Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0003873 (rheumatoid arthritis)
53,068 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein cytokine 3552 Sep 3058 collagen 2619 TNF 2577 rheumatoid factor 2386 tumor necrosis factor 2056 IL-6 1832 ankylosing spondylitis 1627 Mol 1369 C-reactive protein 1228 HLA 1084 CD4 1013 TNF-alpha 998 IL-17 850 IL-1 819 type II collagen 700 IgA 689 IL-10 646 She 636 lymphoid 617 interleukin-6 610 ESR 570 CRP 521 lipopolysaccharide 519 IL-8 502 IFN 444 RANKL 443 IL-4 440 insulin 428 chemokine 428 HLA-DR 417 CCP 415 IL-2 404 interferon 403 DR4 402 tumor necrosis factor alpha 380 IFN-gamma 364 p38 354 Cytokine 350 CD20 343 HLA-DR4 328 DBA 322 CD8 320 MRI 309 HLA-DRB1 309 Tumor necrosis factor 307 glycoprotein 303 LPS 301 COX-2 301 major histocompatibility complex 292 gut 287 autoantigen 286 ACR 277 matrix metalloproteinase 275 MHC 257 interferon-gamma 254 collagenase 242 cyclooxygenase 241 Mal 233 albumin 231 CD28 230 MAPK 227 vascular endothelial growth factor 224 fibrinogen 222 IL-1 beta 216 Janus kinase 214 proteoglycan 213 alkaline phosphatase 212 p65 212 MMP-3 210 serum albumin 205 IL-23 205 CD25 204 cyclooxygenase-2 203 T cell receptor 202 hemoglobin 198 TCR 187 myeloperoxidase 185 fibronectin 185 TNF receptor 184 more...

Disease rheumatoid arthritis 53068 arthritis 9593 systemic lupus erythematosus 5290 osteoarthritis 4387 autoimmune disease 2618 cancer 2486 multiple sclerosis 1753 synovitis 1733 ankylosing spondylitis 1711 psoriasis 1703 diabetes 1637 psoriatic arthritis 1441 osteoporosis 1302 vasculitis 1264 lupus 1256 inflammatory bowel disease 1136 Crohn's disease 1101 arthropathy 1093 PSS 1073 atherosclerosis 1049 lupus 944 tumor 923 asthma 871 polyarthritis 715 tuberculosis 714 rheumatism 652 cardiovascular disease 648 depression 605 hypertension 589 scleroderma 547 gout 529 arthrodesis 526 type 1 diabetes 523 lymphoma 476 dermatomyositis 463 ulcerative colitis 462 obesity 440 juvenile rheumatoid arthritis 433 amyloidosis 415 PCC 415 polymyositis 410 pneumonia 405 sepsis 399 anemia 390 fibromyalgia 385 sepsis 380 Epstein 375 Best 360 infectious diseases 352 connective tissue disease 350 periodontitis 344 Alzheimer's disease 329 sarcoidosis 327 DBA 323 interstitial lung disease 318 chronic disease 316 mixed connective tissue disease 315 SLE 311 leukemia 306 proteinuria 298 HIV 297 glomerulonephritis 296 Sjogren's syndrome 294 stroke 293 Mycobacterium 292 multiple myeloma 288 systemic disease 284 hepatitis 280 renal disease 277 rash 276 interstitial pneumonia 273 plaque 269 chronic pain 263 immunodeficiency 251 inflammatory joint disease 250 polymyalgia rheumatica 245 septic arthritis 241 myasthenia gravis 237 myocardial infarction 235 thrombocytopenia 234 more...

Symptom pain 3888 arthralgia 493 fatigue 434 swollen joints 334 diarrhea 242 dyspnea 221 weakness 212 headache 207 erythema 162 cough 160 low back pain 139 nausea 134 back pain 133 splenomegaly 129 abdominal pain 111 discomfort 98 discomfort 93 anesthesia 90 neck pain 87 collapse 85 cachexia 84 analgesia 82 vomiting 81 myalgia 70 dry eye 65 acute pain 61 seizures 57 respiratory distress 54 joint stiffness 48 Ill 47 hip pain 46 overweight 46 anorexia 45 knee pain 44 thinning 40 shortness of breath 39 chest pain 39 exertional dyspnea 38 numbness 37 tinnitus 36 angina 36 dizziness 36 shoulder pain 35 constipation 33 paresthesia 32 polymyalgia 26 nausea and vomiting 25 hoarseness 25 sleepiness 25 hepatosplenomegaly 25 hemoptysis 24 cancer pain 23 wrist pain 22 sciatica 22 insomnia 22 dental pain 21 livedo 21 starvation 21 hepatomegaly 21 chills 21 hemiplegia 21 exhaustion 20 fever of unknown origin 20 productive cough 20 neuralgia 19 paresis 19 epigastric pain 18 dysarthria 18 stridor 18 asthenia 18 sore throat 17 metatarsalgia 17 spasm 16 vertigo 15 functional recovery 15 syncope 15 heartburn 15 ataxia 15 alexithymia 14 chronic back pain 14 more...

