Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002962 (angina)
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Human Gene/Protein
TNFR1B 9.6
complement component 1, q subcomponent, A chain 9.6
FAM83C 9.6
Neutrophil protein 9.6
ZNF232 9.0
ADAMTS-14 9.0
UAP 8.7
SPPL2A 8.6
I3 protein 7.7
METS 7.7
MPS7 7.6
V5-6 7.6
CCS 7.5
Fetuin-B 7.2
Sur2 7.2
LILRB3 7.1
SK 1 7.1
LAD 7.1
V4-6 7.1
PRAX-1 7.0
EKV 7.0
TPRC 7.0
pancreatic stone protein 6.9
V1-3 6.8
APH-1B 6.7
LILRA1 6.7
LY9 6.7
HAST 6.7
NUS1 6.7
V2-6 6.7
CPN2 6.7
RITA 6.5
ARHGAP9 6.5
IQGAP1 protein 6.5
CMA1 6.4
ABHD2 6.4
CCTA 6.3
CA13 6.3
ADAMTS-2 6.3
Glycoprotein IIb 6.2
V1-2 6.1
NTG 6.0
BRX 6.0
P2RY1 6.0
Troponin T 5.9
IL4I1 5.9
LGALS2 5.9
granule membrane protein 140 5.9
KHK 5.9
NVL 5.8
RAO 5.8
deleted in liver cancer-1 5.8
TET1 5.8
CHD 5.8
AMN 5.7
FFR 5.7
TNG 5.6
Acid-sensing ion channel 3 5.6
CHOD 5.6
acetaldehyde dehydrogenase 2 5.6
C7 segment 5.6
PEPI 5.5
calcium channel 5.5
death receptor 3 5.5
CAD 5.5
Fibrinopeptide A 5.4
CXCL17 5.4
Coagulation factor V 5.4
KLKB1 5.3
HtrA2 5.3
CPK 5.3
LDLC 5.3
leupaxin 5.3
glycoprotein IIb 5.3
glutamate-ammonia ligase 5.3
PSMA6 5.3
DLST 5.3
PCI 5.3
Potassium channel 5.2
SAP 5.2
more...
Disease
Chronic adhesive pericarditis 10.6
Rapid atrial fibrillation 10.6
Q fever myocarditis 10.6
Anteroseptal infarction 10.6
staphylitis 10.6
Aortic Arch Syndrome 10.6
taboparalysis 10.6
Peripheral revascularisation 10.6
Single vessel coronary artery disease 10.6
Anginal attack 10.4
Refractory angina 10.3
Prinzmetal 10.3
Stable angina 9.8
chronic stable angina 9.7
Acute bronchospasm 9.6
Heberden's angina 9.6
Isolated aortic stenosis 9.6
Left ventricular hypokinesia 9.6
Tracheal calcification 9.6
new onset angina 9.5
vasospastic angina 9.5
Acute coronary insufficiency 9.3
Single vessel disease 9.1
coronary artery spasm 9.1
Increased oxygen demand 9.0
oropharyngeal neoplasm 9.0
Postoperative pulmonary edema 9.0
INVM 9.0
Salmonella paratyphi infection 9.0
Post-infarction ventricular septal defect 9.0
Segmental dysfunction 9.0
subacute ischemic heart disease 9.0
Double vessel disease 9.0
Postoperative myocardial infarction 8.9
Coronary artery stenosis 8.9
Non-Q wave myocardial infarction 8.8
Transient myocardial ischemia 8.7
unstable angina 8.7
Triple vessel disease 8.7
syndrome X 8.6
Q wave MI 8.6
Septic phlebitis 8.6
Myocardial bridging 8.6
Type IIb hyperlipidemia 8.6
Endocapillary GN 8.6
mesenteric vascular insufficiency 8.6
chest pain syndrome 8.5
subendocardial myocardial infarction 8.5
Transmural myocardial infarction 8.3
coronary insufficiency 8.3
Coronary atheroma 8.2
Generalized atherosclerosis 8.2
Severe sinus bradycardia 8.2
Post MI 8.2
Angina bullosa hemorrhagica 8.2
shoulder bursitis 8.2
Left main coronary artery disease 8.1
Isolated atrial amyloid 8.0
Hyperalphalipoproteinemia 8.0
alcohol related disorder 8.0
Single coronary artery 7.9
Coronary restenosis 7.9
Retinal migraine 7.7
von Willebrand disease type 3 7.7
sinus problem 7.7
cardiosclerosis 7.6
High output heart failure 7.6
rheumatic aortic stenosis 7.6
Left ventricular aneurysm 7.5
chronic ischemic heart disease 7.4
subclavian steal syndrome 7.4
Acquired generalized lipodystrophy 7.4
Complete left bundle branch block 7.2
Coronary artery ectasia 7.2
emotional outburst 7.2
allergic reaction to penicillin 7.2
total bilateral deafness 7.2
sympatheticotonia 7.2
anterolateral myocardial infarction 7.2
myocardial ischemia 7.2
more...
