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Query: UMLS:C0004134 (ataxia)
 15,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An adolescent presented with headache and projectile vomiting and showed ataxia, dysarthia and nystagmus with normal cognition. A diagnosis of acute cerebellitis was made on the basis of computed tomography and magnetic resonance imaging findings. He developed seizures and had a rapid downhill course with death at 48 hours after admission. Clinically, patients of acute cerebellitis present with fever, nausea, headache and altered sensorium with cerebellar symptoms. Inflammation of the cerebellum compresses the brain stem and induces mental alterations. It is a rare pathology developing due to an infectitious cause, post-infectitious or post vaccination etiology. Many times it is not possible to identify the causative agent. Cerebellitis can be mild where recovery occurs in few weeks and no abnormalities are seen on diagnostic imaging studies. On the other end, severe cases have focal neurological deficits, altered consciousness, raised intracranial pressure and abnormal neuroimaging. Treatment should be tailored to individual needs according to presentation, severity, and etiology. We discuss clinical features, diagnosis and management of acute cerebellitis which is an important cause of acute cerebellar functional disorder in childhood.
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PMID:Catastrophic Cerebellitis in an adolescent: A Case Report. 3099 18

Cerebellar liponeurocytoma is a rare oncological entity, and the knowledge about the treatment and outcome of these rare tumors is still evolving. Very few cases have been described in literature. We report a middle-aged male who presented with raised intracranial pressure features and gait ataxia. His imaging features revealed classical features of liponeurocytoma in cerebellar vermis, with abundant fat component evident in both computed tomography and magnetic resonance imaging. He underwent resection of the lesion and has been asymptomatic for 4 years. This report describes the classical radiological and immunohistochemical features of this rare entity with favorable outcome and reviews the existing literature.
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PMID:Cerebellar Liponeurocytoma: A Rare Fatty Tumor and its Literature Review. 3100 Oct 37

Opisthotonus as a presenting feature in neurosurgical patients is rare, with few reports describing such presentations. Only four reports of opisthotonos secondary to posterior fossa mass were identified. An unclear pathophysiology, and broad aetiology contribute to clinical misdirection. While posterior fossa lesions commonly present with signs of raised intracranial pressure, or cerebellar dysfunction, this case describes the presentation of an infant with opisthotonic posturing, ataxia and autonomic dysfunction secondary to a large pilocytic astrocytoma. Despite initial treatment of hydrocephalus, opisthotonus only resolved with complete surgical resection of the posterior fossa mass. At follow-up, the child remains well and without signs of hypertonicity or other signs or symptoms. Presentations involving opisthotonus are rare, and active exclusion of posterior fossa pathology is necessary. In this case, urgent surgical resection allowed for a positive patient outcome. Description of such a case may contribute to understanding of similar presentations in the neurosurgical context.
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PMID:Posterior fossa pilocytic astrocytoma presenting with opisthotonus in an infant - A case report. 3135 29


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