Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004134 (ataxia)
 15,886 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MRI 1085
Sep 1007
Mol 573
axonal 561
She 409
frataxin 303
CSF 284
FMR1 255
SCA3 228
ataxin-3 216
SCA1 176
CACNA1A 171
ubiquitin 168
GABA 160
X-linked 158
SCA2 152
FMRP 151
SCA6 136
prion protein 134
prion 134
calcium channel 127
GAA 126
ataxin-1 93
ATP 92
Kv1.1 91
NMDA receptor 90
proteasome 88
ATM 87
Rec 84
glial fibrillary acidic protein 84
PCP 81
PrP 81
endoplasmic reticulum 80
dentatorubral-pallidoluysian atrophy 76
A-T 76
strabismus 73
spinocerebellar ataxia type 2 71
aprataxin 65
insulin 63
UTR 62
p53 62
SCA7 60
SACS 60
ATPase 59
tRNA 58
Rett syndrome 58
ATXN3 57
olfactory 54
lymphoid 53
POLG 50
glutamate receptor 49
creatine kinase 48
IgA 47
senataxin 46
Pol 45
L-type calcium channel 45
MIM 44
metabotropic glutamate receptor 44
B12 44
alpha-tocopherol transfer protein 44
hemoglobin 42
HLA 42
UBE3A 42
fragile X mental retardation protein 41
alpha-fetoprotein 41
sodium channel 40
huntingtin 40
cytochrome c oxidase 40
PKC-gamma 40
glutamic acid decarboxylase 39
MSA 39
acetylcholinesterase 38
amyloid precursor protein 38
GAD 37
voltage-gated potassium channel 36
albumin 36
Cav2.1 36
SCA8 35
Frataxin 35
calbindin 35
DNA polymerase gamma 34
NPC1 34
SCA17 34
NARP 34
histone 34
CD4 34
Spinocerebellar ataxia type 7 34
esterase 33
AR protein 33
vimentin 33
cytokine 33
cage 32
asymmetrical 32
ALS4 31
N-acetylaspartate 31
cystatin C 31
phosphatase 31
SCA5 31
14-3-3 31
helicase 31
thymus 30
telomeric 29
AOA 29
CA1 29
unknown function 29
ATXN1 29
DNA polymerase 28
myelin basic protein 28
FRDA 28
glycoprotein 28
DRPLA 28
14-3-3 protein 28
membrane-bound 28
GABA(A) receptor 28
por 28
caspase-3 28
PME 27
GBS 27
PRNP 27
synuclein 27
X-linked recessive 26
MERRF 26
neuropathy target esterase 26
transferrin 26
ACTH 26
SETX 25
TATA-binding protein 25
ATM protein 25
p62 25
MELAS 25
phosphodiesterase 25
KCNJ10 25
ATXN2 25
ITPR1 24
interferon 24
parvalbumin 24
aspartate aminotransferase 24
gut 24
ATP synthase 24
sit 24
ALS 24
DM1 23
fused 23
FGF14 23
pyruvate dehydrogenase 23
jerky 23
puratrophin-1 23
alkaline phosphatase 23
myelin-associated glycoprotein 23
Kir4.1 23
mTOR 23
NMR 23
FDG 23
APTX 23
CD8 23
TDP-43 23
FMR1 protein 22
novel gene 22
biotinidase 22
InsP3R1 22
more...
