Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002986 (Fabry)
 5,646 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
X-linked 597
alpha-galactosidase A 526
Sep 407
alpha-galactosidase 395
Mol 209
Gal 185
GLA 179
X-linked recessive 101
ACS 52
MRI 52
vascular endothelium 51
hole 51
fused 38
endoplasmic reticulum 28
She 27
chronic renal failure 27
glucocerebrosidase 25
GAL 24
alpha-N-acetylgalactosaminidase 24
X-chromosome 20
ESX 20
lamp 20
CCD 19
MPS II 19
collagen 18
trip 18
GFR 17
glucosylceramide synthase 17
alpha-L-fucosidase 17
sky 15
glycoprotein 13
asymmetrical 13
sarcomeric 12
Alport syndrome 12
Pol 12
glucosidase 11
hemoglobin 11
axonal 11
membrane-bound 10
MPS VI 10
more...
Disease
Fabry 5646
proteinuria 180
stroke 170
lysosomal storage disease 149
renal disease 149
ventricular hypertrophy 146
renal failure 145
Gaucher disease 141
cardiomyopathy 125
angiokeratoma 111
hypertrophic cardiomyopathy 97
AMD 93
heart failure 69
cornea 68
hypohidrosis 68
neuropathy 68
hypertension 68
Niemann-Pick 58
chronic renal failure 50
amyloidosis 49
genetic disorder 46
acroparesthesia 45
Krabbe disease 45
enzyme deficiency 39
metabolic disorder 37
Tay-Sachs disease 35
metachromatic leukodystrophy 34
MPS I 34
fucosidosis 32
cold 31
renal insufficiency 31
mucopolysaccharidosis 30
glomerulosclerosis 26
diabetes 25
MPS II 25
peripheral neuropathy 25
myocardial infarction 24
Hurler 23
gangliosidosis 23
CCD 22
more...
Symptom
pain 217
abdominal pain 25
diarrhea 25
headache 16
paresthesia 15
dyspnea 14
weakness 14
tinnitus 12
vertigo 11
anesthesia 10
arthralgia 10
fatigue 10
vomiting 10
nausea 9
angina 9
dizziness 9
Gastrointestinal symptoms 8
syncope 8
collapse 7
chest pain 7
seizures 7
thinning 7
regurgitation 6
numbness 5
fever of unknown origin 5
ataxia 5
acute pain 4
hepatosplenomegaly 4
limb pain 4
rigors 4
Neuropathic pain 3
splenomegaly 3
exertional dyspnea 3
Wind 3
livedo 3
sleepiness 3
polyuria 3
myoclonus 3
Burning 2
cachexia 2
more...
Drug
Dermatol 63
Cardiovasc 43
ZnO 35
Fabrazyme 30
SiO2 13
Agalsidase alfa 11
TiO2 9
Nephron 8
Nephron 8
Cerezyme 7
Dial 7
Cerezyme 6
Orphan 5
nitroglycerin 4
CSF 4
Migalastat hydrochloride 3
lactose 3
SPP 3
ROC 3
Miglustat 3
SF6 3
lysine 3
Helium 2
Ceredase 2
Asn 2
Myozyme 2
Amiloride 2
Amiloride 2
Cordarone 2
Cordarone 2
vitamin E 2
NH3 2
TAT 2
Galactose 2
Rosiglitazone 1
DBS 1
Ambroxol hydrochloride 1
G418 1
Urso 1
NADH 1
more...
Enzyme
alpha-galactosidase 708
ACS 52
glucocerebrosidase 24
glucosylceramide synthase 17
alpha-N-acetylgalactosaminidase 16
beta-galactosidase 15
alpha-L-fucosidase 11
hexosaminidase 9
peroxidase 7
beta-glucosidase 7
alpha-glucosidase 7
beta-glucosidase 7
sulfatase 6
ceramide trihexosidase 6
alpha-L-fucosidase 6
renin 6
alpha-L-fucosidase 6
alpha-mannosidase 5
acid phosphatase 5
endonuclease 5
luciferase 4
superoxide dismutase 4
N-acetylgalactosaminidase 4
ERK 4
ACE 4
galactocerebrosidase 4
aspartylglucosaminidase 4
focal adhesion kinase 4
neuraminidase 4
beta-glucuronidase 4
PAM 4
pyruvate dehydrogenase 3
trypsin 3
pyruvate dehydrogenase 3
pyruvate dehydrogenase 3
SOI 3
AMP-activated protein kinase 2
P-glycoprotein 2
complex I 2
21-hydroxylase 2
more...
Compound
Dec 409
Clin 224
Gb3 224
silicon 222
GAL 200
water 106
DNA 89
silver 65
galactose 60
Cardiol 58
Letter 57
creatinine 56
ACS 52
ACS 52
oxygen 45
nitrogen 40
hydrogen 35
aluminum 34
phosphate 29
His 28
GM1 26
ethanol 25
copper 22
COS 21
iodine 19
methanol 18
glucose 17
boron 17
sodium 17
titanium 15
urea 15
arginine 14
SiO2 13
GM2 13
germanium 13
iron 13
glucose-6-phosphate 12
nitric oxide 11
calcium 11
zinc 11
more...