Drug Dermatol 494 IL-2 406 IFN-gamma 349 Infliximab 259 Infliximab 259 Rituximab 208 CSF 201 Tocilizumab 167 Adalimumab 146 p75 130 Abatacept 122 Auranofin 119 CIA 113 lysine 100 IL-1ra 85 Cardiovasc 80 CTX 75 ROS 74 Indomethacin 68 vitamin E 64 ROC 62 Anakinra 54 Monit 54 Asthma 53 Sulphasalazine 46 ascorbate 43 Prednisolone 43 CTX 42 CTX 42 Gel 35 Dial 34 IL-11 32 Prednisone 32 Tacrolimus 31 MAP 31 IFN-beta 30 Golimumab 29 Nephron 26 PTH 25 BLyS 25 Etodolac 25 EPA 25 Bucillamine 25 Gold sodium thiomalate 25 Denosumab 24 G-CSF 24 Misoprostol 24 Diclofenac sodium 23 caffeine 23 Nabumetone 21 Albumin 21 ABC 20 Certolizumab pegol 19 Nephron 19 Histamine 18 Fragment 18 Tenidap 18 Voltaren 17 lactose 17 FLP 17 ENT 16 Tenoxicam 16 Profenid 15 Estrogens 15 Leaf 15 Mizoribine 15 Iguratimod 15 Hypaque 14 Methylprednisolone 14 Hypaque 14 Retinoic acid 14 Asn 14 CAM 13 Aceclofenac 13 Fluorescein 12 Imatinib 12 Tiaprofenic acid 12 Arava 12 DNase I 12 Bifidobacterium 12 more...

Enzyme mitogen-activated protein kinase 632 collagenase 424 focal adhesion kinase 313 peroxidase 302 ERK 302 MMP-3 266 alkaline phosphatase 212 superoxide dismutase 180 protein kinase 152 catalase 137 luciferase 135 trypsin 117 elastase 116 caspase-3 113 phospholipase A2 109 peptidylarginine deiminase 106 proteasome 97 cathepsin K 92 protein kinase C 89 IKK 85 glutathione peroxidase 82 lysozyme 73 alanine aminotransferase 73 reverse transcriptase 69 aspartate aminotransferase 66 ceruloplasmin 66 thrombin 66 acid phosphatase 64 MEK 63 lactate dehydrogenase 63 caspase-1 61 NADPH oxidase 61 MMP 61 neutrophil elastase 59 ACS 57 NADPH oxidase 57 MIP 54 NO synthase 54 urokinase-type plasminogen activator 50 phosphoglucose isomerase 50 calcineurin 50 plasmin 49 arginine deiminase 49 dihydroorotate dehydrogenase 47 dihydroorotate dehydrogenase 47 RNase 42 matrix metalloproteinase 9 42 beta-glucuronidase 42 RNase 41 lipoxygenase 39 ACE 39 ATPase 39 P-glycoprotein 38 pepsin 38 cathepsin G 37 cathepsin B 37 APC 37 hyaluronidase 36 phosphodiesterase 35 kallikrein 35 adenosine deaminase 35 phosphatidylinositol 3-kinase 34 adenosine deaminase 34 hyaluronidase 34 PARP 33 RNA polymerase 32 gamma-glutamyl transpeptidase 31 DNase 30 glutathione S-transferase 30 creatine kinase 30 dihydrofolate reductase 30 caspase-9 30 phospholipase C 30 interstitial collagenase 30 CD10 29 AMP-activated protein kinase 28 papain 27 thioredoxin reductase 26 phosphoinositide 3-kinase 26 renin 26 more...

Compound Clin 7593 Dec 3645 TNF 2577 DNA 1606 calcium 864 oxygen 747 Methotrexate 709 sodium 575 CCP 415 nitric oxide 357 DBA 322 DBA 322 DBA 322 water 313 arginine 298 glucose 295 iron 287 acetate 281 creatinine 274 phosphate 267 vitamin D 258 Etanercept 234 tyrosine 234 Hearts 223 Collagen 219 HAQ 216 PEG 203 sulfate 198 cysteine 185 His 178 zinc 178 MTX 172 ATP 167 Leflunomide 166 PGE2 166 BMC 159 galactose 159 hydrogen 159 leucine 154 lysine 146 serine 130 copper 130 salt 129 THP 125 THP 125 hyaluronic acid 125 nitrogen 123 PGE 116 Phe 112 cAMP 107 alanine 104 Cardiol 103 DPA 100 DPA 100 ANA 100 DPA 100 pyrimidine 100 DPA 100 DPA 100 ANA 100 pyrimidine 99 MTT 98 ASA 97 ethanol 94 GSH 93 GSH 93 tryptophan 92 ANCA 91 SDS 89 PEG 89 tryptophan 87 tryptophan 86 tryptophan 86 potassium 84 urea 83 CTX 75 EDTA 73 EDTA 73 Sulfasalazine 72 Celecoxib 70 more...

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