Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003969 (vitamin C deficiency)
 625 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Scurvy is a disease that can mimic other more serious disorders such as deep vein thrombosis, vasculitis, and systemic bleeding disorders. Because the clinical features of scurvy are no longer well appreciated, scorbutic patients are often extensively evaluated for other disorders. Familiarity with the risk factors for and clinical manifestation of scurvy can facilitate earlier diagnosis. We report three patients who highlight the epidemiology, clinical features, and differential diagnosis of scurvy.
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PMID:Adult scurvy. 396 18

Scurvy can mimic disorders such as vasculitis, systemic bleeding disorders, and deep vein thrombosis. For this reason scorbutic patients are often evaluated for other disorders thus delaying the correct diagnosis. Health care providers may be able to prevent cases of scurvy with knowledge of the clinical features of scurvy and higher levels of suspicion of high risk groups. These groups include older people living alone, young children eating exclusively cow's milk formula, food faddists, and those consuming inadequate diets for reasons such as mental illness or peptic ulcer.
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PMID:Scurvy by any other name: a case report. 811 66

Scurvy, caused by vitamin C deficiency, is very rare nowadays in the developed world. Scattered cases are found in people with unusual eating habits, alcoholism, intestinal malabsorption, mental disorders, or elderly living alone. Because of its rarity, clinical presentations of scurvy, especially anemia and bleeding, are no longer well appreciated, and consequently extensive evaluation is commonly launched to pursue scurvy mimics, such as deep vein thrombosis, vasculitis, systemic coagulation disorders, and myelodysplasia. Herein, we describe the clinical manifestations and lab findings in a scurvy patient to raise awareness of this uncommon disease.
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PMID:Behind the Skin: A Rare Case of Scurvy-Associated Megaloblastic Anemia. 3120 33