Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002986 (
Fabry
)
5,646
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Fabry disease
results in a global vasculopathy leading to early-onset stroke and renal and cardiac failure. We found that random
myeloperoxidase
in serum and plasma was significantly elevated in 73 consecutive male patients with
Fabry disease
. Random serum
myeloperoxidase
level in men predicted the risk of a
Fabry
vasculopathy-related event in subsequent years. Long-term enzyme replacement therapy did not reduce
myeloperoxidase
level or eliminate the risk of vasculopathic events.
...
PMID:Myeloperoxidase predicts risk of vasculopathic events in hemizgygous males with Fabry disease. 1715 17
