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Query: UMLS:C0004153 (atherosclerosis)
 77,401 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report an aortographic-pathological correlation in a patient with Takayasu arteritis. The inflammatory activity in Takayasu arteritis gradually subsides and accordingly, the histological appearance goes through a cycle of changes, ranging from acute florid inflammation to an old scarred vessel. At gross pathological inspection, the aortic intima frequently shows longitudinal wrinkling and tree-barking indistinguishable from syphilitic aortitis. In other instances, secondary atherosclerosis totally obscures the underlying changes of aortitis. In such instances, close search at various levels of the aorta is likely to uncover persistent foci of arteritis and thereby permit identification of the pathological changes as secondary to previous aortitis.
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PMID:Takayasu arteritis. An arteriographic-pathological correlation. 0 26

Twenty eight subjects with noisy circulation sindrome (NCS) defined as cases at least, with 4 murmurs in different arteries were studied. They were divided in groups A, B, C formed by 9 normal children, 9 peripheral vascular atherosclerosis adults and 10 Takayasu's arteritis cases, respectively. In the whole population a complete chronometric arterial auscultation and in groups B and C an arteriography of at least 3 arteries with murmurs, were performed. Groups A, B and C had 40, 50 and 37 arterial murmurs, respectively, which were predominantly localized in supraortic trunks, pelvic and phemoral arteries, and supraortic and abdominal regions, respectively. 100, 19.1 and 21.1% of
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PMID:[Noisy circulation syndrome. Study of 28 cases]. 3 22

Forty-nine iliac artery autografts were used in the treatment of renovascular hypertension in 45 patients, including six children. The pathological process was fibromuscular dysplasia in 42, atherosclerosis in two, and Takayasu arteritis in one. The internal iliac artery was used as a graft in 39 patients. The common iliac bifurcation was used in two patients, and the external iliac artery in four patients. Common and external iliac artery continuity was restored with Dacron prostheses. Forty-three patients with 47 autografts have been followed up from one to ten years (average three years). Hypertension was cured or improved in 96% of the patients. Serial follow-up arteriograms as late as ten years after surgery have been obtained in 50% of the patients. No late occlusions occurred. Slight autograft dilation occurred seven years postoperatively in one child. Normal growth of the autograft was exhibited in the remaining five children. No evidence of dilation, aneurysm formation, or stenosis appeared in any other grafts, although one patient developed a new lesion distal to her graft.
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PMID:Aortorenal arterial autografts. 119 Oct 25

Over a 16-year period, 205 patients with hypertension were shown to have a renovascular aetiology. Of these, 125 (61 per cent) had Takayasu's arteritis, 58 (28.3 per cent) had fibromuscular dysplasia, 16 (7.8 per cent) had atherosclerosis, five (2.4 per cent) had polyarteritis nodosa and one (0.5 per cent) had renal artery aneurysm. Among patients with Takayasu's arteritis, males were affected as commonly as females. The mean age of these patients at the time of detection was 26.8 +/- 8.6 years (range 5-52 years). Type I arteritis was seen in nine (7.2 per cent), Type II in 40 (32 per cent) and Type III in 76 (60.8 per cent) patients. The abdominal aorta was involved in 117 (93.3 per cent) patients. Takayasu's arteritis was associated with ulcerative colitis in two patients and with renal amyloidosis and focal segmental glomerulosclerosis with a nephrotic syndrome in one patient each. Surgical intervention consisting of bypass procedures, autotransplantation or nephrectomy was performed in 17 (13.6 per cent) and angioplasty in nine (7.2 per cent) patients. Cure and improvement in blood pressure was observed in 82.4 per cent and 77.8 per cent respectively. Adequate control of blood pressure was achieved with drugs only in 22 (22.2 per cent) patients. A definite cause and effect relationship could not be established between any infective or immunological disorder and Takayasu's arteritis. Takayasu's arteritis is a far more common cause of renovascular hypertension in Indian population than fibromuscular dysplasia or atherosclerosis, which are more common in the western population.
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PMID:Renovascular hypertension due to Takayasu's arteritis among Indian patients. 136 62

The aortic arch syndrome characterised by diminished or absent pulses in the arteries arising from the aortic arch has many etiologies, such as syphilitic aortitis, dissection of the aorta, atherosclerosis and Takayasu's arteritis. The diagnostic criteria of Takayasu's arteritis often do not mention histological investigations. We observed a case of an aortic arch syndrome, presenting as a classical case of Takayasu's arteritis but caused by a severe form of atherosclerosis.
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PMID:Takayasu's disease and atherosclerosis. 167 30

