Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0004135 (ATM)
13,001 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein ATM 5714 AT1 4545 angiotensin II 2486 p53 2085 Ang II 1578 ATR 1456 AT2 1404 A-T 1328 renin 1157 Mol 1106 Sep 864 H2AX 706 Chk1 687 BRCA1 678 DNA-dependent protein kinase 593 Chk2 551 histone 377 BRCA2 377 p21 376 ANG 349 ataxia telangiectasia mutated 312 ATM protein 302 ACE 301 angiotensin II receptor 298 53BP1 292 NBS1 267 angiotensin receptor 242 PARP 235 bradykinin 210 AT1R 210 CHK2 198 Rad50 196 angiotensinogen 190 caspase-3 189 telomeric 185 insulin 174 collagen 173 MRE11 170 CHEK2 169 CHK1 168 RAD51 164 MAPK 163 lymphoid 161 p38 159 PTEN 153 PALB2 145 mTOR 143 ERK1 141 phosphatase 137 ATP 130 RAD50 128 PI3K 128 ROS 116 cytokine 116 threonine 114 MDC1 112 like kinase 112 AKT 111 ubiquitin 111 ERK 110 Renin 110 Rad51 108 vasopressin 108 tyrosine kinase 108 cancer susceptibility 100 MDM2 97 cyclin 94 ATPase 92 JNK 91 phosphatidylinositol 3-kinase 91 nitric oxide synthase 90 CDKN2A 88 Bcl-2 87 endonuclease 87 AT1B 86 phosphorylating 84 proteasome 83 tumour suppressor 83 RPA 83 endothelin-1 82 more...

Disease ATM 13001 cancer 2888 tumor 1374 hypertension 973 breast cancer 581 immunodeficiency 412 tumorigenesis 289 leukemia 264 heart failure 235 carcinogenesis 225 diabetes 212 NBS 191 BLM 175 chronic lymphocytic leukemia 174 lymphoma 169 ovarian cancer 167 genetic disorder 163 carcinoma 158 xeroderma pigmentosum 152 telangiectasia 148 prostate cancer 138 anemia 138 myocardial infarction 136 chronic lymphocytic leukemia 132 atherosclerosis 129 stroke 129 Fanconi 127 adenocarcinoma 117 ischemia 113 tumor growth 109 lung cancer 108 melanoma 103 Epstein 102 renal disease 98 proteinuria 95 tumor progression 90 ventricular hypertrophy 88 cardiovascular disease 88 colorectal cancer 87 WRN 86 preeclampsia 84 APC 83 essential hypertension 83 obesity 83 NAME 81 hepatocellular carcinoma 79 Fanconi syndrome 77 Alzheimer's disease 76 congestive heart failure 75 diabetic nephropathy 72 MCF 72 apraxia 72 neuroblastoma 72 glioma 72 squamous cell carcinoma 70 pancreatic cancer 69 Hodgkin's disease 66 mantle cell lymphoma 66 glioblastoma 65 premature aging 65 Cockayne syndrome 59 immune deficiency 58 pertussis 57 retinoblastoma 57 colon cancer 56 gastric cancer 56 SCID 55 acute myeloid leukemia 54 type 2 diabetes 53 metastases 52 Leukemia 50 Friedreich's ataxia 50 renal failure 48 non-small cell lung cancer 48 IgA deficiency 47 glomerulosclerosis 45 myocardial ischemia 45 ARF 45 skin cancer 44 multiple myeloma 42 more...

Symptom ataxia 233 cerebellar ataxia 154 cough 41 collapse 40 dystonia 28 seizures 24 anesthesia 24 starvation 22 pain 17 tremor 16 functional recovery 14 myoclonus 13 exhaustion 12 fatigue 11 headache 11 weakness 10 diarrhea 9 dysarthria 9 chorea 8 acute stress 8 angina 7 hepatosplenomegaly 7 respiratory distress 7 nausea 6 incoordination 6 dizziness 6 erythema 5 thinning 5 hyperoxia 5 ataxic gait 5 vomiting 5 splenomegaly 4 overweight 4 anorexia 3 polyuria 3 hypotonia 3 acidity 3 hepatomegaly 3 oliguria 3 polydipsia 3 abnormal gait 3 spasticity 3 CSR 2 Rest tremor 2 syncope 2 shortness of breath 2 sleepiness 2 pallor 2 dyspnea 2 hypothermia 2 discomfort 2 impaired motor coordination 2 spasm 2 cachexia 2 memory loss 2 discomfort 2 clumsiness 2 hypertonia 2 neurological disability 2 Cri du chat 1 Decreased activity 1 constipation 1 chronic cough 1 Cushingoid 1 drooling 1 Anoxia 1 tinnitus 1 Stiffness 1 torticollis 1 regurgitation 1 arthralgia 1 Ill 1 bradykinesia 1 asthenia 1 staggering gait 1 blackout 1 athetosis 1 back pain 1 abdominal pain 1 Macula 1 more...

