Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0003090 (arthrodesis)
 8,374 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ten scapulothoracic arthrodesis procedures were performed in six patients with facioscapulohumeral muscular dystrophy in order to improve considerably restricted activities of daily living. Four of these procedures were bilateral. The duration of follow-up ranged from 28 to 120 months. All patients reported improved function in activities of daily living. Active shoulder abduction was improved by an average of 44 degrees, and active flexion increased by 56 degrees. There was no deterioration in improved upper limb function with time. Complications included pneumothorax, atelectasis, pleural effusion and re-exploration for a segment of retained drain.
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PMID:Scapulothoracic arthrodesis for patients with facioscapulohumeral muscular dystrophy. 1009 65

Facioscapulohumeral muscular dystrophy is a progressive disorder characterized by weakness in the muscles of the face, shoulder girdle and upper limbs, and variable lower extremity weakness. The muscles that stabilize the scapula are significantly weak, although the deltoid usually is preserved. With attempted shoulder abduction, the unstable scapula protrudes, elevates, and internally rotates. Scapulothoracic arthrodesis stabilizes the scapula and improves active range of motion and function of the shoulder. Appropriate scapular positioning on the chest wall has been described previously. The current authors review a neurovascular complication after scapulothoracic arthrodesis in which the scapula was positioned as described in the literature. Immediate repositioning resulted in an excellent long-term outcome. Previous recommendations as to scapular position must be taken simply as guidelines. Intraoperative monitoring of neurovascular function in the upper extremity should prevent this complication.
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PMID:A neurovascular complication after scapulothoracic arthrodesis. 1261 53

Many patients with facioscapulohumeral muscular dystrophy eventually have instability of the scapula resulting from weakness of the scapula stabilizers. A subset of patients, however, has sufficient strength in the supraspinatus and deltoid muscles to flex and abduct the arm, if the scapula has been stabilized. The purpose of this study is to report the clinical results of six patients (9 shoulders) that underwent scapulothoracic arthrodesis for the treatment of limited shoulder motion and scapular winging caused by facioscapulohumeral muscular dystrophy. The average preoperative active flexion was 71 degrees , which improved to 109 degrees at the last follow-up. The UCLA Shoulder Score also rose from 18.4 points to 27.9 points at the last follow-up. All patients did well in activities of daily living after the procedure. Scapulothoracic arthrodesis is considered a successful treatment method for facioscapulohumeral muscular dystrophy, as it improves appearance, function, and tolerance to exercise.
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PMID:Long-term results of scapulothoracic arthrodesis of facioscapulohumeral muscular dystrophy. 1683 49

We introduced a new scapulothoracic arthrodesis technique in 6 patients (2 bilaterally) with winging of the scapula due to facioscapulohumeral muscular dystrophy from 1984 to 2000. The procedure involved a combination of plating and wiring techniques. The indications were symptomatic winging, limitation of active shoulder motion, pain, and impaired daily living activity. Our objective was to improve motion, strength, and performance of activities of daily living, as well as to provide pain relief. As a result of the technique, active motion improved in all patients, flexion improved from 64 degrees to 104 degrees, and abduction improved from 67.5 degrees to 112.5 degrees. The only complication was a hemothorax in a bilateral case that was easily treated. The length of follow-up averaged 32.5 months (14-55 months), and results did not change with time.
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PMID:Scapulothoracic arthrodesis for winged scapula due to facioscapulohumeral dystrophy (a new technique). 1692 55

This update begins with muscle manifestations of coronavirus 2019. They may include myalgias and elevations in serum creatine kinase. It is unknown whether there is direct muscle invasion and how often the critically ill have muscle sequelae. Regarding autoimmune myopathies, a retrospective study of statin-induced necrotizing myopathy is covered. A relatively large proportion of patients had normal strength at presentation. Examples of dermatomyositis associated with immune checkpoint inhibitors are provided including one with cytokine storm. A report of juvenile dermatomyositis with severe abdominal complications is noteworthy. Two articles address unusual associations with inclusion body myositis, namely, spinocerebellar ataxias and granuloma myositis. In the category of muscular dystrophies, a relatively large single center study of the outcome of scapulothoracic arthrodesis for facioscapulohumeral muscular dystrophy is discussed and a article on anoctaminopathies with pauci- or asymptomatic hyperCKemia.
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PMID:What is in the Myopathy Literature? 3321 92