Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003129 (Anoxia)
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Human Gene/Protein
Stomatin-like 1 15.8
PN1 9.8
DRP-1 9.8
Pannexin-1 9.7
Phosphoglucomutase 9.4
PFK-1 9.3
GOX 9.2
PRKAA1 9.0
DOD 8.9
Cytoglobin 8.9
PFK-2 8.8
NFATc4 8.7
ALOX5 8.7
6-phosphofructo-2-kinase 8.7
Aryl hydrocarbon hydroxylase 8.5
InsP3R1 8.5
NFAT5 8.4
IP3R1 8.3
TCP1 8.3
NFATc3 8.1
HIF-1beta 8.0
TRPM7 7.9
lactic acid dehydrogenase 7.9
GDP dissociation inhibitor 7.7
NaN 7.7
6-phosphofructokinase 7.7
mGlu1 7.7
P31 7.6
gag protein 7.6
oxidized low-density lipoprotein receptor 7.5
ACO 7.4
TRPC5 7.4
BPP 7.4
P23 7.4
TRPM2 7.4
Hsp20 7.4
cytoglobin 7.3
PGR 7.3
TRPC6 7.3
Glucose-6-phosphate dehydrogenase 7.3
neuroglobin 7.2
sodium pump 7.2
guanylate kinase 7.2
Pyruvate dehydrogenase 7.1
Math1 7.1
xanthine dehydrogenase 7.1
glycogen phosphorylase 7.1
AOX 7.0
BOC 7.0
PP2C 7.0
mGlu5 7.0
Hsp40 7.0
phosphoglycerate mutase 6.9
PST 6.8
ACH 6.8
glutathione peroxidase 4 6.7
TRPA1 6.7
phosphofructokinase 6.7
xCT 6.7
GRP94 6.6
calmodulin-dependent protein kinase IV 6.6
apyrase 6.6
AIR 6.6
EB1 6.5
glycerol kinase 6.5
P28 6.5
glutathione synthetase 6.4
HSF1 6.4
LIP 6.4
N-acetyl-beta-glucosaminidase 6.3
HIF-1 6.2
asp 6.2
PAG 6.2
ACPD 6.1
elongation factor 2 6.1
P60 6.1
adenosinetriphosphatase 6.1
glycerol-3-phosphate dehydrogenase 6.1
TRP 6.1
FDP 6.1
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Disease
Neonatal anoxia 12.0
Worster-Drought syndrome 11.7
cerebral ischemia/hypoxia 11.4
brain anoxia 10.1
Infections of the central nervous system 9.3
Myositis ossificans 8.8
Photosensitization 8.7
Robinow syndrome 8.3
hypoglycemic coma 7.8
BPP 7.6
amnesic syndrome 7.4
neonatal asphyxia 6.9
LIP 6.9
diplegia 6.9
Diaphragm 6.8
laryngospasm 6.7
alkalosis 6.7
Colon cancer 6.6
PMT 6.6
respiratory acidosis 6.3
attention deficit disorder 6.1
hyaline membrane disease 5.9
trichotillomania 5.9
venous stasis 5.9
ADH 5.7
refractory anemia 5.6
renal ischemia 5.5
toxemia 5.5
priapism 5.4
achondroplasia 5.4
severe mental retardation 5.3
keratopathy 5.3
premature rupture of membranes 5.2
premature labor 5.1
ischemia 5.0
Luminal 5.0
amnesia 5.0
lactic acidosis 4.8
cor pulmonale 4.7
bronchopneumonia 4.7
paracoccidioidomycosis 4.6
prematurity 4.6
HSP 4.5
ventricular fibrillation 4.5
Bladder 4.5
Bladder 4.5
Bladder 4.5
atrioventricular block 4.5
chronic granulomatous disease 4.4
anaphylaxis 4.4
TOC 4.4
tetraplegia 4.3
sympathomimetic 4.3
BLM 4.2
cerebral palsy 4.2
Wright 4.0
encephalopathy 4.0
TCP 4.0
coronary occlusion 4.0
hyperbilirubinemia 3.9
hyperuricemia 3.9
gangrene 3.9
myocardial ischemia 3.9
coma 3.9
dehydration 3.9
meningoencephalitis 3.8
cerebral ischemia 3.8
ADHD 3.7
brain edema 3.7
MRS 3.6
SCH 3.5
gout 3.5
leiomyoma 3.5
depression 3.4
decubitus 3.4
Pituitary 3.4
adult respiratory distress syndrome 3.4
ARF 3.3
pulmonary hypertension 3.2
paraplegia 3.2
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Symptom
Anoxia 15.8
Gasping 9.9
monoplegia 9.0
Excitability 8.5
rundown 6.8
drooling 6.4
hyperoxia 5.8
hypercapnia 5.4
cyanosis 4.9
twitching 4.8
flushing 4.2
dysarthria 3.9
chills 3.8
starvation 3.2
exhaustion 3.1
spasm 3.0
hypothermia 2.7
collapse 2.6
seizures 2.5
fatigue 2.5
agitation 2.3
erythema 2.1
acidity 1.9
ataxia 1.9
tremor 1.6
respiratory distress 1.6
angina 1.5
anesthesia 0.7
pain -2.2
Drug
Lidoflazine 10.4
Diamox 8.5
KCL 7.7
Pregnenolone 7.6
Ouabain 7.1
Apomorphine 6.5
Amiloride 6.3
Amiloride 6.0
Fructose 5.9
CoCl2 5.5
CoCl2 5.5
Methylene blue 5.5
BLM 5.4
ETA 5.4
Alanine 5.4
Ringer's solution 5.4
