Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0003873 (rheumatoid arthritis)
 53,068 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A T gamma-lymphoproliferative syndrome is described in a 69-year-old woman with seropositive rheumatoid arthritis. The phenotype of this non-clonally increased large granular lymphocyte (LGL) population is unusual: LGL are CD56- Fc gamma RIII+(CD16+) and 30% coexpress gamma/delta-T-cell receptor.
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PMID:[Syndrome of T gamma lymphoproliferation of Fc gamma RIII- positive lymphocytes in rheumatoid arthritis]. 834 74

T gamma lymphocytosis is an infrequent entity, generally benign and distinct of the spectrum of the T cell chronic lymphoproliferative syndromes, that it not need or need short therapy, with a prolongated survival. T gamma lymphocytosis is expressive in the most of the occasions of a monoclonal lymphocytic proliferation and it is frequently associated to Rheumatoid Arthritis. We present the case of a patient with T gamma lymphocytosis, developed after several years of evolution of Rheumatoid Arthritis and that it was coincident with two solid neoplasms, an infiltrate carcinoma of the larynx and recurrent urothelial carcinoma, without previous chemotherapy. The death in this patients, is generally due a progressive lymphoproliferation and sepsis relationed with the neutropenia.
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PMID:[T-gamma lymphocytosis associated with two solid neoplasms in a patient with rheumatoid arthritis]. 965 14


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