Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0003635 (
apraxia
)
2,817
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 57-year old man with chronic alcoholism presented with
apraxia
of speech and disturbance of consciousness. He had a history of gastrectomy and had been drinking alcohol. The symptoms improved with administration of thiamine, but he later developed
diarrhea
and delirium, and died approximately 40 days after the onset. Autopsy findings were consistent with Wernicke's encephalopathy and pellagra encephalopathy. Furthermore, laminar cortical necrosis with vacuoles and astrocytosis was found in the second and third layers of the bilateral frontal cortices, suggesting Morel's laminar sclerosis. The lesions were mainly located in the bilateral primary motor cortices. Involvement of the lower part of the left primary motor cortex may be associated with
apraxia
of speech in our case.
...
PMID:Morel's laminar sclerosis showing apraxia of speech: distribution of cortical lesions in an autopsy case. 1956 7
