Gene/Protein
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Symptom
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Enzyme
Compound
Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0002986 (
Fabry
)
5,646
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Bouts of shooting pain along the extremities are common in the early stages of
Fabry's disease
. No pathological explanation has been advanced to clarify the mechanism of such pain. In the present case neuronal storage of glycolipid was confined to dorsal root ganglia neurones only. It is suggested that this may explain the shooting pain in
Fabry's disease
. In hereditary sensory radicular neuropathy, familial dysautonomia, and
tabes
dorsalis, changes in dorsal root ganglia cells cause similar clinical signs and thus it may be concluded that shooting pains in
Fabry's disease
may be caused by damage to dorsal root ganglia neurones.
...
PMID:Involvement of dorsal root ganglia in Fabry's disease. 641 95
