Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003969 (vitamin C deficiency)
 625 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
collagen 97
Sep 29
microsomal 17
cytochrome P-450 17
endoplasmic reticulum 14
B12 13
osteogenic 12
ferritin 12
alkaline phosphatase 11
gut 8
proteoglycan 8
superoxide dismutase 6
collagenase 6
insulin-like growth factor 6
acid phosphatase 6
insulin 6
elastin 6
SVCT2 5
lipopolysaccharide 5
IGF-I 5
NADPH 5
albumin 5
HDL 5
polypeptide 4
interferon 4
ACTH 4
NADPH-cytochrome P-450 reductase 4
reductase 4
ceruloplasmin 4
SOD 4
type I collagen 4
glutathione reductase 4
glutathione peroxidase 4
glucosamine 4
GSH 4
rat) 4
cytokine 4
transferrin 3
cytochrome 3
serum albumin 3
flavin-containing monooxygenase 3
tyrosine hydroxylase 3
galactosamine 3
catalase 3
Mol 3
haptoglobin 3
carp 3
SDS 3
IL-8 3
Gen 3
C-reactive protein 3
chronic renal failure 3
heme oxygenase-1 3
brush border 3
lymphoid 3
growth hormone 2
Ferritin 2
defensin 2
lipoprotein lipase 2
LCAT 2
transketolase 2
ATPase 2
transthyretin 2
ZO-2 2
IL-6 2
regucalcin 2
Occludin 2
NF-E2-related factor 2 2
APP 2
NADH 2
type II collagen 2
hSVCT1 2
She 2
P40 2
apolipoprotein A-I 2
ribosomal protein S6 kinase 1 2
membrane protein 2
leucine aminopeptidase 2
FAD 2
insulin-like growth factor-I 2
IL-11 2
erythropoietin 2
p65 2
apoE 2
osteocalcin 2
ATP 2
claudin-12 2
glycoprotein 2
glucose-6-phosphatase 2
p38 mitogen-activated protein kinase 2
NAD 2
manganese superoxide dismutase 2
hemoglobin 2
SVCT1 2
P35 2
MMP-2 2
PSEN1 2
cytochrome P450 2
osteopontin 2
TET2 2
spermatozoa 2
interleukin-6 2
butyrobetaine 2
Fas ligand 2
brain) 2
4E-BP1 2
MMP-9 2
Bcl-2 2
alpha-glucosidase 2
lysozyme 2
VIII 2
IGFBP-1 2
aspartate aminotransferase 2
tumor necrosis factor 2
tropoelastin 2
Apaf-1 2
HMG-CoA reductase 2
5-hydroxytryptamine 2
caspase-3 2
inhibitor of apoptosis 2
aromatase 2
histone 2
core protein 2
HDL2 2
membrane-bound 2
cytochrome c 1
Rec 1
IGF binding 1
Protein A 1
IRS-1 1
glutaredoxin 1
lactoferrin 1
epididymal 1
ELK1 1
Erythropoietin 1
thioredoxin reductase 1
beta-glucuronidase 1
SLC23A2 1
Hop 1
glial fibrillary acidic protein 1
San 1
dopamine beta-hydroxylase 1
pyruvate dehydrogenase 1
IGFBP-3 1
IGF-binding protein 1
prothrombin 1
GLUT2 1
non-functional 1
3 beta-hydroxysteroid dehydrogenase 1
lysyl oxidase 1
hexosaminidase A 1
stomatin 1
acetylcholinesterase 1
fruitless 1
presenilin 1 1
Mem 1
ugd 1
IL-15 1
ACG 1
olfactory 1
AMP 1