Symptom
angina 10.6
Chest pain at rest 10.6
Coronary spastic angina 10.6
Refractory angina pectoris 10.4
Nocturnal angina 10.2
Stable angina pectoris 10.1
Musculoskeletal tenderness 9.6
left carotid bruit 9.6
Sensation of warmth 9.6
exertional angina 9.4
Leg discomfort 9.0
Cardiac pain 8.9
cardialgia 8.9
ECG signs of myocardial ischemia 8.7
Ear symptoms 8.6
Diffuse spasm 8.6
atypical chest pain 8.3
exertional chest pain 8.3
musculoskeletal chest pain 8.1
precordial pain 7.9
SYMPTOMS 7.7
asynergy 7.6
Chest discomfort 7.6
Non-cardiac chest pain 7.5
spasm 7.4
chest pain 7.3
Kehr's sign 7.2
Cardiovascular symptoms 7.2
intestinal angina 7.1
cardiovascular disability 6.7
prickling sensation 6.7
Retrosternal pain 6.6
feeling dizzy 6.5
GI pain 6.3
Thoracic pain 6.2
Somatic pain 6.2
enanthema 5.9
Other pain 5.9
cold sweats 5.7
pedal edema 5.6
Stress symptoms 5.6
syncope 5.6
S3 gallop 5.5
Orthostasis 5.4
blushing 5.4
syncopal episodes 5.4
lightheadedness 5.3
presyncope 5.2
Pain at rest 5.2
ENT symptoms 5.1
peau d'orange 5.0
jaw pain 5.0
nocturnal polyuria 4.9
Amaurosis fugax 4.9
arm pain 4.9
giddiness 4.9
giddiness 4.9
Central pain 4.9
abnormal reflex 4.7
Visual symptoms 4.7
dyspnea 4.7
Spastic 4.7
exertional dyspnea 4.7
mouth pain 4.7
bigeminal 4.6
Cold intolerance 4.4
PAIN 4.4
dizziness 4.4
diastolic murmurs 4.4
leg edema 4.3
skin pain 4.3
orthopnea 4.3
shortness of breath 4.2
rales 4.0
feeling depressed 4.0
chest tightness 4.0
trigeminy 4.0
heartburn 4.0
respiratory problem 3.9
glossodynia 3.7
more...
Drug
Sigmart 9.6
Ranolazine 9.2
Ranolazine 9.2
Primacor 9.0
Besipirdine hydrochloride 9.0
Ildamen 9.0
Cibenzoline succinate 9.0
Perhexiline maleate 8.7
Lidoflazine 8.6
Pirsidomine 8.6
Myoscint 8.6
Petrin 8.6
CFPN-PI 8.6
Vascor 8.4
Perhexiline 8.4
Aggrastat 8.3
Metoprolol succinate 8.2
Primacor 8.2
Fostedil 8.2
Segontin 8.2
Molsidomine 8.1
Cardizem CD 7.9
Trandate 7.9
Tolamolol 7.7
Ergometrine 7.7
Ardeparin 7.7
Diltiazem hydrochloride 7.7
Deseril 7.7
Draflazine 7.6
Norvasc 7.5
nitroglycerin 7.4
Vascor 7.4
Tedisamil 7.3
Pentaerythritol tetranitrate 7.0
Trandate 6.9
Amlodipine besylate 6.9
Nadolol 6.9
Sarpogrelate hydrochloride 6.9
Arbutamine 6.9
Methergine 6.9
Hirulog 6.8
Visken 6.7
Fasudil hydrochloride 6.7
Sectral 6.7
Benidipine hydrochloride 6.7
Concor 6.7
Nipradilol 6.6
Isradipine 6.5
Halofenate 6.4
Inderal 6.4
Mexitil 6.4
Felodipine 6.3
Methergin 6.3
Lercanidipine 6.2
Abciximab 6.2
Mexitil 6.2
Fragmin 6.2
Dazoxiben 6.1
Isoptin 6.1
Atenolol 6.1
Regadenoson 6.0
Arachidonic Acid 5.9
Cardura 5.9
Alacepril 5.9
Calan 5.9
Cardura 5.9
Nicardipine hydrochloride 5.8
Lipitor 5.8
Tantum 5.7
Indoramin 5.7
Trandolapril 5.7
Prenylamine 5.7
Timolol 5.6
Zithromax 5.6
Trimepranol 5.6
Pentane 5.6
Acadesine 5.6
Fabrazyme 5.6
Dibenzyline 5.5
Minipress 5.5
more...