Drug Angiotensin II 698 caffeine 210 Cardiovasc 174 ROS 116 lysine 89 BLM 61 MAP 49 Dermatol 48 ETA 43 Valsartan 37 Captopril 34 Mutagen 32 IL-2 17 ascorbate 17 Nephron 16 Aliskiren 15 NADH 14 IFN-gamma 14 Indomethacin 13 vitamin E 12 G418 12 Asn 10 Nephron 10 Olmesartan 10 CSF 10 nitroglycerin 10 MOF 10 Gel 10 Etoposide 10 ICI 10 CTX 10 DNase I 8 MRC 8 Neocarzinostatin 7 CPT-11 7 Dial 7 Ethanol 7 ETS 7 NVP 6 EE2 6 Heme 6 IL-1ra 5 TEL 5 Alanine 5 Adriamycin 5 Oxaliplatin 5 Imatinib 5 Nitric Oxide 5 Glutathione 5 Losartan potassium 5 Atenolol 5 Irinotecan 5 BH4 4 Bosentan 4 Monit 4 ABC 4 MDS 4 Photofrin 4 CAZ 4 CTX 4 Bosentan 4 Olmesartan medoxomil 4 ADR 4 niacin 4 CTX 4 Parkin 3 TTC 3 Atropine 3 Micardis 3 Fructose 3 Amiloride 3 PTC 3 DEX 3 Lovastatin 3 EPA 3 Spectrum 3 Leaf 3 Cilazapril 3 Irofulven 3 Spectrum 3 more...

Enzyme renin 1157 ACE 514 protein kinase 512 mitogen-activated protein kinase 454 ERK 345 PARP 277 protein kinase C 212 focal adhesion kinase 138 topoisomerase 138 caspase-3 133 topoisomerase 129 NADPH oxidase 117 phospholipase C 111 ATPase 99 cdc2 96 NADPH oxidase 93 phosphatidylinositol 3-kinase 91 endonuclease 87 APC 83 proteasome 83 superoxide dismutase 75 MEK 73 RNA polymerase 68 AMP-activated protein kinase 68 calcineurin 64 catalase 64 luciferase 60 STK11 54 AMPK 54 AMPK 53 NO synthase 52 MAP 47 DNA polymerase 46 phosphoinositide 3-kinase 41 reverse transcriptase 38 caspase-9 34 CD10 33 collagenase 26 kallikrein 25 glutathione S-transferase 24 ribonucleotide reductase 24 histone acetyltransferase 24 tyrosine hydroxylase 23 polo-like kinase 1 22 ribonucleotide reductase 22 angiotensin-converting enzyme 2 21 IKK 21 phosphodiesterase 20 phospholipase A2 20 chymase 20 caspase-8 20 protein phosphatase 2A 20 guanylate cyclase 19 adenylate cyclase 19 RNase 19 transcriptase 19 RNase 19 peroxidase 16 DNA methyltransferase 16 beta-galactosidase 15 glutathione peroxidase 15 DNA ligase 14 DNA ligase 14 NOS 13 thrombin 13 lactate dehydrogenase 13 AGT 11 alkaline phosphatase 11 alanine aminotransferase 11 thymidine kinase 11 GSK 10 glucose-6-phosphate dehydrogenase 10 xanthine oxidase 10 CPT 10 CPT 10 phospholipase D 10 CPT 10 isocitrate dehydrogenase 9 isocitrate dehydrogenase 9 caspase-2 9 more...

Compound DNA 5698 Ang II 1006 Angiotensin II 919 Dec 914 oxygen 528 Clin 515 sodium 417 calcium 412 Losartan 386 acetate 377 serine 361 aldosterone 332 water 298 nitric oxide 246 caffeine 210 threonine 199 tyrosine 194 arginine 185 salt 184 glucose 167 PD 123319 154 ATP 131 phosphate 124 lysine 119 Cardiol 115 hydrogen 99 cAMP 97 potassium 97 alanine 96 BLM 73 cysteine 68 Candesartan 68 TNF 68 urea 64 cGMP 63 ADP 62 noradrenaline 60 PD 123177 60 ADP 59 ADP 59 leucine 56 pyridine 53 glutamate 51 creatinine 51 N-acetylcysteine 49 COS 49 MAP 47 methionine 47 GTP 47 MDA 46 GSH 45 GSH 45 ADP-ribose 44 H2O2 44 ETA 43 nitrogen 42 methyl methanesulfonate 42 Phe 41 MTT 41 MEK 39 Asp 38 pyrimidine 37 pyrimidine 37 iron 36 ethanol 36 prostacyclin 36 NADPH 35 Serine 35 AMP 35 NADPH 34 His 34 Wortmannin 33 ACTH 33 Telmisartan 32 Ile 31 Irbesartan 31 glutamine 31 XPA 30 XPA 30 EXP 3174 30 more...

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