Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003123 (anorexia)
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Human Gene/Protein
ACRC 9.6
GFRAL 9.5
melanoma associated antigen (mutated) 1 9.2
AMICA1 9.2
HF12 9.2
IBtk 9.2
IFN-alpha 5 8.7
STC2 protein 8.2
FAM19A5 8.2
Interleukin-1 receptor type I 7.9
5-HT-2C 7.9
CAMKK 7.6
aspartate aminotransferase 1 7.6
Tryptophan hydroxylase 1 7.6
KA21 7.6
Nucleobindin 2 7.5
adenylate cyclase 6 7.4
SAPAP3 6.9
neuropeptide Y1 receptor 6.9
Ret proto-oncogene 6.9
MRX34 6.8
molybdenum cofactor sulfurase 6.8
orexin receptor 2 6.8
SMEI 6.8
nucleobindin 6.7
complex I assembly factor 6.7
GA II 6.7
PHLDA3 6.7
CDHP 6.6
SLACK 6.6
RHBDF2 6.6
CML28 6.6
T cell receptor gamma chain 6.6
cocaine- and amphetamine-regulated transcript 6.6
MCG 6.6
melanocortin 4 receptor 6.5
Ucn III 6.5
NADH-coenzyme Q reductase 6.5
N61 6.5
interferon alpha A 6.5
TP53INP2 6.5
melanocortin-4 receptor 6.5
ghrelin 6.5
MC3 6.4
SLITRK1 6.4
urocortin 3 6.4
stresscopin 6.4
GIL 6.4
NCKX4 6.4
ghrelin receptor 6.3
hSyn 6.3
mucin 3 6.3
CUBN 6.3
EAT 6.3
Tonicity-responsive enhancer binding protein 6.3
SLC30A2 6.3
APS2 6.3
Ghrelin 6.2
PYY3 6.2
obestatin 6.2
ob protein 6.2
ALG12 6.2
PKDL 6.2
methylmalonyl-CoA epimerase 6.2
CRF2 6.2
Insulin-like peptide 5 6.2
gamma-seminoprotein 6.2
Kv9.3 6.1
drebrin E 6.1
TNF-a 6.1
Liver-expressed antimicrobial peptide 2 6.0
agouti 6.0
RXFP4 6.0
HLA-DNA 6.0
prostaglandin D2 receptor 6.0
MuRF 6.0
PAPSS2 6.0
parathyroid hormone-like hormone 5.9
JAM3 5.9
NYGGF4 5.9
more...
Disease
infected skin cyst 11.2
infected skin cyst 11.2
Tuberculosis of mesenteric lymph nodes 11.2
Coryzal symptoms 11.2
Pancreatic islet cell adenoma 11.2
melanemia 11.2
Marasmic kwashiorkor 11.2
Papovavirus infection 11.2
gastrectasis 11.2
Acute iridocyclitis 11.2
anemia; progressive 11.2
Equine ehrlichiosis 10.6
oak poisoning 10.6
Chronic frontal sinusitis 10.2
Trichophagia 10.2
Anxious personality 10.2
Renal function disorder 10.2
Carcinomatous ascites 10.2
Cancer anemia 10.2
adenocarcinoma of the extrahepatic bile duct 10.2
ceruminosis 10.2
Meningococcal pneumonia 10.2
Acute cholestatic hepatitis 10.2
Traumatic reticuloperitonitis 10.2
Nodular panniculitis 10.2
Gallbladder infection 10.2
LAMN 10.2
Mesenchymal Hamartoma of the Liver 10.2
Abomasal dilatation 10.2
Hydrallantois 9.9
Jejunal hemorrhage 9.6
Retrocecal appendicitis 9.6
AIDS complication 9.6
Disseminated cutaneous sporotrichosis 9.6
Disseminated Mycobacterium kansasii infection 9.6
Acute gastric mucosal lesion 9.6
Necrotizing colitis 9.6
Dientamoebiasis 9.6
Terminal Cancer 9.6
Gallbladder mucocele 9.6
Cholangiohepatitis 9.6
swelling of the pituitary gland 9.4
Regenerative anemia 9.4
Eosinophilic gastritis 9.4
Typhoid and paratyphoid fevers 9.2
Gastric hypomotility 9.2
Flu-like syndrome 9.2
Cervical Carcinoma 9.2
Clostridium perfringens type D enterotoxaemia 9.2
Hepatic coccidiosis 9.2
Cancer cachexia 9.1
Silent myocardial infarction 8.9
Chronic cholangitis 8.9
Acute dermatitis 8.9
syringitis 8.9
Visceral gout 8.9
Erosive duodenitis 8.9
EPO resistant anemia 8.9
appetite disorder 8.9
Caprine brucellosis 8.9
Isolated ACTH deficiency 8.9
Myxoglobulosis 8.9
Hypertonic dehydration 8.9
Chronic pulmonary histoplasmosis 8.9
Retinal microaneurysms 8.9
TINU 8.9