Disease
epilepsy 920
nystagmus 790
dementia 719
neuropathy 704
tumor 542
Friedreich's ataxia 526
depression 453
cancer 440
encephalopathy 436
Cerebellum 426
stroke 412
mental retardation 406
Machado-Joseph disease 402
mental retardation 400
apraxia 375
peripheral neuropathy 374
developmental delay 361
encephalitis 347
cognitive impairment 342
parkinsonism 336
diplopia 315
Huntington's disease 314
confusion 299
fits 292
multiple sclerosis 279
Parkinson's disease 277
Alzheimer's disease 271
polyneuropathy 260
deafness 259
Spinocerebellar ataxia 254
hemiparesis 253
coma 248
hydrocephalus 242
ATM 233
dysphagia 224
Miller Fisher syndrome 219
neurological disease 212
diabetes 210
migraine 202
fragile X syndrome 197
retinitis pigmentosa 189
amyotrophic lateral sclerosis 189
SCA1 176
movement disorder 176
Creutzfeldt-Jakob disease 175
optic atrophy 169
hypertension 169
blindness 169
Wernicke's encephalopathy 162
autism 162
SCA2 152
prolapse 147
Leigh syndrome 147
psychosis 146
vitamin E deficiency 145
myopathy 145
cardiomyopathy 136
muscular atrophy 133
schizophrenia 127
anemia 125
lactic acidosis 125
myelopathy 125
brain atrophy 121
hallucinations 121
sensory neuropathy 117
cerebellar syndrome 117
SCA6 117
spastic paraplegia 115
incontinence 113
meningitis 113
leukoencephalopathy 110
sensorineural hearing loss 107
Joubert syndrome 107
encephalomyelitis 107
hemiplegic migraine 105
neuroblastoma 105
Syndrome 105
disorientation 102
alcoholism 96
myoclonus epilepsy 94
immunodeficiency 94
Angelman syndrome 93
celiac disease 92
DM1 92
dyskinesia 91
thiamine deficiency 91
olivopontocerebellar atrophy 90
meningoencephalitis 88
lymphoma 86
cerebral palsy 86
malnutrition 85
carcinoma 83
PCP 82
genetic disorder 81
choreoathetosis 80
strabismus 77
vasculitis 77
facial palsy 76
status epilepticus 73
telangiectasia 73
hereditary ataxia 73
leukodystrophy 72
mitochondrial disease 72
virus infection 72
Rett syndrome 71
cold 71
scoliosis 70
Gerstmann 69
respiratory failure 68
Turner syndrome 68
rash 68
HIV 67
aphasia 67
pneumonia 64
siderosis 64
sensory disturbance 64
malabsorption 64
metastases 64
NPC 63
hypogonadism 62
Charcot-Marie-Tooth disease 61
West 61
SCA7 61
retinopathy 60
dysplasia 60
progressive supranuclear palsy 60
incontinence 57
mutism 57
breast cancer 56
infectious diseases 56
leukemia 53
astrocytoma 53
tetraplegia 53
rare disease 53
paraneoplastic syndrome 52
Niemann-Pick 52
neuronal ceroid lipofuscinosis 52
ischemia 51
PME 51
myelitis 51
cataract 51
meningioma 51
spongiform encephalopathy 51
spinal cord compression 51
autoimmune disease 51
scrapie 50
cytomegalovirus 50
HFA 49
mitochondrial myopathy 49
hypothyroidism 49
AIDS 48
adenocarcinoma 47
macrocephaly 47
Epstein 47
quadriparesis 47
aggression 47
metabolic disorder 46
delirium 46
Hashimoto's thyroiditis 46
subarachnoid hemorrhage 46
more...
