Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003873 (rheumatoid arthritis)
 53,068 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
cytokine 3552
Sep 3058
collagen 2619
TNF 2577
rheumatoid factor 2386
tumor necrosis factor 2056
IL-6 1832
ankylosing spondylitis 1627
Mol 1369
C-reactive protein 1228
HLA 1084
CD4 1013
TNF-alpha 998
IL-17 850
IL-1 819
type II collagen 700
IgA 689
IL-10 646
She 636
lymphoid 617
more...
Disease
rheumatoid arthritis 53068
arthritis 9593
systemic lupus erythematosus 5290
osteoarthritis 4387
autoimmune disease 2618
cancer 2486
multiple sclerosis 1753
synovitis 1733
ankylosing spondylitis 1711
psoriasis 1703
diabetes 1637
psoriatic arthritis 1441
osteoporosis 1302
vasculitis 1264
lupus 1256
inflammatory bowel disease 1136
Crohn's disease 1101
arthropathy 1093
PSS 1073
atherosclerosis 1049
more...
Symptom
pain 3888
arthralgia 493
fatigue 434
swollen joints 334
diarrhea 242
dyspnea 221
weakness 212
headache 207
erythema 162
cough 160
low back pain 139
nausea 134
back pain 133
splenomegaly 129
abdominal pain 111
discomfort 98
discomfort 93
anesthesia 90
neck pain 87
collapse 85
more...
Drug
Dermatol 494
IL-2 406
IFN-gamma 349
Infliximab 259
Infliximab 259
Rituximab 208
CSF 201
Tocilizumab 167
Adalimumab 146
p75 130
Abatacept 122
Auranofin 119
CIA 113
lysine 100
IL-1ra 85
Cardiovasc 80
CTX 75
ROS 74
Indomethacin 68
vitamin E 64
more...
Enzyme
mitogen-activated protein kinase 632
collagenase 424
focal adhesion kinase 313
peroxidase 302
ERK 302
MMP-3 266
alkaline phosphatase 212
superoxide dismutase 180
protein kinase 152
catalase 137
luciferase 135
trypsin 117
elastase 116
caspase-3 113
phospholipase A2 109
peptidylarginine deiminase 106
proteasome 97
cathepsin K 92
protein kinase C 89
IKK 85
more...
Compound
Clin 7593
Dec 3645
TNF 2577
DNA 1606
calcium 864
oxygen 747
Methotrexate 709
sodium 575
CCP 415
nitric oxide 357
DBA 322
DBA 322
DBA 322
water 313
arginine 298
glucose 295
iron 287
acetate 281
creatinine 274
phosphate 267
more...