Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004134 (ataxia)
 15,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Effects of Chlorpromazine (CPZ), Haloperidol (HLP), Pentobarbital (PTB), and Diazepam (DZP) upon thresholds of the hypothalamically elicited rage response, i.e., directed attack and treat responses, were studied in chronic cats. All these drugs elevated the directed attack thresholds. CPZ and HLP elevated also the threat response thresholds and produced ataxia, but DZP did not show these effects. From these results, it is suggested that CPA and HLP suppressed the amygdalo-ventromedial hypothalamic nuclear and cerebellar functions and DZP suppressed the afferent pathway of the direct attack. PTB showed intermediate effects between the above two groups.
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PMID:Effects of psychotropic drugs upon the hypothalamic rage response in cats. 102 47

Vestibular symptoms have been rarely described in cerebellopontine angle epidermoid tumours. We report a case of CPA epidermoid tumour presenting with subacute onset of vestibular symptoms such as vertigo, gait ataxia, and nystagmus masquerading as acute vestibular neuritis or central vertigo. The vestibular symptoms disappeared after excision of the tumour.
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PMID:Cerebellopontine angle epidermoid tumour presenting with bilateral gaze nystagmus. 1856 37