Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002962 (angina)
 21,142 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1383
calcium channel 476
Mal 367
insulin 253
C-reactive protein 235
fibrinogen 197
HDL 192
She 188
creatine kinase 179
LAD 147
Pol 140
CAD 130
Mol 112
ACE 109
thrombin 107
CHD 97
ATP 90
renin 87
beta 1 85
collagen 82
ADP 77
CRP 71
CCS 71
hemoglobin 66
PLA 64
urokinase-type plasminogen activator 62
cytokine 56
PCI 54
natriuretic peptide 54
reserved 54
Lp(a) 51
Men 50
GPIIb 49
bradykinin 49
chronic renal failure 49
angiotensin II 47
glycoprotein IIb 47
CPK 47
ACS 46
albumin 46
endothelin-1 45
myoglobin 45
P-selectin 44
troponin I 43
MRI 43
cardiac muscle 43
JAMA 43
troponin T 43
LDL receptor 42
prothrombin 42
interleukin-6 41
beta-thromboglobulin 41
tumor necrosis factor 40
vascular endothelial growth factor 38
SAP 37
plasminogen activator inhibitor-1 37
IL-6 37
platelet factor 4 35
nodal 35
ACC 35
cardiac troponin I 35
Cor 34
apolipoprotein 34
superoxide dismutase 34
vasopressin 33
tissue plasminogen activator 33
plasminogen 32
vascular endothelium 32
glycoprotein 32
plasminogen activator inhibitor 31
Gen 30
von Willebrand factor 29
phosphodiesterase 28
guanylate cyclase 28
antithrombin III 28
SBP 28
apolipoprotein B 27
tissue factor 27
lactate dehydrogenase 26
UAP 26
beta-endorphin 25
ICD 25
endothelial nitric oxide synthase 25
apoE 24
thromboplastin 23
CO2 23
NTG 23
LDH 23
nitric oxide synthase 23
CAS 22
Rho 22
thyroid hormone 22
TET1 22
TNF 20
IL-8 20
METS 20
Angiotensin-converting enzyme 20
E-selectin 20
antithrombin 19
DBP 19
AMN 19
IgA 19
cardiac troponin T 19
intercellular adhesion molecule-1 19
atrial natriuretic peptide 19
GSH 19
erythropoietin 19
Nei 19
PEP 19
COPD 18
angiotensin II receptor 18
adiponectin 18
IL-10 18
NIDDM 18
pancreatic stone protein 17
BNP 17
serum albumin 17
adhesion molecule 17
TNF-alpha 17
membrane-bound 16
substance P 16
protein C 16
vascular cell adhesion molecule-1 16
Troponin T 16
myosin 16
Xin 16
mast cell 16
ET-1 15
San 15
Ang II 15
proton pump 15
HDL2 15
A-I 15
VIP 15
5-hydroxytryptamine 15
factor VII 14
VEGF 14
ATPase 14
glucagon 14
CD4 14
polypeptide 14
glutathione peroxidase 14
cytochrome P450 14
catalase 14
CD40 ligand 14
ANOVA 14
HMG-CoA reductase 14
adenosine receptor 13
aldehyde dehydrogenase 13
matrix metalloproteinase 13
angiotensin receptor 13
parathyroid hormone 13
P2Y12 12
Hop 12
AMP 12
xanthine oxidase 12
EST) 12
L-type calcium channel 12
CD62P 12
sodium channel 12
more...
