Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0003635 (apraxia)
 2,817 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of vertical oculomotor apraxia with severe memory loss and hypokinetic inertia is described in a 34-year-old woman who was taking oral contraceptives. The eye movement disorder was limited to paralysis of voluntary vertical saccades; pursuit movements, reflex eye movement, and horizontal saccades were normal. Random involuntary vertical saccades documented by electronystagmography qualified this as a true apraxia. Similar cases from the literature have in common involvement of both medial thalami, a localization supported in this case by distinctive abnormalities on CAT scan. The clinical course suggested acute infarction, possibly due to embolism, in a territory supplied by the thalamosubthalamic paramedian arteries.
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PMID:Vertical oculomotor apraxia and memory loss. 70 85

Eyelid motor impersistence is the impossibility shown by some people to maintain voluntary lid closure for a long period. This disorder is not exceptional, and the authors have seen fifteen cases over a short period of time. The phenomenon represents a form of apraxia, and occurs only when the minor hemisphere is damaged with a lesion of the parietal lobe. Diagnosis can often be confirmed by a CAT scan: of the three observations reported by the authors, two were tumors and one a thalamic hematoma. For some authors, motor impersistence is a manifestation of neglect and they include it within the general problem of interhemispheric balance.
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PMID:[Eyelid motor impersistence]. 667 56

A CAT scan was recorded from 123 patients with left hemisphere damage from stroke. They were divided into four groups according to presence or absence of ideomotor apraxia and length of illness (15 to 90 days and over 90 days). The lesions were mapped and compared in the four experimental groups for anteroposterior dimension, lesion depth--deep-seated lesions deing separated from lesions with a superficial component--and position with respect to the Sylvian fissure for lesions encroaching on the surface. In the anteroposterior dimension there is no material difference in the distribution of the lesions with respect to length of illness. Moreover, any difference is hardly detectable between the profiles for patients with and without ideomotor apraxia except for the higher frequency of deep lesions in the non-apraxic group. The same holds true for "small" lesions.
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PMID:Is ideomotor apraxia the outcome of damage to well-defined regions of the left hemisphere? Neuropsychological study of CAT correlation. 735 49

Fifty patients with periventricular hypodense lesions in cerebral CAT (leucoaraiosis) were included in a prospective study. All of them were intensively evaluated considering both the clinical and neuropsychological aspects. Fifteen of these patients were diagnosed of dementia following the criteria proposed by Bennett et al for Binswanger's disease. The group of patients with dementia was compared with the rest of patients with leucoaraiosis from the radiological, semiological and neuropsychological aspects; the incidence of vascular risk factors and the score obtained in the Ischemic Scale were also compared. We found that the patients with dementia have, in the CAT study, more severe periventricular lesions than the rest of patients. We have not found any significative differences in the incidence of vascular risk factors. Deambulation disorders, constructive apraxia and visual-perceptive disorders were the symptoms more strongly related with dementia, even tough only the latter two showed this relationship in the statistical multivariant analysis. Differences in the score of test and scales were highly significant. We think that Bennett's criteria are of great value for the clinical diagnosis of Binswanger's disease.
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PMID:[Clinical diagnosis of Biswanger's disease]. 846 24