Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0003873 (rheumatoid arthritis)
53,068 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein cytokine 3552 Sep 3058 collagen 2619 TNF 2577 rheumatoid factor 2386 tumor necrosis factor 2056 IL-6 1832 ankylosing spondylitis 1627 Mol 1369 C-reactive protein 1228 HLA 1084 CD4 1013 TNF-alpha 998 IL-17 850 IL-1 819 type II collagen 700 IgA 689 IL-10 646 She 636 lymphoid 617 interleukin-6 610 ESR 570 CRP 521 lipopolysaccharide 519 IL-8 502 IFN 444 RANKL 443 IL-4 440 insulin 428 chemokine 428 HLA-DR 417 CCP 415 IL-2 404 interferon 403 DR4 402 tumor necrosis factor alpha 380 IFN-gamma 364 p38 354 Cytokine 350 CD20 343 more...

Disease rheumatoid arthritis 53068 arthritis 9593 systemic lupus erythematosus 5290 osteoarthritis 4387 autoimmune disease 2618 cancer 2486 multiple sclerosis 1753 synovitis 1733 ankylosing spondylitis 1711 psoriasis 1703 diabetes 1637 psoriatic arthritis 1441 osteoporosis 1302 vasculitis 1264 lupus 1256 inflammatory bowel disease 1136 Crohn's disease 1101 arthropathy 1093 PSS 1073 atherosclerosis 1049 lupus 944 tumor 923 asthma 871 polyarthritis 715 tuberculosis 714 rheumatism 652 cardiovascular disease 648 depression 605 hypertension 589 scleroderma 547 gout 529 arthrodesis 526 type 1 diabetes 523 lymphoma 476 dermatomyositis 463 ulcerative colitis 462 obesity 440 juvenile rheumatoid arthritis 433 amyloidosis 415 PCC 415 more...

Symptom pain 3888 arthralgia 493 fatigue 434 swollen joints 334 diarrhea 242 dyspnea 221 weakness 212 headache 207 erythema 162 cough 160 low back pain 139 nausea 134 back pain 133 splenomegaly 129 abdominal pain 111 discomfort 98 discomfort 93 anesthesia 90 neck pain 87 collapse 85 cachexia 84 analgesia 82 vomiting 81 myalgia 70 dry eye 65 acute pain 61 seizures 57 respiratory distress 54 joint stiffness 48 Ill 47 hip pain 46 overweight 46 anorexia 45 knee pain 44 thinning 40 shortness of breath 39 chest pain 39 exertional dyspnea 38 numbness 37 tinnitus 36 more...

Drug Dermatol 494 IL-2 406 IFN-gamma 349 Infliximab 259 Infliximab 259 Rituximab 208 CSF 201 Tocilizumab 167 Adalimumab 146 p75 130 Abatacept 122 Auranofin 119 CIA 113 lysine 100 IL-1ra 85 Cardiovasc 80 CTX 75 ROS 74 Indomethacin 68 vitamin E 64 ROC 62 Monit 54 Anakinra 54 Asthma 53 Sulphasalazine 46 Prednisolone 43 ascorbate 43 CTX 42 CTX 42 Gel 35 Dial 34 Prednisone 32 IL-11 32 MAP 31 Tacrolimus 31 IFN-beta 30 Golimumab 29 Nephron 26 EPA 25 Gold sodium thiomalate 25 more...

Enzyme mitogen-activated protein kinase 632 collagenase 424 focal adhesion kinase 313 ERK 302 peroxidase 302 MMP-3 266 alkaline phosphatase 212 superoxide dismutase 180 protein kinase 152 catalase 137 luciferase 135 trypsin 117 elastase 116 caspase-3 113 phospholipase A2 109 peptidylarginine deiminase 106 proteasome 97 cathepsin K 92 protein kinase C 89 IKK 85 glutathione peroxidase 82 alanine aminotransferase 73 lysozyme 73 reverse transcriptase 69 thrombin 66 aspartate aminotransferase 66 ceruloplasmin 66 acid phosphatase 64 lactate dehydrogenase 63 MEK 63 MMP 61 caspase-1 61 NADPH oxidase 61 neutrophil elastase 59 ACS 57 NADPH oxidase 57 NO synthase 54 MIP 54 urokinase-type plasminogen activator 50 phosphoglucose isomerase 50 more...

Compound Clin 7593 Dec 3645 TNF 2577 DNA 1606 calcium 864 oxygen 747 Methotrexate 709 sodium 575 CCP 415 nitric oxide 357 DBA 322 DBA 322 DBA 322 water 313 arginine 298 glucose 295 iron 287 acetate 281 creatinine 274 phosphate 267 vitamin D 258 tyrosine 234 Etanercept 234 Hearts 223 Collagen 219 HAQ 216 PEG 203 sulfate 198 cysteine 185 zinc 178 His 178 MTX 172 ATP 167 PGE2 166 Leflunomide 166 BMC 159 galactose 159 hydrogen 159 leucine 154 lysine 146 more...

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