Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0004135 (
ATM
)
13,001
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Potassium sparing diuretics in combination with thiazides represent a therapeutical enrichment if applied correctly that is with respect to contraindications, interactions (especially with ACE-inhibitors and
AT1
-antagonists) and to pharmacokinetic properties.
Triamterene
has to be administered twice a day while amiloride and spironolactone are effective for 24 hours. Of course, pharmacokinetic parameters of potassium sparing diuretics have to be considered also in fixed combinations.
...
PMID:[Pharmacology of potassium-sparing diuretics]. 919 48
