Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002962 (angina)
21,142 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1383
calcium channel 476
Mal 367
insulin 253
C-reactive protein 235
fibrinogen 197
HDL 192
She 188
creatine kinase 179
LAD 147
Pol 140
CAD 130
Mol 112
ACE 109
thrombin 107
CHD 97
ATP 90
renin 87
beta 1 85
collagen 82
ADP 77
CCS 71
CRP 71
hemoglobin 66
PLA 64
urokinase-type plasminogen activator 62
cytokine 56
reserved 54
natriuretic peptide 54
PCI 54
Lp(a) 51
Men 50
bradykinin 49
GPIIb 49
chronic renal failure 49
CPK 47
angiotensin II 47
glycoprotein IIb 47
albumin 46
ACS 46
endothelin-1 45
myoglobin 45
P-selectin 44
troponin I 43
JAMA 43
cardiac muscle 43
troponin T 43
MRI 43
prothrombin 42
LDL receptor 42
beta-thromboglobulin 41
interleukin-6 41
tumor necrosis factor 40
vascular endothelial growth factor 38
IL-6 37
SAP 37
plasminogen activator inhibitor-1 37
nodal 35
ACC 35
platelet factor 4 35
cardiac troponin I 35
Cor 34
apolipoprotein 34
superoxide dismutase 34
tissue plasminogen activator 33
vasopressin 33
vascular endothelium 32
plasminogen 32
glycoprotein 32
plasminogen activator inhibitor 31
Gen 30
von Willebrand factor 29
phosphodiesterase 28
antithrombin III 28
SBP 28
guanylate cyclase 28
apolipoprotein B 27
tissue factor 27
UAP 26
lactate dehydrogenase 26
more...
Disease
myocardial infarction 5617
coronary artery disease 4080
myocardial ischemia 2980
hypertension 2330
acute myocardial infarction 2128
depression 2079
ischemia 2065
unstable angina 1781
heart failure 1539
coronary heart disease 1342
diabetes 1337
atherosclerosis 1140
stroke 1029
congestive heart failure 947
cardiovascular disease 599
plaque 567
chronic stable angina 405
coronary artery spasm 398
heart disease 387
vasospastic angina 373
obesity 272
cardiomyopathy 249
aortic stenosis 248
hypercholesterolemia 241
ventricular hypertrophy 240
ventricular fibrillation 218
hyperlipidemia 207
syndrome X 196
cold 185
asthma 180
cancer 179
Prinzmetal 178
peripheral vascular disease 174
hypertrophic cardiomyopathy 167
mitral regurgitation 165
coronary insufficiency 163
coronary occlusion 161
LAD 147
brucellosis 141
essential hypertension 137
left ventricular failure 133
type 2 diabetes 126
intermittent claudication 126
vascular disease 121
aortic regurgitation 119
tumor 118
renal disease 117
dyslipidemia 113
atrioventricular block 108
chronic obstructive pulmonary disease 108
SEM 103
renal failure 100
arteriosclerosis 100
migraine 100
transient ischemic attack 99
pulmonary hypertension 99
pulmonary edema 91
dilated cardiomyopathy 87
chronic ischemic heart disease 75
anterior myocardial infarction 74
sympathomimetic 73
left bundle branch block 73
valvular heart disease 73
claudication 71
anemia 69
coronary thrombosis 69
chronic renal failure 67
ischemic cardiomyopathy 66
inferior myocardial infarction 66
cerebral infarction 65
myocarditis 62
systemic lupus erythematosus 60
gastroesophageal reflux disease 60
hyperthyroidism 59
pericarditis 59
metabolic syndrome 57
mitral valve prolapse 56
Takayasu 55
endocarditis 54
vasculitis 53
more...
Symptom
angina 21142
chest pain 1796
pain 1247
spasm 817
dyspnea 495
exertional angina 337
syncope 293
headache 272
fatigue 193
anesthesia 165
discomfort 145
discomfort 143
dizziness 140
atypical chest pain 134
nausea 85
asynergy 82
shortness of breath 65
regurgitation 59
exertional dyspnea 57
abdominal pain 57
flushing 54
overweight 52
weakness 44
vomiting 42
diarrhea 37
exhaustion 34
analgesia 34
constipation 34
exertional chest pain 33
collapse 33
hypothermia 32
cough 30
precordial pain 28
vertigo 26
seizures 24
back pain 23
tremor 22
heartburn 22
functional recovery 20
snoring 20
asthenia 17
cardialgia 16
Ill 16
nausea and vomiting 15
presyncope 15
paresthesia 14
syncopal episodes 14
insomnia 14
erythema 13
Stable angina pectoris 13
respiratory distress 13
lightheadedness 13
sleepiness 12
anorexia 12
arthralgia 12
myalgia 12
cyanosis 12
thinning 11
hemoptysis 10
arm pain 10
epigastric pain 10
numbness 9
leg edema 9
Refractory angina pectoris 9
dystonia 9
chills 9
lethargy 9
low back pain 9
chest tightness 8
wheezing 8
tinnitus 8
hemiplegia 7
pedal edema 7
rales 7
acute pain 7
leg pain 7
hepatomegaly 6
skin irritation 6
agitation 6
orthopnea 6
more...