MgSO4 5.2
Theophylline 4.8
Indomethacin 4.8
NADH 4.6
Fluorescein 3.9
niacin 3.9
p75 3.9
caffeine 3.7
ascorbate 3.3
Nephron 3.3
CaCl2 3.2
CaCl2 3.2
ROS 3.2
CaCl2 3.1
Leaf 3.0
nitroglycerin 2.7
CTX 2.5
vitamin E 1.7
lysine 1.0
Cardiovasc 0.8
Dermatol -2.2
Enzyme
oleate desaturase 9.6
6-phosphofructo-2-kinase 9.0
EC 2.7.7.9 8.9
ubiquinol-cytochrome c oxidoreductase 8.4
eEF2 kinase 7.9
aequorin 7.3
PMT 7.2
succinyl-CoA synthetase 7.1
lactic acid dehydrogenase 7.0
lactic acid dehydrogenase 6.9
calcium pump 6.8
NADH-cytochrome b5 reductase 6.8
phosphofructokinase 6.7
xanthine dehydrogenase 6.5
fumarate reductase 6.5
glutathione synthetase 6.4
phosphorylase 6.4
glycerol kinase 6.3
lactic acid dehydrogenase 6.2
apyrase 6.2
caspase-2 6.2
sucrose synthase 6.2
caspase-2 6.2
PST 6.1
pyruvate decarboxylase 6.1
adenosine kinase 6.0
cGMP phosphodiesterase 5.9
SCS 5.8
ADH 5.7
nitrate reductase 5.5
nitrate reductase 5.5
nitrate reductase 5.5
nitrate reductase 5.5
nitrate reductase 5.5
nitrate reductase 5.5
pyruvate kinase 5.5
phosphoglucomutase 5.4
dopamine beta-hydroxylase 5.4
PGM 5.4
ascorbate peroxidase 5.4
6-phosphogluconate dehydrogenase 5.3
6-phosphogluconate dehydrogenase 5.3
phosphoglucose isomerase 5.1
pyruvate dehydrogenase 5.1
succinic dehydrogenase 5.1
pyruvate dehydrogenase 5.0
hexokinase 5.0
glycerol-3-phosphate dehydrogenase 5.0
glycerol-3-phosphate dehydrogenase 5.0
pyruvate dehydrogenase 5.0
prostaglandin synthetase 5.0
nitrite reductase 5.0
nitrite reductase 4.9
nitrite reductase 4.9
lactate dehydrogenase 4.9
glutamate decarboxylase 4.7
chaperonin 4.7
glyceraldehyde-3-phosphate dehydrogenase 4.7
glyceraldehyde-3-phosphate dehydrogenase 4.7
glyceraldehyde-3-phosphate dehydrogenase 4.6
creatine kinase 4.6
diamine oxidase 4.6
PKG 4.5
xanthine oxidase 4.4
glyceraldehyde-3-phosphate dehydrogenase 4.4
ribonucleotide reductase 4.3
ribonucleotide reductase 4.3
alcohol dehydrogenase 4.2
isocitrate dehydrogenase 4.2
glyceraldehyde-3-phosphate dehydrogenase 4.2
aldose reductase 4.1
isocitrate dehydrogenase 4.1
aldolase 4.1
monoamine oxidase 4.0
arginase 4.0
glucose-6-phosphate dehydrogenase 3.9
cathepsin D 3.8
phosphoenolpyruvate carboxykinase 3.8
phosphoenolpyruvate carboxykinase 3.8
guanylate cyclase 3.8
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Compound
pentyl hexanoate 14.2
pentyl butyrate 14.2
C8H16O2 14.2
C14H14N4 12.1
2,4-pyridinedicarboxylic acid 11.6
Mannoheptulose 10.8
Pyrithiamine 10.3
Betanin 10.1
pentyl acetate 9.7
Succinylacetone 9.5
Vitexin 9.2
Tyrosol 9.2
2,4-DP 9.0
Dibucaine 8.9
2-methyl-1-butanol 8.9
Tolazoline 8.9
Chlorpheniramine 8.7
Chlorpheniramine 8.6
Oleuropein 8.1
Cyclopiazonic acid 8.1
SITS 8.1
Calyculin A 8.1
Chelerythrine 8.0
Chelerythrine 8.0
Diazoxide 8.0
pentanal 7.8
Saccharin 7.8
pentanal 7.8
Pregnenolone 7.6
Phlorizin 7.5
1-pentanol 7.3
Propidium iodide 7.2
MCE 7.2
Methysergide 7.2
PMT 7.2
DIDS 7.2
AIR 7.1
Ouabain 7.1
Acetazolamide 7.1
Nicorandil 7.1
fructose-6-P 7.0
Veratridine 7.0
ETH 6.9
Tetrodotoxin 6.9
6-phosphogluconate 6.8
Tetraethylammonium 6.8
5-methylisoxazole 6.7
MIA 6.6
1-hexanol 6.6
Nordihydroguaiaretic acid 6.5
8-Br-cGMP 6.5
Dithiothreitol 6.4
ETH 6.4
phosphocreatine 6.3
CNQX 6.3
APV 6.3
Adenine 6.3
Physostigmine 6.3
Amiloride 6.3
cyanide 6.2
BaCl2 6.2
ethanesulfonic acid 6.2
ethanesulfonic acid 6.2
PAG 6.2
Dithiothreitol 6.2
Cytochalasin B 6.2
cyclopentyl 6.0
Pyruvate 5.9
FDP 5.9
Fructose 5.8
Nitroglycerin 5.8
hippurate 5.8
PPi 5.8
Eosin 5.8
Ryanodine 5.8
PPI 5.8
DNP 5.7
Wortmannin 5.7
Carnitine 5.7
Glycogen 5.6
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