PG-Lb 1
bone morphogenetic protein 1
CYP2E1 1
reserved 1
SCN 1
alpha1-acid glycoprotein 1
4E-BP2 1
6-phosphogluconate dehydrogenase 1
sodium pump 1
transcobalamin II 1
IL-17D 1
DDR 1
RANTES) 1
GDP 1
cathepsin D 1
p52 1
PHD2 1
GSTM1 1
twist 1
heme-binding protein 1
NRC 1
IL-4 1
API 1
lysyl hydroxylase 1
IKK 1
period 3 1
Insulin-like growth factor I 1
IL6 1
NADP 1
glutamate dehydrogenase 1
interleukin 10 1
myeloperoxidase 1
MRI 1
myelin basic protein 1
p53 1
ABC 1
methionine synthase 1
cage 1
CD4 1
ACS 1
matrix Gla protein 1
Hepcidin 1
aldo-keto reductase 1
MKK6 1
IGF-II 1
adenylate cyclase 1
MCT1 1
calcium channel 1
LPS 1
Acid phosphatase 1
nitric oxide synthase 1
Lipoprotein lipase 1
Lp(a) 1
prolyl 4-hydroxylase 1
1alpha(OH)ase 1
lacrimal 1
periaxin 1
GRP78 1
hemochromatosis 1
tartrate-resistant acid phosphatase 1
insulin receptor substrate 1
protein disulfide isomerase 1
aldolase B 1
amyloid precursor protein 1
substance P 1
Haptoglobin 1
ANOVA 1
P450scc 1
IL-10 1
PDF 1
apolipoprotein A1 1
TNF 1
thrombin 1
insulin-like growth factor 1 1
VEGF 1
chemokine 1
binding peptide 1
glyceraldehyde-3-phosphate dehydrogenase 1
aconitase 1
threonine 1
proliferating cell nuclear antigen 1
ASC 1
UDP-glucuronyltransferase 1
iron regulatory protein 1 1
delta-aminolevulinic acid dehydratase 1
osteonectin 1
IFN 1
esterase 1
AKT 1
autosomal recessive) 1
endothelial nitric oxide synthase 1
cytochrome b5 1
apolipoprotein E 1
GSTP1 1
GLUT1 1
prolactin 1
tap 1
lamp 1
c-Jun 1
TNF-alpha 1
P450 1
glucose-6-phosphate dehydrogenase 1
Aromatase 1
aldehyde reductase 1
TET1 1
EGF 1
eNOS 1
transferrin receptor 1
GSTT1 1
matrix metalloproteinase 1
Yes 1
cytochrome c oxidase 1
monocyte chemotactic protein 1
ADAMDEC1 1
SLC23A1 1
alcohol dehydrogenase 1
fructokinase 1
Laminin 1
chondroitinase 1
cytochrome b 1
protein kinase B 1
Maltase 1
cyclooxygenase 1
interleukin-2 1
hemopexin 1
beta-endorphin 1
JAMA 1
calbindin 1
AAS 1
chorionic gonadotropin 1
ferrochelatase 1
Prolyl hydroxylase 1
prolidase 1
proton pump 1
fibronectin 1
transforming growth factor-beta 1
NMR 1
antithrombin 1
PFC 1
hedgehog 1
vascular endothelium 1
Galactosyltransferase 1
CYP1A2 1
period 2 1
proline hydroxylase 1
lipase 1
proline-rich 1
peroxisome proliferator-activated receptor 1
COX-2 1
GRP94 1
glucose transporter 1
DNA methyltransferase 1
TET3 1
UDP-glucuronic acid 1
myosin light chain kinase 1
gamma-butyrobetaine hydroxylase 1
diamine oxidase 1
PDGF 1
IGFBP-2 1
more...