Drug
Cardiovasc 1654
nitroglycerin 1028
Monit 121
Ranolazine 98
Ranolazine 98
Atenolol 39
vitamin E 33
Molsidomine 28
Coral 26
Clopidogrel 24
ascorbate 21
ROC 20
Felodipine 20
Captopril 16
Dial 15
Isradipine 15
Abciximab 15
Timolol 14
Dermatol 14
Nadolol 13
Perhexiline 13
Isoptin 12
lysine 11
Lidoflazine 11
IL-2 11
caffeine 10
Inderal 10
Aggrastat 9
Vitamin E 9
AGG 9
Digitalis 9
Fragmin 9
Nephron 9
Streptokinase 9
Bayer 8
Ergometrine 8
ICI 8
Cardizem CD 8
Simvastatin 7
Angiotensin II 7
Nebivolol 7
Perhexiline maleate 7
Ginseng 7
Diltiazem hydrochloride 7
Viagra 6
niacin 6
Atropine 6
Phentolamine 6
Bezafibrate 6
G-CSF 5
ampicillin 5
Clonidine 5
Amlodipine besylate 5
ADM 5
Bivalirudin 5
Norvasc 5
Asthma 5
Leaf 5
EPI 5
NADH 5
lactose 5
Dalteparin 4
Viagra 4
Nitric Oxide 4
Sodium nitroprusside 4
CPR 4
Iloprost 4
IFN-gamma 4
Pravastatin 4
ROS 4
Trandolapril 4
ENT 4
EPA 4
CSF 4
Ramipril 4
Diurnal 4
CVA 4
Dazoxiben 4
uPA 4
Indomethacin 4
more...
Enzyme
creatine kinase 257
ACE 166
CAD 130
CAD 130
CAD 130
thrombin 104
renin 87
CCS 71
tissue plasminogen activator 69
urokinase-type plasminogen activator 61
ACS 46
superoxide dismutase 39
lactate dehydrogenase 37
guanylate cyclase 35
phosphodiesterase 28
thromboplastin 25
peroxidase 22
aspartate aminotransferase 20
ERK 19
APC 19
mitogen-activated protein kinase 18
ATPase 16
catalase 15
aldehyde dehydrogenase 14
glutathione peroxidase 14
aldehyde dehydrogenase 13
alanine aminotransferase 13
aldehyde dehydrogenase 13
aldehyde dehydrogenase 13
aldehyde dehydrogenase 13
plasmin 12
alkaline phosphatase 12
protein kinase C 12
phospholipase A2 11
NO synthase 11
xanthine oxidase 11
protein kinase 11
PDE 9
CYP3A4 9
PTA 8
phosphorylase 8
P-glycoprotein 8
MMP-3 8
collagenase 8
trypsin 8
caspase-3 7
pyruvate dehydrogenase 7
ceruloplasmin 7
SCS 7
gamma-glutamyl transpeptidase 7
CPT 7
AST 7
tryptase 6
NADPH oxidase 6
pyruvate dehydrogenase 6
KAT 6
monoamine oxidase 6
focal adhesion kinase 6
kallikrein 6
PKG 6
pyruvate dehydrogenase 6
acetylcholinesterase 5
AMP-activated protein kinase 5
paraoxonase 5
paraoxonase 5
elastase 5
PAT 5
glutathione S-transferase 4
NADPH oxidase 4
CPR 4
MMP 4
methylenetetrahydrofolate reductase 4
cGMP phosphodiesterase 4
succinate dehydrogenase 4
adenylate cyclase 4
methylenetetrahydrofolate reductase 4
nitrate reductase 3
nitrate reductase 3
TMT 3
heme oxygenase 3
more...
Compound
Cardiol 4073
Dec 1520
Clin 1430
calcium 1267
oxygen 1089
nitrate 452
glucose 328
nitric oxide 201
Nifedipine 176
sodium 172
acetate 145
potassium 143
Nitroglycerin 131
Verapamil 128
His 127
Diltiazem 126
Diltiazem 126
creatinine 125
Dipyridamole 116
Dipyridamole 116
Dipyridamole 116
Dipyridamole 116
Verapamil 114
ADP 103
prostacyclin 99
ATP 91
Propranolol 84
water 84
ASA 81
CO2 80
ADP 78
Propranolol 77
ADP 77
CCS 71
Nicorandil 67
noradrenaline 63
Amlodipine 62
ISDN 62
PCI 54
arginine 51
phosphate 50
cGMP 49
ACS 46
ACS 46
AHA 45
Optimal 45
aldosterone 45
Ergonovine 45
Metoprolol 44
homocysteine 42
DNA 41
Heparin 40
Metoprolol 39
Adenosine 39
ethanol 38
iodine 36
Carvedilol 35
Nitrate 35
Cholesterol 34
Nicardipine 33
sulfate 33
salt 31
Off 31
iron 29
nitrogen 28
L-carnitine 27
Amiodarone 27
Insulin 27
cAMP 27
Dobutamine 26
glutamate 26
Nisoldipine 26
Labetalol 26
Fibrinogen 23
GMP 23
AT-101 22
Bepridil 22
alanine 22
Thyroid 22
AT-101 22
more...