Disease
myocardial infarction 5617
coronary artery disease 4080
myocardial ischemia 2980
hypertension 2330
acute myocardial infarction 2128
depression 2079
ischemia 2065
unstable angina 1781
heart failure 1539
coronary heart disease 1342
diabetes 1337
atherosclerosis 1140
stroke 1029
congestive heart failure 947
cardiovascular disease 599
plaque 567
chronic stable angina 405
coronary artery spasm 398
heart disease 387
vasospastic angina 373
obesity 272
cardiomyopathy 249
aortic stenosis 248
hypercholesterolemia 241
ventricular hypertrophy 240
ventricular fibrillation 218
hyperlipidemia 207
syndrome X 196
cold 185
asthma 180
cancer 179
Prinzmetal 178
peripheral vascular disease 174
hypertrophic cardiomyopathy 167
mitral regurgitation 165
coronary insufficiency 163
coronary occlusion 161
LAD 147
brucellosis 141
essential hypertension 137
left ventricular failure 133
type 2 diabetes 126
intermittent claudication 126
vascular disease 121
aortic regurgitation 119
tumor 118
renal disease 117
dyslipidemia 113
atrioventricular block 108
chronic obstructive pulmonary disease 108
SEM 103
arteriosclerosis 100
migraine 100
renal failure 100
pulmonary hypertension 99
transient ischemic attack 99
pulmonary edema 91
dilated cardiomyopathy 87
chronic ischemic heart disease 75
anterior myocardial infarction 74
left bundle branch block 73
valvular heart disease 73
sympathomimetic 73
claudication 71
anemia 69
coronary thrombosis 69
chronic renal failure 67
ischemic cardiomyopathy 66
inferior myocardial infarction 66
cerebral infarction 65
myocarditis 62
gastroesophageal reflux disease 60
systemic lupus erythematosus 60
hyperthyroidism 59
pericarditis 59
metabolic syndrome 57
mitral valve prolapse 56
Takayasu 55
endocarditis 54
vasculitis 53
arthritis 53
pneumonia 53
psychological stress 51
erectile dysfunction 51
heart block 49
cardiosclerosis 49
STEMI 48
hypothyroidism 47
pulmonary embolism 47
akinesia 46
ventricular septal defect 45
thrombocytopenia 43
proteinuria 42
emotional stress 42
abdominal aortic aneurysm 42
glucose intolerance 42
subclavian steal syndrome 42
coronary artery aneurysm 40
renal insufficiency 40
West 40
chronic pain 39
aortitis 37
sepsis 37
lung cancer 37
Kawasaki disease 37
cerebral ischemia 36
hyperlipoproteinemia 36
right bundle branch block 36
flutter 36
Raynaud's phenomenon 36
hypertensive heart disease 36
rheumatoid arthritis 36
Esophageal 35
mitral stenosis 34
systolic hypertension 34
Plaque 34
amyloidosis 33
thyrotoxicosis 33
celiac disease 33
retinopathy 33
chest pain syndrome 33
sinus tachycardia 32
rash 32
supraventricular tachycardia 32
dyskinesia 32
breast cancer 31
Endothelial dysfunction 31
cardiovascular risk factor 31
bronchitis 31
osteoporosis 30
lupus 30
aggression 30
dementia 29
bronchitis 29
carcinoma 29
chronic bronchitis 29
sepsis 29
hyperinsulinemia 28
hyperglycemia 28
aortic aneurysm 28
deep vein thrombosis 27
bronchospasm 27
pheochromocytoma 27
cirrhosis 27
epilepsy 27
pericardial effusion 27
Acute coronary syndrome 27
Raynaud 27
neuropathy 26
Myocardial bridging 26
neuroticism 26
Chlamydia 26
diabetic nephropathy 25
glaucoma 25
Syndrome 25
obstructive sleep apnea 25
idiopathic thrombocytopenic purpura 25
ICD 25
ventricular dilatation 24
Hypertrophic cardiomyopathy 24
more...
