Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003635 (apraxia)
 2,817 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An enigma in understanding the mechanism of motor apraxia is why patients with disease restricted to the left hemisphere cannot imitate motions with the left hand despite intact visual motor apparatus. Liepmann suggested that motor memories are stored in the left hemisphere and that in apraxia these engrams are either destroyed or separated from the right hemisphere. If Liepmann's hypothesis is correct, then, in addition to poor performance on commands and imitation, there should be poor performance in a motor task. To ascertain if there is a motor defect of the non-paretic hand of apraxic patients, twenty apraxic patients were given a rapid finger tapping test and their performance was compared with the left hand performance of aphasic right hemiparetic non-apraxic controls. The aptaxic group performed this task significantly slower than the control group, thereby giving support to Liepmann's hypothesis of apraxia.
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PMID:A tapping test in apraxia. 120 66

Dyspraxia is an enigma to many people, both professional and lay alike--what is it, how does it relate to developmental coordination disorder and associated conditions, how common is it, how is it recognised and diagnosed and how should it be managed? This article attempts to unravel this enigma by: dealing with the terminology of coordination difficulties from the "clumsy child syndrome" through "dyspraxia" to "developmental coordination disorder (DCD)"; briefly examining the debate as to whether dyspraxia or DCD should be regarded as a medical or social disorder; discussing the differential diagnosis of dyspraxia or DCD; considering the assessment of children with dyspraxia or DCD; reviewing the range of current treatment approaches in the UK.
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PMID:Dyspraxia or developmental coordination disorder? Unravelling the enigma. 1751 23