Symptom
ataxia 15886
seizures 1522
tremor 1343
cerebellar ataxia 1129
weakness 1055
dysarthria 872
headache 679
myoclonus 587
ophthalmoplegia 547
vomiting 459
dystonia 449
spasticity 439
hypotonia 420
vertigo 415
dizziness 362
pain 361
paresis 352
sleepiness 251
nausea 233
lethargy 232
incoordination 220
diarrhea 196
fatigue 170
paresthesia 160
paraparesis 159
anorexia 143
anesthesia 140
chorea 136
ataxic gait 130
numbness 129
intention tremor 121
hypothermia 100
abnormal gait 96
agitation 88
dyspnea 87
hemiplegia 84
tinnitus 78
analgesia 75
insomnia 73
bradykinesia 69
clumsiness 67
torticollis 64
nausea and vomiting 59
blurred vision 58
memory loss 55
apathy 52
cough 51
hyperesthesia 50
hypertonia 45
tachypnea 44
pallor 42
athetosis 42
thinning 41
dysesthesia 38
collapse 37
constipation 37
myalgia 36
abdominal pain 35
neck pain 34
prostration 32
consciousness disturbance 32
loss of balance 30
hepatosplenomegaly 30
asthenia 29
emaciation 29
fasciculation 29
anosmia 28
polydipsia 28
Ataxic 28
tingling 28
twitching 26
hyperemesis gravidarum 26
respiratory distress 26
clonus 25
tonic-clonic seizure 23
syncope 23
splenomegaly 23
starvation 22
Ill 22
polyuria 21
spasm 21
hoarseness 21
functional recovery 20
arthralgia 19
photophobia 18
cachexia 18
hepatomegaly 18
abiotrophy 17
nasal discharge 16
Sedation 16
personality change 16
back pain 15
colic 15
cyanosis 15
discomfort 14
muscle rigidity 14
erythema 13
stridor 13
hypalgesia 13
neuralgia 12
abnormal breathing 12
giddiness 12
Sensory ataxia 12
discomfort 12
giddiness 12
staggering gait 12
regurgitation 11
blepharospasm 11
chest pain 11
lightheadedness 11
facial pain 11
asterixis 11
decreased appetite 10
neck stiffness 10
muscle stiffness 10
urinary frequency 9
labored breathing 9
drooling 9
dysuria 9
meningism 9
muscle cramps 9
neurological disability 8
Spastic 8
astasia 8
forgetfulness 8
partial seizure 7
retching 7
distraction 7
bloating 7
impaired motor coordination 7
excessive sweating 7
shortness of breath 7
low back pain 7
loss of taste 7
Neurologic symptoms 6
chronic cough 6
catatonia 6
sneezing 6
Involuntary Movement 6
frequent urination 6
otalgia 6
Decreased activity 6
Motor dysfunction 6
hyperemesis 5
Limb ataxia 5
flushing 5
sore throat 5
facial droop 5
cancer pain 5
Bell's phenomenon 5
lassitude 5
Lhermitte's sign 5
Limb weakness 4
rhinorrhea 4
Truncal ataxia 4
Neuropathic pain 4
hypersomnia 4
snoring 4
visual hallucination 4
hemoptysis 4
more...
Drug
CSF 285
vitamin E 144
PCP 81
lysine 43
Vitamin E 38
Ethanol 31
DFP 30
caffeine 26
Dermatol 22
DM1 21
Gabapentin 20
ROS 15
CTA 15
ADM 13
Vitamin B12 12
Phenytoin 12
9-THC 12
Posture 12
AGG 11
Cardiovasc 10
Pregabalin 9
Spectrum 9
NADH 9
Frontal 9
Spectrum 8
ampicillin 8
Ranitidine 8
Vitamin B 8
TTC 8
CTX 7
ABC 7
Idebenone 6
ascorbate 6
Rituximab 6
Azithromycin 6
Monensin 6
Sodium valproate 6
Nephron 6
Asn 5
Methylprednisolone 5
Parkin 5
Tocopherol 5
Monit 5
Zmax 5
Parkin 5
lactose 5
PTH 5
Metrizamide 5
Swainsonine 5
niacin 4
Glutathione 4
Fosphenytoin 4
IFN-gamma 4
GVG 4
TMS 4
Ganciclovir 4
Prednisolone 4
Miglustat 4
ENT 4
Piracetam 4
Riboflavin 4
Scopolamine 4
Sinemet 4
MRC 4
Brotizolam 4
ROC 4
Clonidine 3
CAM 3
Duloxetine 3
Flunitrazepam 3
Apomorphine 3
Abecarnil 3
IL-2 3
Domperidone 3
Alanine 3
Zonisamide 3
HCH 3
THF 3
Prednisone 3
Carbidopa 3
Diphenhydramine 3
Leaf 3
Lasalocid 3
Heme 3
Mutagen 3
Atropine 3
BH4 3
Fluorescein 3
Moxidectin 3
CCL 3
Nabilone 3
MAP 2
Perphenazine 2
CTT 2
HCG 2
Diamox 2
citric acid 2
Corn oil 2
Iopamidol 2
pyridoxal phosphate 2
Sumatran 2
Thyroglobulin 2
Chantix 2
Bortezomib 2
Propofol 2
Natalizumab 2
Indocyanine green 2
Medetomidine 2
ICI 2
Paraffin 2
Fluconazole 2
Itraconazole 2
Atipamezole 2
Orphan 2
Gastro 2
Tacrolimus 2
FAD 2
Bayer 2
Taxol 2
Ziconotide 2
CDP 2
Ganaxolone 2
Histamine 2
DBS 2
Camp 2
EPA 2
TRM 2
Acacia 2
Lioresal 1
Rolipram 1
Gel 1
CPR 1
Zofran 1
Limonene 1
Codeine 1
Lisuride 1
Muzolimine 1
TAT 1
VCR 1
Sulthiame 1
Clodronate 1
Alliance 1
Nitazoxanide 1
Dextrose 1
Vitamin K 1
Stiripentol 1
DDAVP 1
Valdecoxib 1
Simvastatin 1
DPA 1
Oxaliplatin 1
Gamma globulin 1
Etoposide 1
LMWH 1
Quinine, 1
Epigallocatechin 1
L-Ser 1
Gadobenate dimeglumine 1
Theophylline 1
CIA 1
more...