Disease
vitamin C deficiency 625
scurvy 207
malnutrition 42
hypovitaminosis 26
anemia 26
cancer 22
atherosclerosis 17
purpura 13
gingivitis 12
Disorder 11
rash 11
depression 10
diabetes 10
hypertension 9
tumor 9
hypercholesterolemia 8
hyperkeratosis 8
vasculitis 8
petechiae 8
thiamine deficiency 7
sepsis 7
infectious diseases 7
alcoholism 7
osteoporosis 7
mental illness 7
pneumonia 7
autism 6
osteomalacia 6
coronary heart disease 6
iron deficiency 6
plaque 6
beriberi 6
leukemia 6
vitamin A deficiency 6
vitamin E deficiency 6
cardiovascular disease 6
sepsis 5
iron overload 5
cerebral palsy 5
cold 5
periodontal disease 5
rare disease 5
anorexia nervosa 5
pulmonary hypertension 5
rickets 5
alcohol abuse 4
pellagra 4
GSH 4
Alzheimer's disease 4
obesity 4
heart failure 4
gastritis 4
aqueous humor 4
cataract 4
chronic renal failure 4
vitamin D deficiency 4
gallstones 4
malabsorption 4
SDS 3
hemorrhagic diathesis 3
folate deficiency 3
dysplasia 3
oxalosis 3
Crohn's disease 3
postherpetic neuralgia 3
gastric cancer 3
peptic ulcer 3
carcinogenesis 3
osteomyelitis 3
chronic disease 3
hyperglycemia 3
hyperhomocysteinemia 3
deep vein thrombosis 3
renal disease 3
tumor growth 3
hyperlipidemia 3
myopathy 3
stroke 3
kwashiorkor 3
hyperparathyroidism 3
renal osteodystrophy 3
synovitis 2
B-cell lymphoma 2
wasting 2
proptosis 2
thrombocytopenia 2
Down syndrome 2
neuroblastoma 2
liver disease 2
arteriosclerosis 2
irritable bowel syndrome 2
Barlow 2
dyschondroplasia 2
abruptio placentae 2
keratosis 2
periodontitis 2
lens opacity 2
metabolic disorder 2
myocardial ischemia 2
macular degeneration 2
gout 2
cystic fibrosis 2
thalassemia major 2
melanoma 2
megaloblastic anemia 2
eating disorder 2
tyrosinemia 2
myelodysplastic syndrome 2
vitamin B6 deficiency 2
iron deficiency anemia 2
hypothyroidism 2
enteritis 2
dysphagia 2
porphyria cutanea tarda 2
HDL2 2
arthritis 2
keratosis 2
respiratory failure 2
bone disease 2
stomatitis 2
Albert 2
leg ulcers 2
sicca syndrome 2
ulcerative colitis 2
tooth loss 2
Plaque 2
rheumatoid arthritis 2
Testes 2
scoliosis 2
riboflavin deficiency 2
marasmus 2
anxiety disorders 2
xerostomia 2
worms 2
confusion 2
cornea 2
HDL3 2
fructosuria 1
gastrointestinal disease 1
hemochromatosis 1
cheilosis 1
hyperopia 1
aggression 1
Syndrome 1
Helicobacter pylori infection 1
hyperostosis 1
pulmonary edema 1
Zinc deficiency 1
failure to thrive 1
acromegaly 1
osteosclerosis 1
agranulocytosis 1
myositis 1
enterocolitis 1
Age-related macular degeneration 1
prediabetes 1
chronic pain 1
Muscle degeneration 1
fibrosarcoma 1
HSP 1
sinus tachycardia 1
coronary thrombosis 1
Endothelial dysfunction 1
Schamberg's disease 1
gum disease 1
atherosclerotic cardiovascular disease 1
Pyridoxine deficiency 1