Enzyme
CCS 7.5
CAD 5.5
CAD 5.5
CAD 5.4
GP-I 4.7
creatine kinase 4.4
gamma-butyrobetaine hydroxylase 4.2
bromelin 3.8
ACE 3.8
LMT 3.8
SCS 3.4
KAT 3.4
protein disulfide-isomerase 3.2
tissue plasminogen activator 3.2
PAT 3.2
urokinase-type plasminogen activator 3.1
ACAT 3.1
prostacyclin synthase 3.0
pregnancy-associated plasma protein-A 2.8
PTA 2.8
CPN 2.8
ancrod 2.7
lactic acid dehydrogenase 2.7
2A protease 2.7
lactic acid dehydrogenase 2.7
cGMP phosphodiesterase 2.7
guanylate cyclase 2.6
thrombin-activatable fibrinolysis inhibitor 2.6
MCS 2.5
TMT 2.5
thromboxane synthase 2.4
ALDH 2.3
thrombin 2.2
aldehyde dehydrogenase 2.2
aldehyde dehydrogenase 2.2
paraoxonase 2.1
aldehyde dehydrogenase 2.1
SMP 2.1
phosphomannose isomerase 2.1
SST 2.0
lactic acid dehydrogenase 2.0
aldehyde dehydrogenase 1.9
PDE 1.9
renin 1.9
paraoxonase 1.8
PKG 1.8
MMP-3 1.8
tryptase 1.7
aldehyde dehydrogenase 1.7
3-hydroxy-3-methylglutaryl coenzyme A reductase 1.6
3C protease 1.6
cathepsin S 1.6
bromelain 1.6
methylenetetrahydrofolate reductase 1.5
thromboplastin 1.5
methylenetetrahydrofolate reductase 1.5
thiopurine methyltransferase 1.5
alpha-galactosidase 1.4
CDH 1.4
pyruvate dehydrogenase 1.4
pyruvate dehydrogenase 1.4
endothelin-converting enzyme 1.2
CPT 1.2
chymase 1.2
phosphodiesterase 1.2
PDH 1.1
AMP deaminase 1.1
phosphorylase 1.1
CYP3A4 1.1
gamma-glutamylcysteine synthetase 1.1
ceruloplasmin 1.1
glycerol kinase 1.0
plasmin 1.0
xanthine oxidase 1.0
AGT 1.0
acyl-CoA dehydrogenase 0.9
pyruvate dehydrogenase 0.9
lactate dehydrogenase 0.9
methionine synthase 0.9
PRA 0.9
more...
Compound
TTS 5 10.6
Epanolol 9.9
Ergonovine 8.9
4-fluorobenzamide 8.7
Pirbuterol hydrochloride 8.6
Dexpropranolol 8.2
Isosorbide mononitrate 8.1
Visnadine 8.0
AT-101 8.0
AT-101 7.9
AT-101 7.9
Nicorandil 7.9
Nitroglycerin 7.6
CCS 7.4
8,9-DiHETrE 7.4
D-Carnitine 7.4
Bepridil 7.3
Nisoldipine 7.3
Dipyridamole 7.3
Dipyridamole 7.3
Dipyridamole 7.3
Dipyridamole 7.3
Diltiazem 7.2
Diltiazem 7.2
Amlodipine 7.2
Gallopamil 7.0
Mibefradil 6.9
ISDN 6.9
Visnagin 6.9
Bisoprolol 6.7
3-pyridinecarboximidamide 6.7
N-(2-hydroxyethyl)nicotinamide 6.7
I-123 BMIPP 6.7
Labetalol 6.6
Tiapamil 6.6
Penbutolol 6.6
MB 1 6.6
Acebutolol 6.5
Nifedipine 6.5
Nicardipine 6.3
Metoprolol 6.3
Betaxolol 6.3
Metoprolol 6.3
Carteolol 6.2
Carvedilol 6.2
Mitox 6.1
Spartin 6.0
Pindolol 5.9
Fibrinopeptide A 5.8
Pirbuterol 5.8
DOTC 5.7
Ergot 5.7
Verapamil 5.7
Timolol 5.6
THP-ADM 5.6
Verapamil 5.6
Xamoterol 5.5
6-Keto-PGF1a 5.5
pentadecanoic acid 5.5
Ergotamine 5.5
AHA 5.5
Minipress 5.5
pentadecanoic acid 5.4
Dobutamine 5.4
PCI 5.4
Dibenzyline 5.4
Ergotamine tartrate 5.4
Ticlopidine 5.4
Esmolol 5.3
Sulfinpyrazone 5.3
Methylxanthine 5.2
Quinapril 5.1
Tirofiban 5.1
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 5.1
2,3-dinor-thromboxane 5.0
Propranolol 4.9
Prenalterol 4.9
Propranolol 4.8
14,15-DHET 4.8
Thromboxane B2 4.8
more...