Enzyme
proteasome 96
PCP 81
ATPase 73
protein kinase 63
acetylcholinesterase 60
creatine kinase 53
complex I 44
DNA polymerase 40
hexosaminidase 37
cholinesterase 37
pyruvate dehydrogenase 37
cytochrome oxidase 35
protein kinase C 35
catalase 34
mitogen-activated protein kinase 31
aspartate aminotransferase 31
neuropathy target esterase 30
phosphodiesterase 29
ERK 28
RNA polymerase 27
ATP synthase 27
succinate dehydrogenase 25
neuraminidase 24
ceruloplasmin 23
pyruvate dehydrogenase 23
pyruvate dehydrogenase 23
alkaline phosphatase 23
biotinidase 22
superoxide dismutase 22
caspase-3 21
tyrosine hydroxylase 21
beta-galactosidase 20
alanine aminotransferase 18
thyroid peroxidase 18
aconitase 17
transglutaminase 16
enolase 16
lactate dehydrogenase 15
topoisomerase 15
carbonic anhydrase 15
DNA ligase 15
DNA ligase 15
topoisomerase 14
choline acetyltransferase 13
transketolase 13
calcineurin 13
reverse transcriptase 13
gamma-glutamyl transpeptidase 12
histone acetyltransferase 12
glutamate dehydrogenase 11
peroxidase 11
glutamate dehydrogenase 11
CYP27A1 11
glutathione peroxidase 10
acid phosphatase 10
m-AAA protease 10
proteinase K 10
ACS 9
TPP 9
polynucleotide kinase 9
monoamine oxidase 9
PARP 9
ACE 9
glutamate dehydrogenase 9
P-glycoprotein 9
phosphomannomutase 9
endonuclease 8
alpha-ketoglutarate dehydrogenase 8
phospholipase C 8
RNase 8
phosphatidylinositol 3-kinase 8
succinic semialdehyde dehydrogenase 8
tissue plasminogen activator 8
RNase 8
pantothenate kinase 8
luciferase 8
diaphorase 7
ornithine transcarbamylase 7
transcriptase 7
focal adhesion kinase 7
glucocerebrosidase 7
CaMKII 7
sulfatase 7
sialidase 7
tripeptidyl peptidase 6
GABA transaminase 6
citrate synthase 6
AST 6
phytanoyl-CoA hydroxylase 5
methionine synthase 5
methylenetetrahydrofolate reductase 5
NOS 5
diaphorase 5
BMT 5
NO synthase 5
VOR 5
AMPK 5
guanylate cyclase 5
protein phosphatase 2A 5
methylenetetrahydrofolate reductase 5
ubiquitin-protein ligase 5
mevalonate kinase 5
MEK 5
methionine synthase 5
sorbitol dehydrogenase 4
isopeptidase 4
kinesin 4
PDH 4
glucosylceramide synthase 4
TOR 4
glutaminase 4
alcohol dehydrogenase 4
aspartyl-tRNA synthetase 4
PRPP synthetase 4
CPR 4
pyruvate carboxylase 4
cdc2 4
adenosine deaminase 4
GSK 4
carboxypeptidase Y 4
lipase 4
GCA 4
AMP-activated protein kinase 4
TPP 4
ALA synthase 4
3'-phosphatase 4
alanyl-tRNA synthetase 4
APC 4
glutamate decarboxylase 3
STR 3
LasR 3
glutathione reductase 3
glutathione synthetase 3
pyruvate decarboxylase 3
granzyme B 3
pyruvate kinase 3
CD10 3
demethylase 3
arginase 3
Alternating 3
mu-calpain 3
glutathione S-transferase 3
sialyltransferase 3
sialyltransferase 3
glucose-6-phosphate dehydrogenase 3
SCP 3
Lod 3
sialyltransferase 3
galactocerebrosidase 3
fumarase 3
cystathionine beta-synthase 3
phosphoinositide 3-kinase 3
IKK 3
adenosine deaminase 3
arylsulfatase A 3
beta-glucuronidase 3
glutamine synthetase 3
ferrochelatase 3
trehalase 3
CYP7B1 3
more...
