Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003635 (apraxia)
 2,817 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
FAM149B1 13.5
C4orf21 13.5
senataxin 12.7
aprataxin 12.6
ALS4 12.5
ANKRD12 12.5
APTX 12.4
SETX 12.0
ZNF280D 11.9
MKS6 11.5
PNKP 11.4
ATLD 11.1
NAGPA 11.1
KPTN 10.9
PAPOLG 10.9
PIK3R5 10.7
EFCAB4B 10.7
FOXP2 10.6
PARP11 10.5
TSPAN9 10.5
IOSCA 10.5
nephrocystin-4 10.3
SCAR1 10.3
forkhead box P2 10.2
glutaryl CoA dehydrogenase 10.1
SANDO 10.1
cerebellin 1 precursor 10.0
TMEM216 10.0
GLP2R 10.0
CDH18 10.0
FOXP2 protein 10.0
POLG protein 9.9
Caytaxin 9.9
GATAD2B 9.8
RIMS1 9.8
NPHP1 9.7
NPHP4 9.6
B3GALNT2 9.6
AOA 9.6
nephrocystin 9.5
SLC30A9 9.5
CC2D2A 9.4
GNPTG 9.4
NGL-1 9.4
ZFHX4 9.3
MYO10 9.3
COQ4 9.2
STX6 9.2
ADCK4 9.2
Abelson helper integration site 1 9.0
PDE6D 9.0
COQ6 9.0
INPP5E 9.0
LBX1 8.9
thioesterase superfamily member 2 8.9
SMCR8 8.9
Disrupted in schizophrenia 1 8.9
PDSS2 8.8
TTRAP 8.8
NEK8 8.8
Synaptojanin 1 8.7
contactin 4 8.7
forkhead box P1 8.7
XRCC1 protein 8.6
SPTBN2 8.6
SACS 8.6
2E4 8.6
AHI1 8.6
TNRC6B 8.6
ADCK3 8.6
IMMP2L 8.6
GRID2 8.5
X-ray repair cross-complementing protein 1 8.5
ELP4 8.5
meiotic recombination 11 8.5
CNTNAP2 8.5
COQ9 8.5
GNPTAB 8.4
ATP8A2 8.4
ZNF423 8.4
POMGnT1 8.4
CNTN4 8.3
galactose-1-phosphate uridyltransferase 8.3
DAG1 8.3
DNA ligase III 8.2
ERC1 8.2
nibrin 8.2
POMT2 8.2
PPP1R3 8.1
MAP2 protein 8.1
TUSC3 8.1
NPHP2 8.1
SCA12 8.1
SLC6A8 8.1
CMIP 8.0
MKL2 8.0
POMT1 8.0
ATM protein 8.0
NPHP3 8.0
tyrosyl-DNA phosphodiesterase 1 8.0
ARL13B 7.9
NFBD1 7.9
MOBP 7.9
LAMA1 7.9
KIAA0319 7.9
Succinic semialdehyde dehydrogenase 7.8
HSL1 7.8
DARS2 7.8
NSA 7.7
FOXP1 7.7
AFG3L2 7.6
GRN 7.6
MKS1 7.6
ALX4 7.6
ADSL 7.6
galactose-1-phosphate uridyl transferase 7.5
p101 7.5
WDR45 7.5
CHD3 7.4
OFD 7.4
Aristaless-related homeobox 7.4
DISC1 protein 7.4
BPP 7.4
MPV17 7.4
KAT6A 7.4
SPOCK1 7.4
SCA8 7.4
CACT 7.4
Hallervorden-Spatz syndrome 7.3
RD3 7.3
SPCA2 7.3
TUTase 7.3
TCF12 7.3
POLR2A 7.3
boule 7.3
Rett syndrome 7.3
RAI1 7.3
DYX1C1 7.3
creatine transporter 7.3
SCA17 7.3
DPP6 7.2
COQ2 7.2
fukutin 7.2
SLC22A3 7.2
LARGE 7.2
GRIN2A 7.2
TMEM106B 7.1
PSP 7.1
THAP1 7.1
GALT 7.1
ELKS 7.1
TDP1 7.1
galactose-1-phosphate uridylyltransferase 7.1
fukutin-related protein 7.1
member 9 7.0
NARP 7.0
NCOR1 7.0
CHMP2B 7.0
colony stimulating factor 1 receptor 6.9
SYNE1 6.9
more...