Endocardiosis 8.6
stage III testicular cancer 8.6
Clostridium tetani infection 8.6
Intestinal capillariasis 8.6
Hepatozoonosis 8.6
Inguinal lymphadenopathy 8.6
Fulminant amoebic colitis 8.6
Walker carcinoma 256 8.5
Systemic sclerosis sine scleroderma 8.4
Pseudohyperparathyroidism 8.4
nutmeg liver 8.4
Superficial gastritis 8.4
Vegetative endocarditis 8.4
Leser-Trelat 8.4
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Symptom
Girdle pain 11.2
Temporal headache 11.2
Numbness of fingers 11.2
anorexia 11.2
change in abdominal size 11.2
Poverty of facial expression 11.2
Upper abdominal discomfort 11.2
burning sensation in eye 11.2
pain in the umbilical region 10.2
swollen eye 9.6
Appetite suppression 9.4
Gastrointestinal signs and symptoms 9.4
Intermittent diarrhea 9.2
Rovsing's sign 9.2
Auspitz's sign 8.9
Acute vomiting 8.9
adipsia 8.7
lethargy 8.4
change in bowel movements 8.4
Giddiness 8.4
McBurney's point 8.4
cachexia 8.4
lassitude 8.3
febricula 8.3
liver pain 8.2
Poor weight gain 8.1
decreased skin turgor 8.0
emaciation 8.0
epigastric distress 7.9
asthenia 7.9
dysorexia 7.9
Chills and fever 7.9
Morning headache 7.9
Abdominal tenderness 7.8
Early satiety 7.7
Homan's sign 7.6
nausea 7.5
night sweats 7.4
No vomiting 7.4
labored breathing 7.4
upset stomach 7.3
prostration 7.3
vomiting 7.2
jaundice of the skin 7.2
inanition 7.1
hyperosmia 7.0
Mucosal hyperplasia 6.9
General symptoms 6.9
dark urine 6.8
polydipsia 6.8
nasal discharge 6.7
Ill 6.7
intestinal angina 6.7
decreased appetite 6.7
belching 6.6
Diarrhea and vomiting 6.6
abdominal fullness 6.6
generalized abdominal pain 6.6
bloating 6.6
nausea and vomiting 6.6
tenesmus 6.5
enanthema 6.5
pallor 6.5
epigastric pain 6.5
abdominal discomfort 6.4
Howship-Romberg sign 6.4
chills 6.4
Flu-like symptoms 6.4
Chronic abdominal pain 6.3
giddiness 6.3
giddiness 6.3
Gastrointestinal symptoms 6.3
abdominal cramps 6.3
polyuria 6.3
abnormal taste 6.3
left lower quadrant pain 6.3
Functional constipation 6.3
sinus pain 6.3
constipation 6.3
hypoproteinemia 6.2
more...
Drug
Nelumbo seed 11.2
Miproxifene phosphate 11.2
Emitefur 10.2
Tiopinac 10.2
Diethylpropion hydrochloride 10.2
Tandospirone citrate 9.6
Deracoxib 9.2
Dirlotapide 9.2
Solu-medrol 8.9
Afema 8.9
Oxilorphan 8.6
Alesion 8.6
IHMS 8.4
Serzone 8.4
Calcium hopantenate 8.2
Rubitecan 8.2
Zaltoprofen 8.0
Cloxazolam 8.0
Bupleurum root 8.0
Stiripentol 8.0
Lonafarnib 8.0
Torisel 7.9
Nabilone 7.8
Carzelesin 7.7
Carmofur 7.5
Navoban 7.5
Navoban 7.5
Gamithromycin 7.5
Ilmofosine 7.5
Symlin 7.5
Brofaromine 7.4
Mazindol 7.1
Concerta 7.1
Diethylpropion 7.1
Safingol 7.0
Tranxene 6.9
FML 6.9
Metreleptin 6.8
Alfaprostol 6.8
Pirenperone 6.7
Tanespimycin 6.6
Kytril 6.6
Cognex 6.6
Febantel 6.6
Kytril 6.5
Ibritumomab tiuxetan 6.5
Butorphanol tartrate 6.5
Uzel 6.5
Intron A 6.3
Alphagan 6.3
Vindesine 6.3
Rufinamide 6.3
Leucovorin 6.3
Vindesine 6.3
Irofulven 6.2
Reminyl 6.2
Menogaril 6.2
Tryptophane 6.2
Intron A 6.1
Interferon beta-1a 6.1
Metoclopramide hydrochloride 6.1
Artist 6.1
Intron A 6.1
Pirfenidone 6.1
Proleukin 6.1
Nexavar 6.0
Alphagan 6.0
Jujube 6.0
Ipecac 6.0
Avilamycin 5.9
Narasin 5.9
Vorozole 5.9
hCRH 5.9
Doxifluridine 5.9
Pleconaril 5.9
Ixabepilone 5.8
Dexfenfluramine 5.8
Axitinib 5.7
Vorinostat 5.7
Vatalanib 5.7
more...