An autopsy case of an elderly man with Takayasu's arteritis and atherosclerosis is presented. Ischemic signs and symptoms including anginal attack were aggravated with activity of arteritis despite administration of prednisolone throughout the entire course. The autopsy revealed severe atherosclerosis over the aorta and its branches, and arteritis in the fibrotic stage in localized area. Vessels of vital organs including heart and kidneys, did not show Takayasu's arteritis but were atherosclerotic. This case highlights the numerous problems encountered in the treatment of elderly patients with vasculitis such as Takayasu's arteritis.
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PMID:Takayasu's arteritis with heart failure due to atherosclerosis. 198 Mar 20

A total of 18 patients underwent surgical correction of renal hypertension secondary to Takayasu's disease after unsuccessful maximum medical therapy. Although the patients required an extensive surgical procedure, the morbidity and mortality rates were low (1 perioperative death in 18 patients). Followup showed that 67 per cent of the patients were cured of the hypertension and 28 per cent were improved. The results appear as good as those seen in the treatment of renovascular hypertension owing to fibromuscular disease or atherosclerosis.
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PMID:Renovascular hypertension and Takayasu's disease. 286 77

Non specific inflammatory involvement of the subclavian arteries due to Takayasu's disease is rare, compared to the frequency of atherosclerosis. A personal series of 23 cases of brachiocephalic arteritis, observed between 1967 and 1980 is presented. Mean age of the patients is 30 years, 60% are females. Supra-aortic trunks are only involved in 15 patients and associated with abdominal aorta and renal arteries in 8. By passes with prosthetic grafts or saphenous veins have been most frequently used in revascularization techniques performed in 23 patients, 2 patients have shown progressive evolution with multiple involvement between 4 and 6 years. One death occurred during recurrent active process with occlusion of all brachiocephalic arteries. With a mean follow up of 8 years, 80% of the surgical patients are stabilized with a satisfactory clinical and anatomical result. Operative indication must take into account the sites of occlusive lesions, symptoms and anatomical stage of arteritis.
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PMID:Upper limb arteritis in Takayasu's disease. Surgical treatment and results. 287 Jan 25

Eight cases of renovascular hypertension (RVH) encountered in the University College Hospital (UCH), Ibadan, Nigeria between 1977 and 1982 are presented and reviewed along with four additional cases, previously reported from this hospital. Seven of these cases were due to fibromuscular disease (FMD); four were due to involvement of the renal arteries by aortic aneurysms and one was due to Takayasu's arteriopathy. No case due to atherosclerosis was seen, which is in sharp contrast to the situation in the western world where atherosclerosis is the commonest cause of renal artery stenosis (RAS). Detection and management of RVH are highlighted and the current concepts and features of FMD are briefly discussed.
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PMID:Radiological assessment of renovascular hypertension in Ibadan, Nigeria. 303 62

From January 1978 through December 1987, 22 patients underwent 23 renal autotransplantation procedures for the treatment of renovascular hypertension through the retroperitoneal approach. The causes of the renal artery stenosis were as follows: atherosclerosis (15), fibromuscular dysplasia (6), and Takayasu's arteritis (1). Indications for renal autotransplantation were as follow: disease extending into the renal artery branches (10), stenosis of multiple renal arteries (6), atherosclerotic aorta in high-risk patients (4), and stenosis of renal artery in children (2). The mean preoperative blood pressure of 205 +/- 6/109 +/- 3 mm Hg decreased significantly to 139 +/- 4/77 +/- 2 mm Hg (p less than 0.001). The serum creatinine decreased significantly from a mean preoperative level of 2.2 +/- 0.8 mg/dl to a mean postoperative level of 1.4 +/- 0.4 mg/dl (p less than 0.05). Eleven patients with preoperative renal dysfunction had a significant decrease in the serum creatinine from a mean preoperative level of 3.4 +/- 0.3 mg/dl to a mean postoperative level of 1.9 +/- 0.2 mg/dl (p less than 0.001). One operative death occurred as a result of myocardial infarction. There were three postoperative complications, none of which affected the ultimate result in blood pressure or renal function. This experience demonstrates that in selected patients, renal autotransplantation is an excellent alternative in the surgical treatment of renovascular hypertension.
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PMID:Renal autotransplantation: an alternative to standard renal revascularization procedures. 305 72


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