Compound
Dec 1039
DNA 1000
Clin 881
calcium 354
His 286
sodium 225
ethanol 205
water 201
glucose 194
iron 189
potassium 180
glutamate 175
GABA 163
oxygen 161
GABA 160
glutamine 145
phosphate 114
copper 93
ATP 92
gamma-aminobutyric acid 88
Neuronal 86
PCP 81
leucine 70
urea 68
NMDA 67
arginine 67
lysine 63
methionine 61
ammonia 59
serine 51
GM1 51
sulfate 46
galactose 45
valine 44
Vitamin E 44
tyrosine 43
A 3 43
nitrogen 43
alanine 43
mercury 42
coenzyme Q10 41
acetate 41
cysteine 41
creatinine 41
acrylamide 40
hydrogen 40
tryptophan 40
Thiamine 39
zinc 38
tryptophan 36
tryptophan 35
tryptophan 35
salt 34
5-HT 34
nitric oxide 33
CO2 31
threonine 31
N-acetylaspartate 31
noradrenaline 30
selenium 30
AMPA 30
CAA 29
GM2 28
proline 27
caffeine 27
PEG 26
ACTH 26
AMP 25
manganese 24
acetic acid 24
PEG 23
5-hydroxytryptophan 23
Ile 23
Diazepam 22
Phe 22
DBA 21
DBA 21
DBA 21
TTP 21
toluene 21
CAT 20
Valproic acid 20
CAT 20
CAT 20
bromide 20
Neurotol 20
phosphorus 20
Cardiol 19
nicotinamide 19
ammonium 19
A 1 19
Ketamine 19
piperidine 18
piperidine 18
vitamin D 17
isoleucine 17
TRH 17
CPP 17
Phencyclidine 17
NAD 17
CPP 17
isoleucine 17
glutamic acid 16
Coenzyme Q10 16
DPH 16
Isoproterenol 16
L-DOPA 16
ADP 16
ADP 16
ADP 16
Asp 15
pyridine 15
SDS 15
pyrimidine 15
HCl 15
pyrimidine 15
Acetazolamide 15
homocysteine 15
glycerol 14
TPP 14
ubiquinone 14
ANA 14
NAD 14
silver 14
CoQ 14
iodine 14
TBP 14
PAS 14
ANA 14
TBP 14
asparagine 13
DTPA 13
hydroxyindoleacetic acid 13
cyanide 13
MPTP 13
nitrate 13
aspartic acid 13
Topiramate 13
A 71 13
Cereb 13
Clonazepam 12
cAMP 12
Lamotrigine 12
NH2 12
TPP 12
TNF 12
AAA 12
oxalate 12
Lithium 12
Diisopropyl 11
NBQX 11
propylene glycol 11
propylene glycol 11
Glutamate 11
COX 11
fluorine 11
N2O 11
Gly 11
T10 11
piperazine 11
more...