Enzyme
ABA2 5.7
pyroglutamyl peptidase II 5.6
TUT 5.5
MSAS 5.3
MTD 5.1
aspartate semialdehyde dehydrogenase 5.1
dihydropyrimidine dehydrogenase 4.8
glycerophosphodiester phosphodiesterase 4.7
adenine deaminase 4.5
dihydropyrimidine dehydrogenase 4.5
aspartate aminotransferase 4.2
branched-chain alpha-keto acid dehydrogenase 4.2
tripeptidase 4.1
alanine aminotransferase 4.1
transketolase 4.0
AST 3.8
biotinidase 3.6
Lod 3.6
angiotensin-converting enzyme 2 3.5
BAT 3.5
sorbitol dehydrogenase 3.4
gamma-glutamyl transpeptidase 3.3
monoacylglycerol lipase 3.3
inositol 3-kinase 3.3
3-mercaptopyruvate sulfurtransferase 3.3
thymidine phosphorylase 3.2
fumarylacetoacetate hydrolase 3.0
asparaginase 2.9
alkaline phosphatase 2.9
ADH 2.9
phosphoglycerate dehydrogenase 2.9
creatine kinase 2.8
GMT 2.8
propionyl-CoA carboxylase 2.8
propionyl-CoA carboxylase 2.7
farnesyltransferase 2.7
isoamylase 2.6
CEP 2.6
lactic acid dehydrogenase 2.6
mannosidase II 2.6
21-hydroxylase 2.6
TACE 2.5
methylmalonyl-CoA mutase 2.5
GABA transaminase 2.5
lysine decarboxylase 2.5
calpain 3 2.4
lactate dehydrogenase 2.4
CGT 2.4
lactic acid dehydrogenase 2.3
lactonase 2.3
Rex 2.3
indoleamine 2,3-dioxygenase 2.3
lactic acid dehydrogenase 2.3
acetyl-CoA carboxylase 2.3
DMT 2.3
cytidine deaminase 2.2
farnesyltransferase 2.2
dihydroorotate dehydrogenase 2.2
dihydroorotate dehydrogenase 2.2
CPT 2.2
aldehyde reductase 2.2
thymidylate synthase 2.2
DOPA decarboxylase 2.1
cystathionine gamma-lyase 2.1
CPT 2.1
glutamate dehydrogenase 2.1
glutamate dehydrogenase 2.1
p80 2.1
CEP 2.1
glutamate dehydrogenase 2.1
ceruloplasmin 2.0
ornithine transcarbamylase 2.0
CPT 2.0
lipoprotein lipase 2.0
tryptophan hydroxylase 2.0
CCS 2.0
xanthine dehydrogenase 1.9
CPS 1.9
cholinesterase 1.9
GTP cyclohydrolase I 1.8
more...
Compound
Torquatone 11.2
Ergosine 9.6
Ammelide 9.2
Myristoleic acid 8.9
C15H20O3 8.6
Ethynodiol diacetate 8.6
Bruceantin 8.4
1-phenyl-2-butanone 8.4
D-Carnitine 8.0
Amdro 7.7
Diethylpropion 7.7
4-quinolinecarboxylic acid 7.7
Furaltadone 7.6
C17H19NO3 7.6
Phenylpropanolamine 7.5
Phenylpropanolamine 7.5
Catharine 7.5
Indicine N-oxide 7.5
Hydrazine sulfate 7.3
2-phenyl-1,3-propanediol 7.2
Merbarone 7.1
Guanidinosuccinic acid 7.1
Aminorex 7.1
Norfenfluramine 7.0
Nedaplatin 7.0
Fenfluramine 7.0
RBr 6.9
Norfenfluramine 6.9
Neomycin sulfate 6.9
Dihydrotachysterol 6.9
PR-toxin 6.9
Histidyl-proline diketopiperazine 6.9
Neomycin sulfate 6.8
Isometamidium chloride 6.6
Felbamate 6.6
Sodium vanadate 6.4
Furazolidone 6.4
(+)-Amphetamine 6.4
Versene 6.4
Phosphate ion 6.3
Zonisamide 6.3
MK-329 6.3
Topiramate 6.3
Leucovorin 6.3
DMAP 6.2
4-hydroxybenzonitrile 6.2
Cyproheptadine 6.2
Sulfapyridine 6.2
Tetrahydrocannabinol 6.1
Carboquone 6.1
MCNU 6.1
Olsalazine 6.0
Lentizol 6.0
Fostriecin 6.0
Niguldipine 6.0
Mequitazine 5.9
Dolasetron 5.9
Mequitazine 5.9
Mequitazine 5.9
Mequitazine 5.9
Oleandrin 5.9
Cinoxacin 5.9
Oleoylethanolamide 5.9
Tegafur 5.8
Carboquone 5.8
Carboquone 5.8
Carboquone 5.8
Carboquone 5.8
Fludarabine phosphate 5.8
Iproniazid 5.8
Papaverine hydrochloride 5.8
Sulfobromophthalein 5.7
Pingyangmycin 5.7
Prednimustine 5.7
Deoxynivalenol 5.7
Pyrithiamine 5.6
Nialamide 5.6
Tocainide 5.6
1-(3-chlorophenyl)piperazine 5.6
Meclizine 5.6
more...