Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004135 (ATM)
13,001 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ATM 5714
AT1 4545
angiotensin II 2486
p53 2085
Ang II 1578
ATR 1456
AT2 1404
A-T 1328
renin 1157
Mol 1106
Sep 864
H2AX 706
Chk1 687
BRCA1 678
DNA-dependent protein kinase 593
Chk2 551
BRCA2 377
histone 377
p21 376
ANG 349
ataxia telangiectasia mutated 312
ATM protein 302
ACE 301
angiotensin II receptor 298
53BP1 292
NBS1 267
angiotensin receptor 242
PARP 235
bradykinin 210
AT1R 210
CHK2 198
Rad50 196
angiotensinogen 190
caspase-3 189
telomeric 185
insulin 174
collagen 173
MRE11 170
CHEK2 169
CHK1 168
more...
Disease
ATM 13001
cancer 2888
tumor 1374
hypertension 973
breast cancer 581
immunodeficiency 412
tumorigenesis 289
leukemia 264
heart failure 235
carcinogenesis 225
diabetes 212
NBS 191
BLM 175
chronic lymphocytic leukemia 174
lymphoma 169
ovarian cancer 167
genetic disorder 163
carcinoma 158
xeroderma pigmentosum 152
telangiectasia 148
anemia 138
prostate cancer 138
myocardial infarction 136
chronic lymphocytic leukemia 132
atherosclerosis 129
stroke 129
Fanconi 127
adenocarcinoma 117
ischemia 113
tumor growth 109
lung cancer 108
melanoma 103
Epstein 102
renal disease 98
proteinuria 95
tumor progression 90
ventricular hypertrophy 88
cardiovascular disease 88
colorectal cancer 87
WRN 86
more...
Symptom
ataxia 233
cerebellar ataxia 154
cough 41
collapse 40
dystonia 28
anesthesia 24
seizures 24
starvation 22
pain 17
tremor 16
functional recovery 14
myoclonus 13
exhaustion 12
headache 11
fatigue 11
weakness 10
diarrhea 9
dysarthria 9
chorea 8
acute stress 8
respiratory distress 7
hepatosplenomegaly 7
angina 7
nausea 6
incoordination 6
dizziness 6
vomiting 5
thinning 5
ataxic gait 5
erythema 5
hyperoxia 5
overweight 4
splenomegaly 4
abnormal gait 3
anorexia 3
hepatomegaly 3
polydipsia 3
polyuria 3
hypotonia 3
acidity 3
more...
Drug
Angiotensin II 698
caffeine 210
Cardiovasc 174
ROS 116
lysine 89
BLM 61
MAP 49
Dermatol 48
ETA 43
Valsartan 37
Captopril 34
Mutagen 32
IL-2 17
ascorbate 17
Nephron 16
Aliskiren 15
IFN-gamma 14
NADH 14
Indomethacin 13
G418 12
vitamin E 12
Nephron 10
MOF 10
Gel 10
nitroglycerin 10
CTX 10
Olmesartan 10
CSF 10
Etoposide 10
Asn 10
ICI 10
DNase I 8
MRC 8
Neocarzinostatin 7
CPT-11 7
ETS 7
Ethanol 7
Dial 7
EE2 6
Heme 6
more...
Enzyme
renin 1157
ACE 514
protein kinase 512
mitogen-activated protein kinase 454
ERK 345
PARP 277
protein kinase C 212
topoisomerase 138
focal adhesion kinase 138
caspase-3 133
topoisomerase 129
NADPH oxidase 117
phospholipase C 111
ATPase 99
cdc2 96
NADPH oxidase 93
phosphatidylinositol 3-kinase 91
endonuclease 87
proteasome 83
APC 83
superoxide dismutase 75
MEK 73
AMP-activated protein kinase 68
RNA polymerase 68
catalase 64
calcineurin 64
luciferase 60
AMPK 54
STK11 54
AMPK 53
NO synthase 52
MAP 47
DNA polymerase 46
phosphoinositide 3-kinase 41
reverse transcriptase 38
caspase-9 34
CD10 33
collagenase 26
kallikrein 25
ribonucleotide reductase 24
more...
Compound
DNA 5698
Ang II 1006
Angiotensin II 919
Dec 914
oxygen 528
Clin 515
sodium 417
calcium 412
Losartan 386
acetate 377
serine 361
aldosterone 332
water 298
nitric oxide 246
caffeine 210
threonine 199
tyrosine 194
arginine 185
salt 184
glucose 167
PD 123319 154
ATP 131
phosphate 124
lysine 119
Cardiol 115
hydrogen 99
potassium 97
cAMP 97
alanine 96
BLM 73
cysteine 68
Candesartan 68
TNF 68
urea 64
cGMP 63
ADP 62
PD 123177 60
noradrenaline 60
ADP 59
ADP 59
more...