Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0003615 (appendicitis)
4,439 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 23-year-old man without a history of tuberculosis presented with right lower abdominal pain and a fever. An increased inflammatory response was found, and abdominal computed tomography showed a diffuse enlargement and wall thickening in the appendix. An ileocecal abscess and perforating appendicitis were suspected. Therefore, an emergency operation was performed. The surgery revealed a diffuse enlargement with adhesion to the retroperitoneum, which was suspected to be a neoplastic lesion of the appendix, thus an ileocecal resection including the appendix was performed. A histopathological examination revealed a number of epithelioid granulomas having Langerhans giant cells with caseous necrosis in the appendix, in addition to many granulomas without caseous necrosis in the regional lymph nodes. No tubercle bacilli were detected by Ziehl-Neelsen staining. Further examination revealed no tubercular lesions in other organs, thus leading to the diagnosis of primary tuberculosis of the appendix. This is an extremely rare disease reported in Japan.
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PMID:Primary tuberculosis of the appendix in a young male patient: report of a case. 2058 21

Tubercular appendicitis is the appendicular infection with tubercular bacillus, which develops as an extension of ileocecal infection. Tuberculosis is either primary or secondary. Primary tuberculosis of the appendix is uncommon. Diagnosis is made by histopathological examination of the resected appendix. We report a rare case of tubercular appendicitis diagnosed on histopathology. Primary Tuberculosis of the appendix is a clinical rarity. Hence, it is being reported. The case report in this study emphasizes the importance of submitting all appendectomy specimens for histopathological examination and the occurrence of primary tuberculosis at a rare site, such as the appendix.
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PMID:Primary tuberculosis of the appendix: A common disease with rare location - a rare case report from rural India. 3247 5