Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0004135 (
ATM
)
13,001
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We retrospectively reviewed the databases of seven studies on acute lymphoblastic leukemia (ALL) by the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) to identify patients with associated genetic disease, other than Down's syndrome. Forty-two patients were reported to have associated genetic conditions that included beta-thalassemia (n=10),
ataxia-telangiectasia
(n=5), neurofibromatosis (n=3),
Sotos syndrome
(n=2) and other individual conditions. Patients with
ataxia-telangiectasia
, all with T-cell ALL, had a higher frequency of adverse events.
...
PMID:Acute lymphoblastic leukemia in children with associated genetic conditions other than Down's syndrome. The AIEOP experience. 1643 85
