Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0003090 (arthrodesis)
 8,374 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of authochthonous mycetoma with Petriellidium boydii as the causal agent, located in the third distal of the lower left leg is reported. The patient was a 35 year old male without any associated pathology. It is assumed that the infecting organism entered the tissues through a lesion caused a few years previously during a traffic accident. On admittance patient was found to have two fistulas on the upper part of the external malleolus from which pus with small yellow granules measuring 1 to 1.5 mm in diameter discharged. Fungus was repeatedly isolated in pure culture in all media in which is was sown. Mycological study of the isolated fungus and histopathology of the lesion are presented. The fungus proved in vitro to be sensitive to miconazole nitrate with minimal inhibitory concentration and minimal fungicide concentration values of less than 0.1 microgram/ml. The third distal of the peroneal bone was excised and arthrodesis of the ankle practiced as conservative treatment and miconazole administered intravenously, Eighteen months later clinical evolution is satisfactory.
 ...
PMID:[Autochthonous mycetoma caused by Petriellidium boydii (author's transl)]. 719 7

The aim of this study was to investigate the effect of gallium nitrate solution, an anti-resorption substance, when applied for root surface treatment in rat teeth submitted to delayed replantation, in order to inhibit the root resorption process and enhance repair. For such purpose, 20 maxillary right central incisors of rats were randomly assigned to 2 groups (n=10). In group I, root surface was treated with 10-4M gallium nitrate solution for 20 min, while in group II root surface was treated with 2% sodium fluoride for 20 min. All root canals were filled with a calcium hydroxide-based paste. At 15 and 60 days after replantation, the animals were killed and the specimens were processed in laboratory for light transmission microscopy. In both groups, there was mild occurrence of ankylosis and root resorption. The connective tissue formed at the periodontal ligament area was arranged parallel to the root in most specimens in both groups and presented signs of inflammation. In group I, there was periodontal pocket formation in all specimens at 60 days, revealing lack of repair. These findings contraindicate the use of gallium nitrate for root surface treatment of teeth submitted to late replantation.
 ...
PMID:Microscopic investigation of the use of gallium nitrate for root surface treatment in rat teeth submitted to delayed replantation. 1817 9

Calcium hydroxide (CH) is the gold-standard intracanal dressing for teeth subjected to traumatic avulsion. A common complication after the replantation of avulsed teeth is root resorption (RR). The current review was conducted to compare the effect of CH with that of other intracanal medications and filling materials on inflammatory RR and replacement RR (ankylosis) in replanted teeth. The PubMed and Scopus databases were searched through June 2018 using specific keywords related to the title of the present article. The materials that were compared to CH were in 2 categories: 1) mineral trioxide aggregate (MTA) and endodontic sealers as permanent filling materials for single-visit treatment, and 2) Ledermix, bisphosphonates, acetazolamide, indomethacin, gallium nitrate, and enamel matrix-derived protein (Emdogain) as intracanal medicaments for multiple-visit management of avulsed teeth prior to the final obturation. MTA can be used as a single-visit root filling material; however, there are limited data on its efficacy due to a lack of clinical trials. Ledermix and acetazolamide were comparable to CH in reducing RR. Emdogain seems to be an interesting material, but the data supporting its use as an intracanal medication remain very limited. The conclusions drawn in this study were limited by the insufficiency of clinical trials.
 ...
PMID:Effect of calcium hydroxide on inflammatory root resorption and ankylosis in replanted teeth compared with other intracanal materials: a review. 3148 28