Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0003864 (
arthritis
)
69,039
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
3943
collagen
3707
cytokine
2307
TNF
1541
IL-6
1331
type II collagen
1255
tumor necrosis factor
1130
ankylosing spondylitis
1091
rheumatoid factor
926
Mol
879
HLA
738
IL-1
707
HLA-B27
693
CD4
688
IL-17
681
DBA
664
IL-10
639
TNF-alpha
590
lipopolysaccharide
581
C-reactive protein
538
proteoglycan
494
B27
453
She
430
IFN
412
IL-4
393
IFN-gamma
392
interferon
387
lymphoid
382
interleukin-6
372
COX-2
339
MRI
339
LPS
335
IgA
334
gut
295
matrix metalloproteinase
293
chemokine
279
cyclooxygenase
276
tumor necrosis factor alpha
269
p38
267
IL-2
260
more...
Disease
arthritis
69039
rheumatoid arthritis
9593
osteoarthritis
3365
systemic lupus erythematosus
2430
cancer
1814
diabetes
1380
synovitis
1344
psoriatic arthritis
1270
autoimmune disease
1255
polyarthritis
1227
ankylosing spondylitis
1217
arthropathy
1207
psoriasis
1133
gout
1107
vasculitis
987
rash
948
lupus
872
arthrodesis
801
hypertension
773
septic arthritis
768
lupus
707
HLA-B27
693
juvenile rheumatoid arthritis
684
DBA
664
inflammatory bowel disease
662
osteoporosis
653
uveitis
613
tumor
568
depression
566
tuberculosis
554
obesity
552
encephalitis
538
asthma
530
Lyme disease
524
rheumatism
516
atherosclerosis
508
sepsis
507
osteomyelitis
494
pneumonia
466
Reiter's syndrome
456
more...
Symptom
pain
4530
arthralgia
1201
erythema
501
diarrhea
392
fatigue
343
abdominal pain
330
back pain
313
myalgia
286
headache
284
weakness
279
knee pain
179
collapse
171
low back pain
168
splenomegaly
163
swollen joints
130
anesthesia
124
analgesia
120
discomfort
118
discomfort
110
Ill
108
hepatosplenomegaly
102
overweight
97
dyspnea
88
seizures
88
hip pain
88
nausea
87
sore throat
86
distraction
84
vomiting
84
acute pain
69
chorea
68
shoulder pain
66
anorexia
64
cough
61
chest pain
61
hepatomegaly
60
cachexia
60
clubbing
55
angina
53
wrist pain
50
more...
Drug
Dermatol
467
IFN-gamma
383
IL-2
261
CIA
186
CSF
137
lysine
86
Indomethacin
80
CTX
68
Infliximab
65
Infliximab
65
ROS
63
IL-1ra
63
Tocilizumab
59
Adalimumab
57
ampicillin
56
p75
56
ascorbate
45
Cardiovasc
45
Prednisolone
39
vitamin E
36
Anakinra
36
Rituximab
35
CTX
29
Sulphasalazine
29
CTX
29
Asthma
27
MAP
26
Abatacept
26
Monit
24
Auranofin
21
THA
21
Vioxx
19
Histamine
17
Leaf
17
Prednisone
17
Alliance
16
Etodolac
16
Gel
15
Asn
15
Febuxostat
15
more...
Enzyme
mitogen-activated protein kinase
430
collagenase
355
peroxidase
230
ERK
206
MMP-3
197
superoxide dismutase
197
focal adhesion kinase
174
alkaline phosphatase
146
catalase
129
protein kinase
96
luciferase
89
xanthine oxidase
89
trypsin
87
reverse transcriptase
77
MMP
76
glutathione peroxidase
76
phospholipase A2
71
alanine aminotransferase
69
elastase
69
NO synthase
67
caspase-1
66
lysozyme
66
phosphoglucose isomerase
61
caspase-3
60
protein kinase C
55
proteasome
55
lipoxygenase
55
acid phosphatase
55
IKK
53
lactate dehydrogenase
53
NADPH oxidase
53
NADPH oxidase
52
cathepsin K
51
ACS
51
aspartate aminotransferase
50
hyaluronidase
50
thrombin
48
MIP
48
APC
46
hyaluronidase
43
more...
Compound
Clin
4873
Dec
4820
TNF
1541
DNA
1410
DBA
664
DBA
664
DBA
664
calcium
655
oxygen
532
sodium
425
nitric oxide
422
water
395
Collagen
314
sulfate
264
phosphate
255
Methotrexate
220
glucose
212
iron
202
hyaluronic acid
199
zinc
194
acetate
190
acetic acid
172
His
171
PGE2
169
arginine
168
creatinine
157
tyrosine
146
PGE
143
cysteine
126
ATP
125
ethanol
125
CCP
122
ANA
118
ANA
118
lysine
118
hydrogen
112
vitamin D
112
serine
111
PEG
106
leucine
104
more...