Disease
apraxia 13.5
pathological emotionality 13.5
Motor speech disorder 13.5
Pallidonigral degeneration 13.5
cortex; degeneration 13.5
Gestural apraxia 13.5
Presenile and senile dementia 13.5
Handwringing 13.5
Ideational apraxia 13.2
Constructional apraxia 13.0
Ideomotor apraxia 13.0
Oral apraxia 12.9
Verbal dyspraxia 12.9
AOA2 12.6
Progressive Nonfluent Aphasia 12.5
GD III 12.5
cerebellotrigeminal and focal dermal dysplasia 12.5
Musical alexia 12.5
Transcortical motor aphasia 12.5
aphemia 12.3
Apraxia of speech 12.2
Corticobasal degeneration 12.2
Dysprosody 12.1
Logorrhea 11.9
ALS4 11.8
acalculia 11.8
ATLD 11.5
Apraxia of gait 11.5
SCAE 11.5
astereognosis 11.4
agraphia 11.3
cognitive motor disorder 11.3
CMT2B2 11.3
Spastic ataxia 11.1
Delayed visual maturation 11.1
Finger agnosia 11.1
Balint's syndrome 11.1
transcortical aphasia 11.0
agnosia 11.0
autotopagnosia 10.9
Early Onset Cerebellar Ataxia 10.9
moria 10.9
IOSCA 10.7
XLAG 10.7
anarthria 10.6
Cogan 10.6
speech disorder 10.5
articulation disorder 10.3
disturbed concentration 10.3
agrammatism 10.2
writing disorder 10.1
SANDO 10.1
anomia 10.1
alexia 10.0
Auditory agnosia 10.0
conduction aphasia 10.0
anosognosia 9.8
Joubert syndrome 9.8
dysgraphia 9.8
Pick's disease with Pick bodies 9.8
mild memory disturbance 9.8
ATP synthase deficiency 9.8
Wernicke's aphasia 9.7
aphasia 9.7
dyscalculia 9.7
word deafness 9.7
Adenylosuccinate lyase deficiency 9.7
NPHP4 9.6
motor aphasia 9.6
AOA 9.6
Idiopathic thrombocytopenia 9.5
SCAN1 9.4
MILS 9.4
Visual agnosia 9.4
Worster-Drought syndrome 9.4
WWS 9.3
Gillespie syndrome 9.2
Parietal lobe 9.2
camptocormia 9.2
language disorder 9.2
Marchiafava-Bignami disease 9.2
Speech impairment 9.1
Cranial nerves 9.1
Cranial nerves 9.1
Pick's disease 9.1
global aphasia 9.0
Porencephaly 9.0
delayed speech 9.0
dysphasia 9.0
Primary Progressive Aphasia 9.0
echolalia 9.0
AOS 9.0
GALK 8.9
frontal lobe syndrome 8.9
mutism 8.9
abulia 8.9
cerebral degeneration 8.8
Akinetic mutism 8.8
Gerstmann 8.8
basal ganglia disease 8.7
eye movement disorder 8.7
NPHP1 8.7
specific developmental disorders 8.6
Progressive dementia 8.6
Prosopagnosia 8.6
developmental coordination disorder 8.6
progressive supranuclear palsy 8.6
atonic seizure 8.6
Landau-Kleffner syndrome 8.5
NPHP2 8.5
Cogan's syndrome 8.5
hereditary chorea 8.5
hereditary ataxia 8.4
deaf mutism 8.4
cross-dependence 8.4
