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Query: UMLS:C0004134 (ataxia)
 15,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Maedi-visna virus infection in a flock of sheep in Scotland was associated with respiratory disease, neurological disease, mastitis and lameness. The major clinical signs were dyspnoea (particularly on exercise), progressive fore- and hindlimb ataxia and balance defects, mammary induration and multilimb lameness, occasionally with enlarged carpal joints. Pathological examinations revealed lesions in the lungs, central nervous system, mammary glands and joints which were consistent with those induced by maedi-visna virus. The was no clinical or pathological evidence of concurrent sheep pulmonary adenomatosis, and pulmonary bacterial infections, when they occurred, were superimposed on the lesions due to maedi-visna virus.
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PMID:Clinicopathological investigation of primary, uncomplicated maedi-visna virus infection. 838 91

The nervous form of Maedi-Visna (MV) infection was diagnosed in four lambs aged 4 and 6 months, belonging to three different Assaf flocks that were managed intensively for milk and meat production. The animals presented with hindleg ataxia that rapidly progressed to complete recumbency. Lesions consisted of a moderate to severe non-purulent encephalitis affecting mainly the cerebellar peduncles. MV virus was demonstrated in the damaged tissues by immunohistochemistry and polymerase chain reaction. The investigation demonstrated that the clinical presentation of the nervous form of MV which is reported to occur in adult sheep can also be observed in young animals.
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PMID:Diagnosis of clinical cases of the nervous form of Maedi-Visna in 4- and 6-month-old lambs. 1715 Mar 88