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Query: UMLS:C0004134 (ataxia)
 15,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The diagnosis of meningo-radiculitis of unknown etiology was posed on a adult Caucasian male patient, based on clinical and biological symptoms offered since 1991, February (CSF: lymphocytic with hyperproteinosis). The patient had stayed in different bilharzia endemic zones. Confronted with a lack of improvement, even an aggravation and facing an appearance of a pyramidal symptom of the limbs, mostly at left, with ataxia preventing walking, one admitted the patient several times to do biological and radiological tests. They confirmed the troubles at the level of the CSF, already above mentioned; the MRI showed a hypersignal at the low dorso-lumbar level and at the terminal cone without any sign of tumoral processus, associated to an abnormal contrast at the level of meninges. All of that revealed a significant aspect of a meningo-myelo-radiculitis. In front of the various negative sero-bacteriological, viral, parasitic test, of the unresults of the research of any systemic symptom, one decided to perform a neurosurgical intervention to get a biopsy. So was revealed the presence of ovoid elements PAS+with a lateral spur and parasitic aspect. Consequently the diagnosis of bilharziosis was established. A cure of Praziquantel has been prescribed: 3 tablets/day for 10 days, and four more cures at an interval of one month, all of them associated to a long term corticotherapy. Any diminution of the dosis entailed an increase of the painful symptomatology. Because of the perennial posterior cordal painful symptom, the patient has shown a depressive reaction.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Developmental aspects of a bilharziasis caused by Schistosoma mansoni]. 813 34

Human toxocariasis has been reported to cause a broad spectrum of neurological syndromes, including encephalitis, meningitis and meningo-radiculitis. Nevertheless, cerebral infection by Toxocara may go undiagnosed due to its rarity, elusive symptoms and lack of availability of appropriate testing. We report the case of a 54-year-old man who presented with abdominal pain and paralytic ileus approximately 3 weeks after having eaten raw snails (a folk remedy for peptic ulcer). Three weeks later, marked eosinophilia ensued, associated with mental clouding, nystagmus, diplopia, peripheral limbs ataxia, urinary retention, slackened deep tendon reflexes, arthralgias and myalgias. Cerebrospinal fluid (CSF) examination demonstrated an eosinophilic meningitis, and Toxocara canis cerebral infection was diagnosed by positive serology and by the detection of T. canis DNA in the CSF. The patient made a full recovery following treatment with albendazole and corticosteroids. Physicians should be aware of this rare presentation of toxocariasis, whose diagnosis is, today, facilitated by molecular biology techniques. A history of ingestion of raw snails may alert the clinician to consider the possibility of such an uncommon condition.
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PMID:Toxocara encephalitis presenting with autonomous nervous system involvement. 2299 85

Angiostrongylus Eosinophilic Meningitis is caused by human infection with larvae of the rat lungworm, Angiostrongylus cantonensis. The clinical presentation includes a spectrum of disease, from meningitis through radiculitis, cranial nerve abnormalities, ataxia, encephalitis, coma, and rarely death. The condition is diagnosed by recognizing the triad of: the clinical syndrome, eosinophils in the cerebrospinal fluid or blood, and exposure history. A history of eating raw or poorly cooked snails is classic, but ingestion of other intermediate hosts or unwashed produce (such as lettuce) harboring hosts is not uncommon. Several serologic tests exist but none has yet been fully validated. There is good evidence that a 2 week course of high dose corticosteroids shortens the duration and severity of symptoms. There is somewhat weaker evidence that albendazole reduces symptoms. The combination of prednisolone and albendazole is being used more commonly for treatment. Some suggestions for future research are given.
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PMID:Clinical aspects of eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis, the rat lungworm. 2390 82