Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0004135 (
ATM
)
13,001
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ATM
5714
AT1
4545
angiotensin II
2486
p53
2085
Ang II
1578
ATR
1456
AT2
1404
A-T
1328
renin
1157
Mol
1106
Sep
864
H2AX
706
Chk1
687
BRCA1
678
DNA-dependent protein kinase
593
Chk2
551
BRCA2
377
histone
377
p21
376
ANG
349
ataxia telangiectasia mutated
312
ATM protein
302
ACE
301
angiotensin II receptor
298
53BP1
292
NBS1
267
angiotensin receptor
242
PARP
235
bradykinin
210
AT1R
210
CHK2
198
Rad50
196
angiotensinogen
190
caspase-3
189
telomeric
185
insulin
174
collagen
173
MRE11
170
CHEK2
169
CHK1
168
more...
Disease
ATM
13001
cancer
2888
tumor
1374
hypertension
973
breast cancer
581
immunodeficiency
412
tumorigenesis
289
leukemia
264
heart failure
235
carcinogenesis
225
diabetes
212
NBS
191
BLM
175
chronic lymphocytic leukemia
174
lymphoma
169
ovarian cancer
167
genetic disorder
163
carcinoma
158
xeroderma pigmentosum
152
telangiectasia
148
anemia
138
prostate cancer
138
myocardial infarction
136
chronic lymphocytic leukemia
132
atherosclerosis
129
stroke
129
Fanconi
127
adenocarcinoma
117
ischemia
113
tumor growth
109
lung cancer
108
melanoma
103
Epstein
102
renal disease
98
proteinuria
95
tumor progression
90
ventricular hypertrophy
88
cardiovascular disease
88
colorectal cancer
87
WRN
86
more...
Symptom
ataxia
233
cerebellar ataxia
154
cough
41
collapse
40
dystonia
28
anesthesia
24
seizures
24
starvation
22
pain
17
tremor
16
functional recovery
14
myoclonus
13
exhaustion
12
headache
11
fatigue
11
weakness
10
diarrhea
9
dysarthria
9
chorea
8
acute stress
8
respiratory distress
7
hepatosplenomegaly
7
angina
7
nausea
6
incoordination
6
dizziness
6
vomiting
5
thinning
5
ataxic gait
5
erythema
5
hyperoxia
5
overweight
4
splenomegaly
4
abnormal gait
3
anorexia
3
hepatomegaly
3
polydipsia
3
polyuria
3
hypotonia
3
acidity
3
more...
Drug
Angiotensin II
698
caffeine
210
Cardiovasc
174
ROS
116
lysine
89
BLM
61
MAP
49
Dermatol
48
ETA
43
Valsartan
37
Captopril
34
Mutagen
32
IL-2
17
ascorbate
17
Nephron
16
Aliskiren
15
IFN-gamma
14
NADH
14
Indomethacin
13
G418
12
vitamin E
12
Nephron
10
MOF
10
Gel
10
nitroglycerin
10
CTX
10
Olmesartan
10
CSF
10
Etoposide
10
Asn
10
ICI
10
DNase I
8
MRC
8
Neocarzinostatin
7
CPT-11
7
ETS
7
Ethanol
7
Dial
7
EE2
6
Heme
6
more...
Enzyme
renin
1157
ACE
514
protein kinase
512
mitogen-activated protein kinase
454
ERK
345
PARP
277
protein kinase C
212
topoisomerase
138
focal adhesion kinase
138
caspase-3
133
topoisomerase
129
NADPH oxidase
117
phospholipase C
111
ATPase
99
cdc2
96
NADPH oxidase
93
phosphatidylinositol 3-kinase
91
endonuclease
87
proteasome
83
APC
83
superoxide dismutase
75
MEK
73
AMP-activated protein kinase
68
RNA polymerase
68
catalase
64
calcineurin
64
luciferase
60
AMPK
54
STK11
54
AMPK
53
NO synthase
52
MAP
47
DNA polymerase
46
phosphoinositide 3-kinase
41
reverse transcriptase
38
caspase-9
34
CD10
33
collagenase
26
kallikrein
25
ribonucleotide reductase
24
more...
Compound
DNA
5698
Ang II
1006
Angiotensin II
919
Dec
914
oxygen
528
Clin
515
sodium
417
calcium
412
Losartan
386
acetate
377
serine
361
aldosterone
332
water
298
nitric oxide
246
caffeine
210
threonine
199
tyrosine
194
arginine
185
salt
184
glucose
167
PD 123319
154
ATP
131
phosphate
124
lysine
119
Cardiol
115
hydrogen
99
potassium
97
cAMP
97
alanine
96
BLM
73
cysteine
68
Candesartan
68
TNF
68
urea
64
cGMP
63
ADP
62
PD 123177
60
noradrenaline
60
ADP
59
ADP
59
more...