21 (34.5%). Some unusual causes were encountered such as dissecting arterial aneurysm due to popular healing manoeuvres or to traditional dance, retrograde embolism from a thoracic outlet syndrome or embolism from a fibroelastoma of the mitral valve chorda. Lacunar cerebral infarction was diagnosed in nine cases. Hypertension (25.5%) and arteriovenous malformations (20.5%) were the main causes of cerebral hemorrhage; all subarachnoid hemorrhages except one were due to berry aneurysms. The cause was undetermined in 16% of cerebral infarction and 26% of intracranial hemorrhage. The high frequency of stroke in young Saudi Arabian adults is probably a reflection of the demographic structure of the predominantly young Saudi society. The observed causes were relatively similar to those in industrial societies. Contrary to other developing countries infectious disease no longer seems to be an important cause of stroke. Drug abuse, which is becoming an important cause in Western societies, was encountered in only two of our cases.
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PMID:Stroke in Saudi Arabian young adults: a study of 120 cases. 808 29

We report the management of 14 subclavian artery aneurysms (13 true, one false) occurring in seven male and seven female patients (average age, 48 years). The aetiology of the aneurysms included thoracic outlet syndrome in eight, atherosclerosis in five and infection in one patient. Twelve aneurysms were of extrathoracic location, while two aneurysms were intrathoracic. Symptoms related to subclavian artery aneurysms were present in 11 patients (compression in four, haemorrhage in one, and ischaemia in six patients), whereas three aneurysms were asymptomatic. All aneurysms were treated surgically. The supraclavicular approach was used in 11 cases, and the combined transsternal and supraclavicular approach was used in two cases. After aneurysm resection, the reconstruction was performed with end-to-end anastomosis in five cases and with saphenous vein or synthetic grafts in eight cases. One infected subclavian artery aneurysm was treated with carotid to axillary saphenous vein bypass after exclusion of the aneurysm. Five associated brachial embolectomies and one bypass from the axillary to the distal brachial artery were performed. In all thoracic outlet syndrome cases, decompression at the thoracic outlet was also performed. There was no operative mortality, and the early patency rate was 100%. The follow-up period was from 6 months to 10 years (mean, 3.92 years). During this period, one patient died of malignancy and one patient required reoperation due to aneurysmal degeneration of the saphenous vein graft. Surgical treatment is recommended for all patients with subclavian artery aneurysms to prevent potential complications.
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PMID:Subclavian artery aneurysms. 1252 87

Subclavian artery occlusive disease is usually secondary to persistent compression caused by thoracic outlet syndrome (TOS) and rarely due to focal atherosclerosis. Emboli from diseased vessel can flow retrograde to the vertebral or carotid arteries to produce ischemic infarct with or without neurological deficit. We are reporting two cases of distal subclavian artery disease presenting with cerebral embolization, an unusual manifestation. Such surgically correctable lesions producing cerebral emboli and stroke needs consideration while evaluating patients with unusual presentation to prevent further occurrence of stroke.
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PMID:Cerebral embolism: distal subclavian disease as a rare etiology. 1671 43

We reviewed the role of contrast magnetic resonance angiography (MRA) in patients with vascular disorders of the upper extremity. MRA accurately defines stenoocclusive lesions in patients with atherosclerosis and embolus. It helps to diagnose thoracic outlet syndrome, vascular malformations, and vasculitis. It demonstrates vascular injuries after blunt or occupational trauma, corkscrew collaterals in Burger's disease, and pathological vessels in malignant tumors. Also, it detects the cause of hemodialysis fistula dysfunction. We concluded that contrast MRA is a noninvasive imaging modality that can be used for planning the treatment of vascular disorders of the upper extremity.
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PMID:Assessment of vascular disorders of the upper extremity with contrast-enhanced magnetic resonance angiography: pictorial review. 2018 42

Subclavian artery aneurysm is extremely rare, and further aneurysm compressing trachea and leading to breathing difficulty is more exceptional. The most common causes of subclavian artery aneurysm are atherosclerosis, trauma and post-stenotic dilated aneurysm secondary to thoracic outlet syndrome, besides, the rare causes include infective, syphilitic media necrosis and so on. We present a case report in which the patient presented with sever dyspnea due to compression of trachea by a 7 cm large subclavian artery aneurysm. After operation, the patient improved symptomatically. The blood pressure remained stable, blood circulation of right upper extremity was fine, and pulse was improved comparing with that before operation. Chest film confirmed tumor shrank and depressed trachea improved significantly. The patient was discharged 14 days later and continued anticoagulant therapy after discharge. Follow up one month later after the operation revealed breathing difficulty disappeared, and patient was with normal right upper extremity movement and good blood circulation.
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PMID:Operation for huge subclavian artery aneurysm: a case report. 2226 29

Subclavian artery (SA) aneurysms (SCAA) are relatively uncommon but carry a significant risk of rupture, thrombosis and embolism if left untreated. We describe the etiology, mode of presentation and outcome of surgical management of 10 patients presenting with SCAA between January 1990 and December 2010. The mean age was 43.7 years. There were seven men and three women. Five patients had aneurysms due to trauma, four had it due to thoracic outlet syndrome and one had it secondary to atherosclerosis. Five patients presented with ischemic symptoms of the distal upper extremity, while the rest presented with a pulsatile neck mass. All patients were treated surgically. Six patients were approached with combined supra- and infraclavicular incisions. Aneurysm resection with reconstruction using saphenous vein or synthetic grafts was done in eight patients. There was no perioperative mortality. The early patency rate was 100%. Surgical treatment is effective and recommended for most patients with SCAA.
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PMID:Subclavian artery aneurysms: management implications in a resource-limited setting. 2227 3

Aneurysms of the upper extremity mostly originate from trauma, mycotic lesions, thoracic outlet syndrome, previous arteriovenous fistulae, and atherosclerosis. True aneurysms of the brachial and axillary artery are encountered rarely. They can be diagnosed by simple physical examination as a pulsatile mass. However, most of these aneurysms remain asymptomatic until a complication occurs. The primary complication seen with the axillary or brachial artery is embolization. We report 3 large-diameter true brachial artery aneurysms extending to the axillary zone. One of the patients had distal digital emboli causing gangrenous lesions at the finger tips and the other 2 patients had pain and ischemic symptoms in the forearm. All underwent surgical repair. After excision of the aneurysmal segment, arterial continuity was ensured by interposition of a reversed saphenous vein in 2 patients and with a biological vascular graft in 1 patient. Although endovascular techniques are improving, most true brachial artery aneurysms are not anatomically suitable for interventional procedures. Open surgery still preserves its value.
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PMID:Three Cases of Large-Diameter True Brachial and Axillary Artery Aneurysm and a Review of the Literature. 3049 4

Subclavian artery aneurysm is extremely rare, and further aneurysm in a 3-year-old child is more exceptional. Most common causes of subclavian artery aneurysms are atherosclerosis, poststenotic thoracic outlet syndrome, infectious, trauma, and inflammatory arteritis, and connective tissue disorders. Pseudoaneurysms may be due to trauma or any iatrogenic injury to subclavian artery. We present a case report of a 3-year-old male child presented to us with recurrent cough without expectoration for 4-months duration due to compression by a large subclavian artery aneurysm. Patient was successfully managed surgically through left thoracotomy approach. After operation, the patient improved symptomatically. Child was asymptomatic at 3-month follow-up.
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PMID:Interesting case of left subclavian pseudoaneurysm in a child managed successfully. 3306 Oct 9