Symptom
angina 21142
chest pain 1796
pain 1247
spasm 817
dyspnea 495
exertional angina 337
syncope 293
headache 272
fatigue 193
anesthesia 165
discomfort 145
discomfort 143
dizziness 140
atypical chest pain 134
nausea 85
asynergy 82
shortness of breath 65
regurgitation 59
exertional dyspnea 57
abdominal pain 57
flushing 54
overweight 52
weakness 44
vomiting 42
diarrhea 37
exhaustion 34
analgesia 34
constipation 34
exertional chest pain 33
collapse 33
hypothermia 32
cough 30
precordial pain 28
vertigo 26
seizures 24
back pain 23
heartburn 22
tremor 22
snoring 20
functional recovery 20
asthenia 17
cardialgia 16
Ill 16
nausea and vomiting 15
presyncope 15
paresthesia 14
syncopal episodes 14
insomnia 14
lightheadedness 13
erythema 13
Stable angina pectoris 13
respiratory distress 13
cyanosis 12
sleepiness 12
myalgia 12
arthralgia 12
anorexia 12
thinning 11
hemoptysis 10
arm pain 10
epigastric pain 10
Refractory angina pectoris 9
dystonia 9
leg edema 9
lethargy 9
low back pain 9
chills 9
numbness 9
tinnitus 8
wheezing 8
chest tightness 8
pedal edema 7
hemiplegia 7
leg pain 7
acute pain 7
rales 7
intestinal angina 6
splenomegaly 6
hepatomegaly 6
colic 6
skin irritation 6
orthopnea 6
pallor 6
agitation 6
neck pain 6
livedo 5
acute abdomen 5
hepatosplenomegaly 5
blushing 5
ECG signs of myocardial ischemia 5
facial pain 5
Cardiac pain 5
spasticity 5
limb pain 5
sore throat 5
ENT 4
dental pain 4
hoarseness 4
Nocturnal angina 4
jaw pain 4
CSR 4
dysuria 4
cachexia 4
hypertonia 4
hypotonia 4
Cardiovascular symptoms 4
Decreased activity 4
oliguria 4
paresis 4
giddiness 4
giddiness 4
blurred vision 4
sinus pressure 3
nocturnal polyuria 3
acidity 3
hypercapnia 3
hypoproteinemia 3
incoordination 3
Spastic 3
muscle cramps 3
nasal congestion 3
neuralgia 3
stomach pain 3
chronic cough 3
tingling 3
intestinal bleeding 3
musculoskeletal chest pain 3
shoulder pain 3
distraction 2
Coronary spastic angina 2
peau d'orange 2
starvation 2
acute stress 2
SYMPTOMS 2
productive cough 2
tonic-clonic seizure 2
acute abdominal pain 2
dysarthria 2
hunger 2
Visual symptoms 2
Pain at rest 2
cancer pain 2
muscle stiffness 2
chorea 2
otalgia 2
alexithymia 2
belching 2
chronic back pain 2
HSA 2
eds 2
bigeminal 2
excessive sweating 2
left carotid bruit 2
fever of unknown origin 2
Chest discomfort 2
forgetfulness 2
Depressive symptoms 2
night sweats 2
hot flushes 2
Non-cardiac chest pain 2
more...
Drug
Cardiovasc 1654
nitroglycerin 1028
Monit 121
Ranolazine 98
Ranolazine 98
Atenolol 39
vitamin E 33
Molsidomine 28
Coral 26
Clopidogrel 24
ascorbate 21
Felodipine 20
ROC 20
Captopril 16
Isradipine 15
Abciximab 15
Dial 15
Timolol 14
Dermatol 14
Nadolol 13
Perhexiline 13
Isoptin 12
lysine 11
Lidoflazine 11
IL-2 11
caffeine 10
Inderal 10
Aggrastat 9
Fragmin 9
Nephron 9
Digitalis 9
Vitamin E 9
Streptokinase 9
AGG 9
Bayer 8
Cardizem CD 8
Ergometrine 8
ICI 8
Ginseng 7
Perhexiline maleate 7
Nebivolol 7
Angiotensin II 7
Simvastatin 7
Diltiazem hydrochloride 7
Phentolamine 6
Viagra 6
Bezafibrate 6
niacin 6
Atropine 6
Asthma 5
Clonidine 5
Amlodipine besylate 5
Norvasc 5
G-CSF 5
ADM 5
ampicillin 5
NADH 5
Bivalirudin 5
Leaf 5
EPI 5
lactose 5
Nitric Oxide 4
Dalteparin 4
Iloprost 4
Pravastatin 4
CPR 4
Viagra 4
CSF 4
uPA 4
Tedisamil 4
IFN-gamma 4
Sodium nitroprusside 4
Indomethacin 4
ROS 4
CVA 4
Diurnal 4
Ramipril 4
Nephron 4
Trandolapril 4
Dazoxiben 4
EPA 4
ENT 4
Hirulog 4
Nipradilol 4
CaCl2 3
Bromelain 3
Phenytoin 3
Spectrum 3
Lercanidipine 3
Clofibrate 3