Cerebellar atrophy 8.4
disorientation 8.3
amusia 8.3
Pisa syndrome 8.3
pseudobulbar palsy 8.3
49,XXXXY syndrome 8.3
Molybdenum cofactor deficiency 8.2
Frontal lobe 8.1
SCA12 8.1
choreoathetosis 8.1
CND 8.1
Kluver-Bucy syndrome 8.0
Prosody 8.0
communication disorder 8.0
progressive chorea 8.0
oxyuriasis 7.9
Pontocerebellar hypoplasia 7.7
galactosemia 7.7
GALT 7.7
pineal region tumor 7.7
Oppenheim 7.6
Ohtahara syndrome 7.6
epidemic encephalitis 7.6
cognitive disorder 7.6
SCA8 7.6
psycho-organic syndrome 7.6
Congenital hepatic fibrosis 7.6
Tapia 7.6
perseveration 7.5
FTLD 7.4
presenile dementia 7.4
amnesic syndrome 7.4
Friedreich's ataxia 7.4
Meige syndrome 7.3
Neonatal diabetes mellitus 7.3
NPHP3 7.3
memory disorder 7.3
Oropharyngeal dysphagia 7.3
specific language impairment 7.3
Rett syndrome 7.2
SCA17 7.2
Dementia with Lewy bodies 7.2
Binswanger 7.2
perception disorder 7.2
PSP 7.1
more...
Symptom
Poverty of facial expression 13.5
Apraxic 13.0
Extrapyramidal rigidity 11.9
Frozen gait 11.9
amimia 10.6
Pyramidal signs 10.5
Respiratory abnormalities 10.1
clumsiness 9.9
Retropulsion 9.8
aprosodia 9.7
hemihypesthesia 9.4
blepharospasm 9.1
Bell's phenomenon 9.1
mirror writing 8.8
dysarthria 8.8
delayed language development 8.6
Aphasic 8.3
cerebellar ataxia 8.1
astasia 8.1
visual hallucination 8.1
Motor dysfunction 8.1
ataxia 8.1
personality change 7.9
myoclonus 7.9
Swallowing problems 7.9
Kernig's sign 7.9
Plantar flexion 7.9
bradykinesia 7.7
forgetfulness 7.6
General symptoms 7.6
dystonia 7.6
Opposition 7.4
asterixis 7.3
chorea 7.2
abiotrophy 7.1
Behavioral symptoms 7.1
aphonia 7.1
prominent nose 7.1
Parkinsonian tremor 7.1
athetosis 7.0
ataxic gait 6.9
Extrapyramidal symptoms 6.9
hypotonia 6.8
monoplegia 6.7
drooling 6.7
abnormal gait 6.6
Visual disturbances 6.6
apathy 6.5
hemiplegia 6.5
memory loss 6.5
muscle rigidity 6.4
incoordination 6.4
paresis 6.2
Neurologic symptoms 5.9
arm weakness 5.9
ophthalmoplegia 5.7
spasticity 5.6
tremor 5.6
metamorphopsia 5.5
hypertonia 5.5
tonic-clonic seizure 5.4
Psychiatric symptoms 5.1
clonus 4.9
prostration 4.9
loss of taste 4.9
Involuntary Movement 4.8
motor symptom 4.6
weakness 4.5
hyperemesis gravidarum 4.4
paraparesis 4.4
ketonuria 4.4
breath holding 4.3
limb pain 4.1
leg edema 4.1
partial seizure 4.0
CSR 4.0
agitation 4.0
hepatosplenomegaly 3.9
seizures 3.9
anosmia 3.9
physical appearance 3.9
photophobia 3.8
