Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0004134 (ataxia)
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Human Gene/Protein
methyl-CpG binding domain protein 5 11.0
SYNE1 protein 11.0
CAG repeat domain 11.0
phosphatidylinositol glycan class S 11.0
MPDZ protein 11.0
chromosome 6 open reading frame 70 11.0
Sorting nexin-14 11.0
B3GalNAc-T2 11.0
PAFAH1B3 protein 11.0
SRGAP3 protein 11.0
G protein-coupled receptor 26 11.0
ceroid-lipofuscinosis, neuronal 5 11.0
C10orf6 11.0
STM-7 11.0
KIAA0960 11.0
CABC1 protein 11.0
sterile alpha motif domain containing 9-like 11.0
MFSD7 11.0
ITPR1 protein 10.4
IOSCA 10.3
CACH 10.3
SPTBN2 10.3
alpha1A-voltage-dependent calcium channel 10.2
senataxin 10.2
SCA11 10.2
SCA5 10.2
anoctamin 10 10.2
aprataxin 10.1
SCA2 10.1
APTX 10.0
SCA3 10.0
ALS4 10.0
SCA8 10.0
DNAJC8 10.0
Tau-tubulin kinase 1 10.0
low molecular mass ubiquinone-binding protein 10.0
zinc finger protein 4 10.0
OSBPL11 10.0
KIAA0226 10.0
ATP synthase subunit a 10.0
CLK2 protein 10.0
GRID2 protein 10.0
UROC1 10.0
feline leukemia virus subgroup C cellular receptor 1 10.0
GDAP2 10.0
THG1L 10.0
SCA1 9.9
puratrophin-1 9.9
SCA12 9.9
SCA7 9.9
SCA17 9.8
CACNA1A 9.8
ASFMR1 9.7
Caytaxin 9.7
TGM6 9.7
SACS 9.7
ANO10 9.7
RTN4IP1 9.6
ATLD 9.6
KCNC3 9.6
SANDO 9.6
calcium channel alpha 1A subunit 9.6
FAM36A 9.6
SCA10 9.6
ataxin-1 9.6
NARP 9.6
SETX 9.6
RNF170 9.6
ATXN3 9.5
AFG3L2 9.5
EA2 9.5
ataxin-3 9.5
MTATP6 9.5
SLC9A6 9.4
TTBK2 9.4
ATXN1 protein 9.4
ADP-ribosylation factor guanine nucleotide-exchange factor 2 9.4
MSTO1 9.4
ZFP106 9.4
STM7 9.4
more...
Disease
Late onset cerebellar ataxia 11.0
Vestibular ataxia 11.0
Sanger-Brown 11.0
Deficiency of pyruvate decarboxylase 11.0
ataxia-deafness-retardation syndrome 11.0
Richards-Rundle syndrome (RRS) 11.0
Chronic idiopathic ataxic neuropathy 11.0
Deficiency of glutamate dehydrogenase 11.0
Gaze palsy 11.0
Central vestibular nystagmus 11.0
AXPC1 11.0
Immune-mediated conjunctivitis 11.0
Other CNS disorders 11.0
Hereditary optic atrophy 11.0
Late cortical cerebellar atrophy 11.0
Intermittent maple syrup urine disease 11.0
Cerebral ataxia 11.0
Spinal ataxia 11.0
NPHP1, DEL 11.0
FRDA2 11.0
SCA23 10.8
SCA27 10.7
SCA5 10.6
Episodic ataxia 10.6
SCAE 10.6
SCA13 10.5
IOSCA 10.5
SCA19 10.5
SCA14 10.4
SCA11 10.4
SCAR6 10.4
SCAN1 10.4
Equine ehrlichiosis 10.4
SCA28 10.3
FXTAS 10.3
SCA16 10.3
SCA4 10.3
SCA15 10.2
Spastic ataxia 10.2
Early onset cerebellar ataxia with retained tendon reflexes 10.2