Trapidil 3
Enoximone 3
Urokinase 3
Methergin 3
Lipitor 3
PTH 3
CTA 3
CaCl2 3
Cimetidine 3
Ringer's solution 3
CaCl2 3
Cimetidine 3
ABC 3
Visken 3
Metoprolol succinate 3
Vascor 3
PCP 3
Histamine 3
Bevacizumab 3
Calan 3
Lipitor 3
Lipitor 3
Estrogens 2
Enalaprilat 2
Trandate 2
Timolol maleate 2
Serum albumin 2
TAT 2
Glycerol 2
Tocilizumab 2
Propofol 2
Iopamidol 2
Ethanol 2
Fraction 2
EDR 2
Optison 2
Eptifibatide 2
Perindopril 2
Pentane 2
Lovastatin 2
SMP 2
Trandate 2
TAC 2
PTC 2
LMWH 2
Alprenolol 2
DNase I 2
ACT 2
Iohexol 2
Adenosine triphosphate 2
Rituximab 2
ADR 2
Deseril 2
MgSO4 2
Regadenoson 2
Check 2
Segontin 2
Plavix 2
Photofrin 2
DHT 2
Pentaerythritol tetranitrate 2
Bupivacaine 2
Ancrod 2
Tolamolol 2
Enalaprilat 2
Doxycycline 2
Antithrombin III 2
Buscopan 2
Scopolamine 2
Triclosan 2
more...
Enzyme
creatine kinase 257
ACE 166
CAD 130
CAD 130
CAD 130
thrombin 104
renin 87
CCS 71
tissue plasminogen activator 69
urokinase-type plasminogen activator 61
ACS 46
superoxide dismutase 39
lactate dehydrogenase 37
guanylate cyclase 35
phosphodiesterase 28
thromboplastin 25
peroxidase 22
aspartate aminotransferase 20
APC 19
ERK 19
mitogen-activated protein kinase 18
ATPase 16
catalase 15
glutathione peroxidase 14
aldehyde dehydrogenase 14
aldehyde dehydrogenase 13
aldehyde dehydrogenase 13
alanine aminotransferase 13
aldehyde dehydrogenase 13
aldehyde dehydrogenase 13
protein kinase C 12
plasmin 12
alkaline phosphatase 12
NO synthase 11
phospholipase A2 11
protein kinase 11
xanthine oxidase 11
CYP3A4 9
PDE 9
P-glycoprotein 8
trypsin 8
phosphorylase 8
PTA 8
collagenase 8
MMP-3 8
caspase-3 7
CPT 7
pyruvate dehydrogenase 7
AST 7
SCS 7
gamma-glutamyl transpeptidase 7
ceruloplasmin 7
tryptase 6
PKG 6
pyruvate dehydrogenase 6
monoamine oxidase 6
focal adhesion kinase 6
kallikrein 6
KAT 6
NADPH oxidase 6
pyruvate dehydrogenase 6
paraoxonase 5
paraoxonase 5
PAT 5
acetylcholinesterase 5
elastase 5
AMP-activated protein kinase 5
methylenetetrahydrofolate reductase 4
adenylate cyclase 4
CPR 4
succinate dehydrogenase 4
cGMP phosphodiesterase 4
MMP 4
methylenetetrahydrofolate reductase 4
NADPH oxidase 4
glutathione S-transferase 4
NOS 3
luciferase 3
PCP 3
alpha-galactosidase 3
proteasome 3
nitrate reductase 3
calcineurin 3
CPT 3
MCS 3
ALDH 3
adenosine deaminase 3
lipase 3
adenosine deaminase 3
glutathione reductase 3
3-hydroxy-3-methylglutaryl coenzyme A reductase 3
TMT 3
nitrate reductase 3
nitrate reductase 3
nitrate reductase 3
nitrate reductase 3
nitrate reductase 3
reverse transcriptase 3
CPT 3
heme oxygenase 3
5'-nucleotidase 2
DNA polymerase 2
AMPK 2
caspase-9 2
lipoxygenase 2
RNase 2
cholesterol acyltransferase 2
RNase 2
gamma-glutamylcysteine synthetase 2
ACAT 2
lysozyme 2
MEK 2
lactic acid dehydrogenase 2
MAP 2
phosphofructokinase 2
prostacyclin synthase 2
arginase 2
endonuclease 2
cytochrome oxidase 2
DNase 2
lactic acid dehydrogenase 2
matrix metalloproteinase 9 2
thromboxane synthase 2
lactic acid dehydrogenase 2
TAT 2
SST 2
sulfatase 2
matrix metalloproteinase 2 2
CD10 2
AOR 2
AMPK 2
neutrophil elastase 2
SMP 2
thyroid peroxidase 2
bromelain 2
chymase 2
transcriptase 2
cholinesterase 2
CPN 2
PRA 2
RNA polymerase 2
GSK 1
PAL 1
LMT 1
BIS 1
apyrase 1
PAL 1
GP-I 1
methionine synthase 1
glycerol kinase 1
methionine synthase 1
gamma-butyrobetaine hydroxylase 1
lecithin:cholesterol acyltransferase 1
p100 1
alpha-glucosidase 1
histidine kinase 1
beta-glucuronidase 1
PDH 1
dopamine beta-hydroxylase 1
ancrod 1
more...