torticollis 3.8
bloating 3.8
pallor 3.7
general problem 3.7
dysesthesia 3.6
paresthesia 3.5
blurred vision 3.4
hypersomnia 3.4
tense 3.4
catatonia 3.3
urinary frequency 3.3
productive cough 3.3
muscle stiffness 3.2
spasm 3.2
tachypnea 3.2
Mills 3.2
tingling 3.1
alexithymia 2.7
numbness 2.7
thinning 2.6
lethargy 2.6
headache 2.5
dizziness 2.5
Depressive symptoms 2.5
chronic cough 2.5
constipation 2.5
hopelessness 2.3
stridor 2.3
vertigo 2.2
dry eye 2.1
asthenia 2.1
anorexia 2.0
snoring 2.0
hepatomegaly 2.0
hoarseness 1.9
polyuria 1.9
acute abdomen 1.9
bone pain 1.9
exertional dyspnea 1.7
acute pain 1.5
cough 1.5
vomiting 1.5
sleepiness 1.4
functional recovery 1.3
cachexia 1.0
myalgia 0.8
erythema 0.8
tinnitus 0.8
arthralgia 0.7
acidity 0.6
nausea 0.5
fatigue 0.4
hypothermia 0.4
distraction 0.3
insomnia 0.1
pain 0.1
back pain -0.1
collapse -0.3
anesthesia -1.0
discomfort -1.0
discomfort -1.1
overweight -1.2
abdominal pain -1.5
diarrhea -2.3
Drug
Benserazide 7.7
PPA 6.3
CVA 6.2
Sinemet 5.7
Sinemet 5.6
Frontal 5.5
EMB 5.4
Ritalin 5.1
Botox 4.8
Pregabalin 4.7
DBS 4.7
Leucovorin 4.5
Adalimumab 4.4
Sinemet 4.4
Urokinase 4.2
Triad 4.2
Vitamin B 4.2
Phosphatidylserine 4.1
Triad 4.1
Spectrum 3.5
Spectrum 3.5
Galactose 3.4
Acyclovir 3.4
uPA 3.4
MDS 3.3
Vitamin B12 3.2
Vitamin K 3.0
CTA 3.0
Rituximab 3.0
BH4 2.9
CSF 2.2
AZT 2.1
Fluorescein 2.1
Ringer's solution 2.0
AZT 1.9
EPA 1.7
Fluorescein 1.6
Albumin 1.2
lactose 1.0
Mutagen 0.9
vitamin E 0.4
ROS 0.2
lysine -0.4
ampicillin -0.6
Monit -0.6
caffeine -0.9
Leaf -0.9
Dial -1.4
Dermatol -4.5
Enzyme
m-AAA protease 7.9
TUT 7.8
polynucleotide kinase 7.1
3'-phosphatase 7.1
galactose-1-phosphate uridylyltransferase 6.7
GalT 6.3
sepiapterin reductase 5.9
adenylosuccinate lyase 5.9
Lod 5.9
uridyltransferase 5.7
glucocerebrosidase 5.5
FAST 4.9
CYP27A1 4.4
galactokinase 4.2
GTP cyclohydrolase I 4.1
NAT 4.1
RNA ligase 4.1
DNA ligase 4.0
DNA ligase 4.0
GCA 4.0
acyl-CoA dehydrogenase 3.8
GABA transaminase 3.8
LasR 3.7
botulinum neurotoxin 3.6
SCS 3.5
phenylalanine hydroxylase 3.0
acyl-CoA dehydrogenase 3.0
DAT 2.9
TOR 2.9
ornithine transcarbamylase 2.7
choline acetyltransferase 2.4
cholinesterase 2.4
NADH dehydrogenase 2.4
STR 1.8
DNA polymerase 1.7
PARP 1.7
phosphatidylinositol 3-kinase 1.6
enolase 1.6
acetylcholinesterase 1.5
citrate synthase 1.3
MIP 1.2
RNA polymerase 1.2
ceruloplasmin 1.2
urokinase-type plasminogen activator 1.1