Pulmonary arterial hypertension 1
OHD 1
Sjogren's syndrome 1
hydrocephalus 1
Cornea 1
colitis 1
epilepsy 1
breast cancer 1
Growth failure 1
cardiac tamponade 1
septic arthritis 1
parkinsonism 1
disc degeneration 1
tetanus 1
thalassemia 1
degenerative disc disease 1
metastases 1
Sweet 1
inflammatory bowel disease 1
hiatal hernia 1
motor neuron disease 1
epiphysis 1
diabetic foot ulcers 1
influenza 1
alcoholic cirrhosis 1
glaucoma 1
compartment syndrome 1
photosensitivity 1
dementia 1
spondyloarthropathy 1
fatty liver 1
pneumothorax 1
polio 1
essential hypertension 1
glossitis 1
aggressiveness 1
G6PD deficiency 1
West 1
dentinogenesis imperfecta 1
duodenal ulcer 1
rheumatism 1
phobia 1
porphyria 1
disorientation 1
gingivostomatitis 1
coagulopathy 1
regional pain syndrome 1
ischemia 1
rheumatic fever 1
lymphopenia 1
dysentery 1
epulis 1
primary hyperparathyroidism 1
AAS 1
platelet disorder 1
hypoglycemia 1
amyotrophic lateral sclerosis 1
connective tissue disease 1
retinopathy 1
tobacco abuse 1
thrombocytopenic purpura 1
methylmalonic acidemia 1
emotional disorder 1
Bateman 1
atopic dermatitis 1
viral hepatitis 1
dyspepsia 1
hypoparathyroidism 1
graft-versus-host disease 1
HIV 1
nutritional disorder 1
hereditary fructose intolerance 1
Autism spectrum disorder 1
compulsion 1
hypophosphatasia 1
virus infection 1
arthropathy 1
macrocytic anemia 1
lichen planus 1
malaria 1
vitamin B deficiency 1
joint effusion 1
cerebral thrombosis 1
chronic obstructive pulmonary disease 1
tyrosinosis 1
vitamin K deficiency 1
Brown tumor 1
acute osteomyelitis 1
developmental delay 1
myocardial infarction 1
SEM 1
refractory anemia 1
pulmonary embolism 1
Parkinson's disease 1
seminal vesicles 1
acrodermatitis enteropathica 1
sickle cell disease 1
gastrointestinal infection 1
xerosis 1
metabolic syndrome 1
pyoderma gangrenosum 1
oral candidiasis 1
Primary osteoporosis 1
anaphylaxis 1
leukopenia 1
dyslipidemia 1
von Willebrand disease 1
cheilitis 1
hepatitis A 1
measles 1
edentulous 1
paranoid personality disorder 1
chronic hepatitis 1
OCD 1
Ehlers-Danlos syndrome 1
adrenal insufficiency 1
hepatitis C 1
hepatocellular carcinoma 1
Gingival hypertrophy 1
aphthous stomatitis 1
uterus 1
genetic hypertension 1
cardiac overload 1
protein deficiency 1
congenital hypothyroidism 1
trismus 1
type 2 diabetes 1
degenerative disease 1
Raynaud 1
Cornea 1
Raynaud's phenomenon 1
periostitis 1
cytomegalovirus 1
gangrene 1
osteodystrophy 1
premature rupture of membranes 1
pruritus 1
heart disease 1
hyperuricemia 1
multiple myeloma 1
atrophic gastritis 1
cholera 1
muscular atrophy 1
AIDS 1
dysbasia 1
thrombocytosis 1
gastroenteritis 1
xerophthalmia 1
gastroesophageal reflux disease 1
Bury 1
esophagitis 1
epididymis 1
coronary artery disease 1
more...