Compound
Cardiol 4073
Dec 1520
Clin 1430
calcium 1267
oxygen 1089
nitrate 452
glucose 328
nitric oxide 201
Nifedipine 176
sodium 172
acetate 145
potassium 143
Nitroglycerin 131
Verapamil 128
His 127
Diltiazem 126
Diltiazem 126
creatinine 125
Dipyridamole 116
Dipyridamole 116
Dipyridamole 116
Dipyridamole 116
Verapamil 114
ADP 103
prostacyclin 99
ATP 91
Propranolol 84
water 84
ASA 81
CO2 80
ADP 78
Propranolol 77
ADP 77
CCS 71
Nicorandil 67
noradrenaline 63
ISDN 62
Amlodipine 62
PCI 54
arginine 51
phosphate 50
cGMP 49
ACS 46
ACS 46
AHA 45
aldosterone 45
Ergonovine 45
Optimal 45
Metoprolol 44
homocysteine 42
DNA 41
Heparin 40
Metoprolol 39
Adenosine 39
ethanol 38
iodine 36
Nitrate 35
Carvedilol 35
Cholesterol 34
Nicardipine 33
sulfate 33
Off 31
salt 31
iron 29
nitrogen 28
Amiodarone 27
cAMP 27
L-carnitine 27
Insulin 27
Dobutamine 26
glutamate 26
Labetalol 26
Nisoldipine 26
Fibrinogen 23
GMP 23
Bepridil 22
AT-101 22
alanine 22
Thyroid 22
AT-101 22
AT-101 22
ACh 21
5-HT 20
glycerol 20
TNF 20
MDA 19
DBP 19
GSH 19
Lactate 19
DBP 19
PEP 19
GSH 19
ammonia 19
urea 18
Angiotensin II 18
TXA2 18
hydrogen 17
6-12 17
rubidium 17
BNP 17
Warfarin 17
Dial 16
A 42 16
Estrogen 16
piperazine 16
Pindolol 15
5-FU 15
nicotinamide 15
Timolol 14
Bisoprolol 14
A 71 14
Atorvastatin 14
TSH 14
Mibefradil 14
aldehyde 13
nicotinic acid 13
Adrenal 13
Thromboxane 13
methionine 13
pentaerythritol 13
prostaglandin E1 13
TCM 12
nicotinic acid 12
copper 12
nicotinic acid 12
TTS 12
Isoproterenol 12
pentadecanoic acid 12
nicotinic acid 12
lysine 12
AMP 12
pentadecanoic acid 12
TCM 12
bromide 12
Estrogen 11
DDD 11
Epanolol 11
cysteine 11
N-acetylcysteine 11
Digoxin 11
galactose 10
Acebutolol 10
Vitamin E 10
Ticlopidine 10
methanol 10
HCl 10
Sildenafil 10
PEG 10
coenzyme Q10 10
Testosterone 10
caffeine 10
CPB 9
IPN 9
neopterin 9
barium 9
acetonitrile 9
leucine 9
Ergot 9
Testosterone 9
aluminum 9
more...