Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003864 (arthritis)
69,039 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 3943
collagen 3707
cytokine 2307
TNF 1541
IL-6 1331
type II collagen 1255
tumor necrosis factor 1130
ankylosing spondylitis 1091
rheumatoid factor 926
Mol 879
HLA 738
IL-1 707
HLA-B27 693
CD4 688
IL-17 681
DBA 664
IL-10 639
TNF-alpha 590
lipopolysaccharide 581
C-reactive protein 538
proteoglycan 494
B27 453
She 430
IFN 412
IL-4 393
IFN-gamma 392
interferon 387
lymphoid 382
interleukin-6 372
COX-2 339
MRI 339
LPS 335
IgA 334
gut 295
matrix metalloproteinase 293
chemokine 279
cyclooxygenase 276
tumor necrosis factor alpha 269
p38 267
IL-2 260
more...
Disease
arthritis 69039
rheumatoid arthritis 9593
osteoarthritis 3365
systemic lupus erythematosus 2430
cancer 1814
diabetes 1380
synovitis 1344
psoriatic arthritis 1270
autoimmune disease 1255
polyarthritis 1227
ankylosing spondylitis 1217
arthropathy 1207
psoriasis 1133
gout 1107
vasculitis 987
rash 948
lupus 872
arthrodesis 801
hypertension 773
septic arthritis 768
lupus 707
HLA-B27 693
juvenile rheumatoid arthritis 684
DBA 664
inflammatory bowel disease 662
osteoporosis 653
uveitis 613
tumor 568
depression 566
tuberculosis 554
obesity 552
encephalitis 538
asthma 530
Lyme disease 524
rheumatism 516
atherosclerosis 508
sepsis 507
osteomyelitis 494
pneumonia 466
Reiter's syndrome 456
more...
Symptom
pain 4530
arthralgia 1201
erythema 501
diarrhea 392
fatigue 343
abdominal pain 330
back pain 313
myalgia 286
headache 284
weakness 279
knee pain 179
collapse 171
low back pain 168
splenomegaly 163
swollen joints 130
anesthesia 124
analgesia 120
discomfort 118
discomfort 110
Ill 108
hepatosplenomegaly 102
overweight 97
dyspnea 88
seizures 88
hip pain 88
nausea 87
sore throat 86
distraction 84
vomiting 84
acute pain 69
chorea 68
shoulder pain 66
anorexia 64
cough 61
chest pain 61
hepatomegaly 60
cachexia 60
clubbing 55
angina 53
wrist pain 50
more...
Drug
Dermatol 467
IFN-gamma 383
IL-2 261
CIA 186
CSF 137
lysine 86
Indomethacin 80
CTX 68
Infliximab 65
Infliximab 65
ROS 63
IL-1ra 63
Tocilizumab 59
Adalimumab 57
ampicillin 56
p75 56
ascorbate 45
Cardiovasc 45
Prednisolone 39
vitamin E 36
Anakinra 36
Rituximab 35
CTX 29
Sulphasalazine 29
CTX 29
Asthma 27
MAP 26
Abatacept 26
Monit 24
Auranofin 21
THA 21
Vioxx 19
Histamine 17
Leaf 17
Prednisone 17
Alliance 16
Etodolac 16
Gel 15
Asn 15
Febuxostat 15
more...
Enzyme
mitogen-activated protein kinase 430
collagenase 355
peroxidase 230
ERK 206
MMP-3 197
superoxide dismutase 197
focal adhesion kinase 174
alkaline phosphatase 146
catalase 129
protein kinase 96
luciferase 89
xanthine oxidase 89
trypsin 87
reverse transcriptase 77
MMP 76
glutathione peroxidase 76
phospholipase A2 71
alanine aminotransferase 69
elastase 69
NO synthase 67
caspase-1 66
lysozyme 66
phosphoglucose isomerase 61
caspase-3 60
protein kinase C 55
proteasome 55
lipoxygenase 55
acid phosphatase 55
IKK 53
lactate dehydrogenase 53
NADPH oxidase 53
NADPH oxidase 52
cathepsin K 51
ACS 51
aspartate aminotransferase 50
hyaluronidase 50
thrombin 48
MIP 48
APC 46
hyaluronidase 43
more...
Compound
Clin 4873
Dec 4820
TNF 1541
DNA 1410
DBA 664
DBA 664
DBA 664
calcium 655
oxygen 532
sodium 425
nitric oxide 422
water 395
Collagen 314
sulfate 264
phosphate 255
Methotrexate 220
glucose 212
iron 202
hyaluronic acid 199
zinc 194
acetate 190
acetic acid 172
His 171
PGE2 169
arginine 168
creatinine 157
tyrosine 146
PGE 143
cysteine 126
ATP 125
ethanol 125
CCP 122
ANA 118
ANA 118
lysine 118
hydrogen 112
vitamin D 112
serine 111
PEG 106
leucine 104
more...