phosphorylase 1.0
diaphorase 0.9
creatine kinase 0.8
aldehyde dehydrogenase 0.8
GSK 0.7
cytochrome oxidase 0.4
complex I 0.3
topoisomerase 0.3
phosphodiesterase 0.3
topoisomerase 0.2
catalase 0.0
tissue plasminogen activator -0.0
thromboplastin -0.2
tyrosine hydroxylase -0.4
protein kinase -0.5
RNase -0.5
RNase -0.7
luciferase -0.8
proteasome -1.3
lactate dehydrogenase -1.4
thrombin -1.6
alkaline phosphatase -2.1
mitogen-activated protein kinase -3.1
Compound
Carbidopa-levodopa 10.5
3 PS 8.9
RD4 7.0
PSP 7.0
MOCA 6.6
IMP 6.4
Pergolide 6.2
TDP 6.1
PPA 6.0
Pyridoxine 5.9
Amytal 5.8
MEP 5.5
SSD 5.5
MEP 5.3
coenzyme Q10 5.2
Ritalin 5.2
Amitriptyline 5.1
PPA 5.1
Xenon 5.0
CoQ 4.8
DBS 4.7
EMC 4.7
tetraphosphate 4.6
TBS 4.6
Corticosterone 4.5
Sudan I 4.4
A 71 4.3
Coenzyme Q10 4.2
methyl methanesulfonate 4.2
Etanercept 4.2
Memantine 4.2
gamma-hydroxybutyric acid 4.1
Phosphatidylserine 4.1
Lamotrigine 3.9
GD3 3.9
adenylate 3.9
INT 3.8
pyridazine 3.7
pyridazine 3.7
TBI 3.7
MIT 3.7
MIT 3.7
Olanzapine 3.7
MSG 3.7
His 3.5
L-DOPA 3.5
T 1 3.5
Acyclovir 3.5
TAR 3.4
Creatine 3.4
Galactose 3.4
Bromocriptine 3.4
Coronal 3.3
Glycogen synthase 3.3
Vitamin K 3.2
Hearts 3.2
DIC 3.1
CIT 3.1
Formal 3.0
Argentine 3.0
Neuronal 3.0
Maps 3.0
Histidine 3.0
DAT 2.9
Cereb 2.9
N-acetylaspartate 2.8
Clozapine 2.7
folinic acid 2.7
HVA 2.7
Dopa 2.7
C2H2 2.7
L-carnitine 2.6
TMP 2.5
THE 2.5
TMP 2.5
TMP 2.4
Wellcome 2.4
A 1 2.4
Haloperidol 2.4
APS 2.4
CAT 2.3
CAT 2.3
Lithium 2.3
T10 2.3
GAL 2.2
DSM 2.2
CAT 2.2
Haloperidol 2.2
Parenteral 2.2
Phosphatidylinositol 2.1
Austin 2.0
CIT 2.0
TMP 2.0
FK506 2.0
A 42 1.9
valine 1.9
AAA 1.9
ADP-ribose 1.9
PAC 1.9
AMP 1.9
Guo 1.8
AZT 1.8
DHA 1.8
isoleucine 1.7
isoleucine 1.7
DTPA 1.7
EPA 1.7
6-12 1.7
A 3 1.6
PAM 1.6
PAM 1.6
DHA 1.4
DHA 1.3
Guo 1.2
piperazine 1.0
fluorine 1.0
butyric acid 1.0
DNA 0.9
ubiquinone 0.9
galactose 0.9
butyric acid 0.9
aldehyde 0.8
glutamine 0.8
ornithine 0.7
ornithine 0.7
ornithine 0.7
ornithine 0.7
ornithine 0.7
Isoproterenol 0.7
Lactate 0.7
butyric acid 0.7
Ile 0.7
Letter 0.7
Clin 0.6
Neurotol 0.6
dUTP 0.6
H2S 0.5
aldehyde 0.4
GABA 0.4
Dopamine 0.4
GABA 0.4
TCA 0.3
guanidine 0.3
GMP 0.3
molybdenum 0.2
AMPA 0.2
Lead 0.2
silver 0.2
H2O2 0.2
aspartic acid 0.1
glutamate 0.1
aspartic acid 0.1
aspartic acid -0.0
methionine -0.1
creatinine -0.1
Dec -0.1
glucose -0.2
iron -0.2
phosphate -0.2
ADP -0.2
more...