SCA6 10.2
Behr syndrome 10.1
MILS 10.1
SCA8 10.0
SCA2 10.0
Opsoclonus myoclonus 10.0
ATLD 10.0
Fitzsimmons syndrome 10.0
Equine degenerative myeloencephalopathy 10.0
Tropical ataxic neuropathy 10.0
Brain syndrome 10.0
childhood cerebellar astrocytoma 10.0
Fibrinous peritonitis 10.0
hereditary cerebellar degeneration 10.0
Early Onset Cerebellar Ataxia 10.0
Increased intracranial pressure and hydrocephalus 10.0
CDG Ic 10.0
Cryptococcal choroiditis 10.0
Familial acantholysis 10.0
SCA26 10.0
Cryptococcal choroiditis 10.0
familial striatal degeneration 10.0
CDG Ie 10.0
Congenital cerebellar ataxia 10.0
Hallgren's syndrome 10.0
Pallidoluysian atrophy 10.0
cerebellotrigeminal and focal dermal dysplasia 10.0
Supranuclear gaze palsy 10.0
AOA2 10.0
Specific viral infections 10.0
SCA12 9.9
SCA7 9.9
SCA1 9.9
Machado-Joseph disease 9.8
SCA17 9.8
hereditary ataxia 9.8
Opsoclonus 9.7
SACS 9.7
Miller Fisher syndrome 9.7
SANDO 9.6
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Symptom
Gait deviation 11.0
ataxia 11.0
Palatal paralysis 11.0
Sensory ataxia 10.5
Limb ataxia 10.1
poor balance and coordination 10.0
Ataxic 9.6
Truncal ataxia 9.6
intention tremor 9.4
Extrapyramidal rigidity 9.4
cerebellar ataxia 9.3
Ophthalmoparesis 9.2
Bruns nystagmus 9.0
ataxic gait 8.9
dysarthria 8.9
Limb weakness 8.8
abiotrophy 8.7
Dysdiadochokinesis 8.6
sense loss 8.6
Acute vertigo 8.6
Tandem gait 8.6
staggering gait 8.4
Premature loss of teeth 8.4
ophthalmoplegia 8.4
athetosis 8.3
Vertigo/dizziness 8.2
myoclonus 8.1
muscular incoordination 8.0
Transient neurological symptoms 8.0
Pyramidal signs 8.0
incoordination 8.0
clumsiness 7.9
Phonophobia 7.8
hyperesthesia 7.6
Apraxic 7.5
prostration 7.4
abnormal gait 7.4
Grip strength decreased 7.4
Postural tremor 7.4
hemiparesthesia 7.4
Bell's phenomenon 7.3
Retropulsion 7.3
Opisthotonus 7.3
hypalgesia 7.2
tremor 7.2
Motor dysfunction 7.2
hypotonia 7.2
External ophthalmoplegia 7.2
spasticity 7.1
amimia 7.1
loss of balance 7.1
astasia 7.0
chorea 7.0
unable to urinate 7.0
Nuchal rigidity 7.0
paresis 6.9
Lhermitte's sign 6.9
giddiness 6.9
giddiness 6.9
eye discharge 6.9
vertigo 6.9
paraparesis 6.9
abnormal breathing 6.8
Action myoclonus 6.8
dystonia 6.7
Burning pain 6.7
asterixis 6.7
GI pain 6.7
hyperemesis gravidarum 6.6
Spastic 6.5
carpopedal spasm 6.4
labored breathing 6.4
Drop attacks 6.4
intestinal pain 6.4
hemihypesthesia 6.4
lethargy 6.4
dysesthesia 6.3
Cramping 6.3
facial droop 6.3
torticollis 6.3
more...