Symptom
pain 15
fatigue 14
weakness 8
anorexia 7
inanition 5
arthralgia 5
collapse 5
bone pain 4
starvation 4
lethargy 4
Ill 4
dyspnea 3
seizures 2
myalgia 2
limb pain 2
exertional dyspnea 2
asthenia 2
erythema 2
diarrhea 2
anesthesia 2
chest pain 2
back pain 1
abdominal pain 1
menometrorrhagia 1
thinning 1
tremor 1
pallor 1
knee pain 1
halitosis 1
exhaustion 1
Localized pain 1
nausea and vomiting 1
sleepiness 1
hypotonia 1
shortness of breath 1
tingling 1
overweight 1
ataxia 1
hepatomegaly 1
cardiovascular impairment 1
nausea 1
decreased appetite 1
syncope 1
Drug
ascorbate 343
vitamin E 17
Dermatol 8
lysine 8
Dial 5
niacin 3
Vitamin A 3
Vitamin B12 2
Monit 2
NADH 2
Glutathione 2
IL-11 2
FAD 2
Ascorbic Acid 2
pyridoxal phosphate 2
BH4 1
Iron dextran 1
THF 1
Diethylpropion 1
Camp 1
Epoetin alfa 1
Mazindol 1
Histamine 1
Lycium fruit 1
caffeine 1
Indomethacin 1
ampicillin 1
ABC 1
Vitamin E 1
Gel 1
Epoetin alfa 1
Enzyme
GLO 13
alkaline phosphatase 11
superoxide dismutase 8
collagenase 6
acid phosphatase 6
demethylase 5
ceruloplasmin 4
glutathione peroxidase 4
glutathione reductase 4
tyrosine hydroxylase 3
flavin-containing monooxygenase 3
alpha-glucosidase 3
catalase 3
prolyl hydroxylase 3
heme oxygenase 3
CPR 3
invertase 3
sucrase 3
glucose-6-phosphatase 2
transketolase 2
NADPH oxidase 2
aspartate aminotransferase 2
gamma-butyrobetaine hydroxylase 2
lipoprotein lipase 2
acetylcholinesterase 2
succinate dehydrogenase 2
caspase-3 2
leucine aminopeptidase 2
lysozyme 2
NADPH oxidase 2
papain 2
ATPase 2
ECH 2
hexosaminidase 2
alcohol dehydrogenase 2
beta-glucosidase 1
alpha-mannosidase 1
lactonase 1
creatine kinase 1
6-phosphogluconate dehydrogenase 1
cathepsin D 1
aldose reductase 1
lipase 1
beta-glucuronidase 1
pyruvate dehydrogenase 1
lysyl oxidase 1
methionine synthase 1
RNase 1
hyaluronidase 1
UDP-N-acetylglucosamine 4-epimerase 1
diamine oxidase 1
glyceraldehyde-3-phosphate dehydrogenase 1
chondroitinase 1
pyruvate dehydrogenase 1
cellulase 1
chondroitinase 1
peroxidase 1
delta-aminolevulinic acid dehydratase 1
RNase 1
glycerol 3-phosphate dehydrogenase 1
diaphorase 1
aconitase 1
NOS 1
ALA synthase 1
cholinesterase 1
thioredoxin reductase 1
glyceraldehyde-3-phosphate dehydrogenase 1
protein kinase 1
ribonuclease 1
glyceraldehyde-3-phosphate dehydrogenase 1
IKK 1
dopamine beta-hydroxylase 1
UDP-glucuronosyltransferase 1
methionine synthase 1
3-hydroxy-3-methylglutaryl coenzyme A reductase 1
ribonuclease 1
aldehyde reductase 1
4-hydroxyphenylpyruvate dioxygenase 1
lysyl hydroxylase 1
cholesterol acyltransferase 1
prolidase 1
adenylate cyclase 1
fructokinase 1
myosin light chain kinase 1
6-phosphogluconate dehydrogenase 1
ACS 1
glyceraldehyde-3-phosphate dehydrogenase 1
pyruvate dehydrogenase 1
glyceraldehyde-3-phosphate dehydrogenase 1
aldehyde reductase 1
mitogen-activated protein kinase 1
ferrochelatase 1
beta-glucosidase 1
succinic dehydrogenase 1
alpha-galactosidase 1
thrombin 1