Drug
Midaflur 11.0
Fluzinamide 11.0
Liskantin 10.0
Butaclamol hydrochloride 10.0
Hirtonin 10.0
Lactomin 10.0
Metacresol 10.0
Marezine 9.4
Tandospirone citrate 9.4
Sulfobromophthalein sodium 9.4
Ralitoline 9.0
Loxapin 8.4
Loxapine succinate 8.2
Cerebyx 8.2
Bentos 8.2
Ganaxolone 7.6
Abecarnil 7.4
Edrophonium chloride 7.4
Cupric chloride 7.4
Flurbiprofen axetil 7.3
Selenium sulfide 7.2
Arundic acid 7.1
Brotizolam 6.9
Physostigmine salicylate 6.9
Nabilone 6.9
Bextra 6.8
Sulthiame 6.7
4-Methylimidazole 6.7
Parnate 6.7
Idebenone 6.6
SUN 1165 6.6
Foscavir 6.5
Fosphenytoin 6.5
Chantix 6.4
Zosyn 6.4
Miglustat 6.3
Muzolimine 6.2
Hypnomidate 6.2
Zuclopenthixol 6.1
Topamax 6.1
DFP 6.0
Lofexidine 6.0
Irofulven 6.0
Versed 6.0
Swainsonine 5.9
Anexate 5.9
Gadobenate dimeglumine 5.8
Gamma-Aminobutyric acid 5.8
Narasin 5.7
Doxifluridine 5.7
GVG 5.6
Moxidectin 5.6
Lasalocid 5.6
Eucalyptus oil 5.6
Gabapentin 5.5
Zofran 5.5
Progabide 5.5
Ziconotide 5.5
PCP 5.5
Lioresal 5.4
Pregabalin 5.4
Perphenazine 5.3
Zmax 5.3
Sodium valproate 5.2
Benserazide 5.2
Carbidopa 5.2
Stiripentol 5.2
Rufinamide 5.1
Beraprost sodium 4.9
Gamma globulin 4.9
AGG 4.8
DM1 4.7
Corn oil 4.7
Diamox 4.7
Atipamezole 4.6
Vitamin E 4.5
Piracetam 4.5
7-Nitroindazole 4.5
Lovenox 4.5
Valdecoxib 4.5
more...
Enzyme
leucine decarboxylase 9.6
m-AAA protease 8.7
phytanoyl-CoA hydroxylase 8.5
aspartate N-acetyltransferase 7.4
biotinidase 6.8
methionyl-tRNA formyltransferase 6.5
5,10-methenyltetrahydrofolate synthetase 6.4
tripeptidyl peptidase 6.4
phosphomannomutase 6.2
pantothenate kinase 6.0
phosphoethanolamine cytidylyltransferase 6.0
neuropathy target esterase 5.8
succinic semialdehyde dehydrogenase 5.7
CYP7B1 5.6
2',3'-cyclic nucleotide phosphohydrolase 5.6
3'-phosphatase 5.6
PCP 5.4
CYP27A1 5.4
alanyl-tRNA synthetase 5.2
GMP reductase 5.2
aspartyl-tRNA synthetase 5.1
alpha-N-acetylglucosaminidase 5.1
UDP-galactose:ceramide galactosyltransferase 5.1
PRPP synthetase 5.1
N-acetylglucosaminyltransferase II 5.0
ethanolamine kinase 5.0
urocanase 5.0
VOR 5.0
Lod 4.9
palmitoyl-protein thioesterase 4.9
thiaminase 4.9
10-formyltetrahydrofolate dehydrogenase 4.9
dihydrolipoamide succinyltransferase 4.8
polynucleotide kinase 4.7
mevalonate kinase 4.7
thiaminase 4.6
splicing endonuclease 4.6
CYP46A1 4.5
asparaginyl-tRNA synthetase 4.5
sepiapterin reductase 4.5
isovaleryl-CoA dehydrogenase 4.4
aspartoacylase 4.4
hexosaminidase 4.4
thiamine pyrophosphokinase 4.4
transketolase 4.3
aconitase 4.3
galactose-1-phosphate uridylyltransferase 4.2
GalNAc-T 4.2
4-hydroxyphenylpyruvate dioxygenase 4.1
alpha-methylacyl-CoA racemase 4.1
glucosylceramide synthase 4.1
PHT 4.0
sulfiredoxin 4.0
nicotinamide mononucleotide adenylyltransferase 4.0
GABA transaminase 3.9
galactocerebrosidase 3.9
isopeptidase 3.8
GalT 3.8
pyruvate dehydrogenase 3.8
SCP 3.7
pyruvate dehydrogenase 3.7
pyruvate dehydrogenase 3.7
ubiquitin-protein ligase 3.6
alpha-ketoglutarate dehydrogenase 3.6
TPP 3.6
methionine synthase 3.6
PDH 3.6
thyroid peroxidase 3.5
GCA 3.5
methionine synthase 3.5
DNA ligase 3.5
DNA ligase 3.5
PME 3.4
adenylosuccinate lyase 3.4
histidyl-tRNA synthetase 3.4
mannosidase II 3.4
methionine synthase reductase 3.3
complex I 3.3
argininosuccinate lyase 3.3
arylsulfatase A 3.3
more...