glucose-6-phosphate dehydrogenase 1
DNA methyltransferase 1
tryptophan hydroxylase 1
cystathionine gamma-synthase 1
asparaginase 1
cytochrome oxidase 1
aldehyde reductase 1
Compound
Ascorbic acid 122
Clin 48
water 39
Dec 37
iron 37
proline 28
glucose 24
DNA 20
oxygen 13
calcium 13
vitamin D 11
zinc 10
sulfate 9
sodium 9
lysine 8
copper 7
acetate 7
Collagen 7
phosphate 6
galactose 6
GSH 6
2-oxoglutarate 6
GSH 6
aniline 5
His 5
oxalate 5
nitric oxide 5
NADPH 5
NADPH 5
retinol 5
methionine 5
nitrogen 5
Dial 5
tryptophan 4
ACTH 4
tyrosine 4
ethanol 4
salt 4
Vitamin A 3
tryptophan 3
oxalic acid 3
oxalic acid 3
oxalic acid 3
oxalic acid 3
oxalic acid 3
DHA 3
oxalic acid 3
oxalic acid 3
TEM 3
oxalic acid 3
oxalic acid 3
oxalic acid 3
oxalic acid 3
L-carnitine 3
nitrate 3
Thiamine 3
tryptophan 3
Cholesterol 3
PGA 3
homocysteine 3
oxalic acid 3
creatinine 3
Dehydroascorbic acid 3
tryptophan 3
selenium 3
oxalic acid 3
oxalic acid 3
SDS 3
TET 3
oxalic acid 3
oxalic acid 3
phosphorus 3
Estrogen 3
trimethyllysine 3
TET 3
oxalic acid 3
alanine 3
hexose 2
CoA 2
NADH 2
NADP 2
FAD 2
Cardiol 2
NAD 2
ATP 2
NAD 2
Estrogen 2
urea 2
hydrogen 2
delta-aminolevulinic acid 2
TCA 2
L-Gulonolactone 2
GSSG 2
DHA 2
UGA 2
hexose 2
potassium 2
cysteine 2
DHA 2
threonate 2
hydroxyindoleacetic acid 2
hexose 2
Antipyrine 2
Fenfluramine 2
hexose 2
prostaglandin E1 1
vanadium 1
2,4,6-trimethylpyridine 1
Prostaglandin 1
butyric acid 1
GDP 1
HCO 1
A 1 1
carbonate 1
Mg2+ 1
alcohol dehydrogenase 1
Diethylpropion 1
8-OHdG 1
hexuronic acid 1
butyric acid 1
hexuronic acid 1
palmitic acid 1
mercury 1
Vinblastine 1
chlorobenzene 1
MPTP 1
acridine 1
Indomethacin 1
Palmitic acid 1
Metformin 1
serine 1
hydrazine 1
TDP 1
pentose 1
Sucrose 1
hydroxide 1
Hydroxyproline 1
ACS 1
Metyrapone 1
Prostaglandin 1
Neuronal 1
5H-pyrido[4,3-b]indole 1
Vitamin E 1
arginine 1
SCN 1
pentose 1
UDP 1
aspartic acid 1
Vitamin D 1
Pyridinoline 1
threonine 1
Metyrapone 1
Thyroxine 1
Collagenase 1
Biotin 1
aspartic acid 1
glutamate 1
Luminal 1
Clozapine 1
Lactate 1
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 1
xylose 1
EDTA 1
Gulonate 1
TNF 1
MMD 1
AMP 1
Amlodipine 1
FFA 1
noradrenaline 1
Adrenal 1
GAL 1
prostacyclin 1
DLT 1
Histamine 1
THF 1
Methazolamide 1
Thiobarbituric acid 1
Phe 1
Betamethasone 1
glycerol 1
L-leucine 1
uridine 1
Insulin 1
D-glucuronic acid 1
hyaluronic acid 1
EDTA 1
Asp 1
hexuronic acid 1
ACh 1
fluorine 1
aspartic acid 1
nicotinamide 1
ACS 1
aspartic acid 1
hexuronic acid 1
superoxide radical 1
ABA 1
silicon 1
pentose 1
acetone 1
DMF 1
5-HT 1
ASC 1
Tetrahydrobiopterin 1
retinoic acid 1
CIT 1
Hemoglobin 1
Trp-P-2 1
thiourea 1
iodine 1
D-glucuronate 1
caffeine 1
TPP 1
Retinal 1
25-hydroxycholecalciferol 1
Benzanthrone 1
Carnitine 1
2,4,6-trimethylpyridine 1
Thyroid 1
barium 1
butyric acid 1
H2O2 1
Gulonate 1
pentose 1
25-dihydroxycholecalciferol 1
Metformin 1
Triton 1
Colchicine 1
MDA 1
Neomycin 1
leucine 1
DEAE 1