Compound
Cyclizine hydrochloride 11.0
Methylene bis(thiocyanate) 11.0
phosphorofluoridic acid 10.0
Elamol 10.0
Phyllanthoside 10.0
phosphorofluoridic acid 10.0
Phyllanthoside 10.0
2-(diethylamino)acetamide 10.0
bicyclo[3.1.0]hexan-3-one 9.4
2-butylhexanoic acid 9.4
Folex 9.4
bicyclo[3.1.0]hexan-3-one 9.0
1-(1-(2-thienyl)cyclohexyl)piperidine 9.0
Phyllanthoside 9.0
Isofenphos 8.6
C21H20O6 8.6
Phyllanthoside 8.6
C21H20O6 8.6
C21H20O6 8.6
C21H20O6 8.6
LY201116 8.6
C21H20O6 8.6
C21H20O6 8.4
Acepromazine maleate 8.4
L-2-Hydroxyglutaric acid 8.4
Hedamycin 8.4
Aprindine hydrochloride 8.4
C6H10O4 8.4
butanal oxime 8.2
Cinromide 8.0
SC-13504 8.0
C21H20O6 8.0
Ferbam 8.0
N-(hydroxymethyl)acrylamide 8.0
Talampanel 7.9
Quazepam 7.8
1-methyl-4-piperidinol 7.8
Kryptopyrrole 7.8
Streptomycin sulfate 7.7
Selfotel 7.6
3,3-dimethyl-2-butanol 7.6
Diphemanil 7.6
TOCP 7.6
Mipafox 7.5
GP 47779 7.5
N-(2,6-dimethylphenyl)benzamide 7.5
1,5-dibromopentane 7.4
Fosphenytoin 7.3
Diisopropyl 7.3
Colistin sulfate 7.3
H 44/68 7.2
2,6-piperazinedione 7.1
benzaldehyde semicarbazone 7.0
4-hydroxyphenylarsonic acid 7.0
1-phenyl-1,2,3,4-tetrahydroisoquinoline 7.0
Grayanotoxin I 7.0
1-phenyl-1,2,3,4-tetrahydroisoquinoline 7.0
1H-indazole-3-carboxylic acid 6.9
Trimeprazine 6.9
5-chloro-7-iodo-8-quinolinol 6.9
Penitrem A 6.8
Cyproheptadine hydrochloride 6.8
Norfenfluramine 6.8
Methacrylonitrile 6.8
Norfenfluramine 6.7
p-Nitrobenzoic acid 6.7
Trimethyltin chloride 6.6
Sulfobromophthalein 6.5
Normorphine 6.4
DFH 6.4
Pyrithiamine 6.4
reduced riboflavin 6.4
Dimetridazole 6.4
C9H11NO2 6.3
Phencyclidine 6.3
Hexachloroethane 6.2
1,3-Dinitrobenzene 6.2
Anexate 6.1
Interferon beta-1b 6.1
Clobazam 6.1
more...