Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002962 (angina)
 21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Altogether 29 patients (14 with a characteristic clinical picture of CHD, 6 with probable angina and 9 with nonischemic cardialgia) were investigated by methods of two-dimensional echocardiography (echoCG) at rest and in combination with isometric exercise and left atrial transesophageal pacing test (LATPT) as well as by electrocardiographic exercise tests (bicycle ergometry testing and LATPT). EchCG exercise tests were conducted in most of the examinees (96.6%) whereas bicycle ergometry results were obtained in 75.9% of the patients (p less than 0.05). A significantly higher frequency of positive results of echoCG exercise tests in patients with typical CHD as compared to electrocardiographic exercise tests, and significantly high correlation of the results of the combination of echoCG with isometric exercise and echoCG with a degree of the pain syndrome in the heart area were revealed. The results obtained made it possible to recommend echoCG exercise tests for the diagnosis of coronary insufficiency.
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PMID:[Comparative assessment of stress electrocardiographic and echocardiographic tests in the diagnosis of insufficiency of the coronary circulation]. 321 90

A total of 168 patients admitted to the intensive care department with the diagnosis of unstable angina pectoris (UA), were investigated. Proceeding from the clinical criteria, the patients were divided into 2 groups: with primary (the 1st group) and progressive (the 2nd group) angina. The diagnosis was confirmed by the transesophageal pacing test (TEPT) performed in parallel with two-dimensional echocardiography. Positive TEPT was noted in 84% of the patients in the 2nd group and in 39% of the patients in the 1st group. The volume and expression of ischemia at the height of stimulation (ECTG findings) did not differ in both groups. Some patients with negative TEPT (in both groups) demonstrated an unfavorable time course of volumetric indices: an increase in end systolic and end diastolic volumes, a decrease in the ejection fraction. However, the diagnosis of CHD could not be excluded. Patients need further examination.
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PMID:[Coronary reserve and myocardial function in unstable stenocardia]. 324 42

A WHO standard questionnaire for the detection of angina pectoris was used in examination of 6914 males aged 40 to 59. The character of the pain syndrome was correlated with risk factor (RF) levels, the prevalence of ECG-signs of ischemic changes, the incidence of cases of myocardial infarction (MI) during a 5-year follow-up period. Examinees with angina pectoris had the highest levels of systolic and diastolic AP, cholesterol, body mass, the highest frequency of lethal and nonlethal MI. Examinees with chest pains resulting from physical exercise but atypical of angina had higher levels of the main RF and ECG-signs of ischemic changes and higher rates (2-fold) of new cases of MI and its mortality as compared to persons without chest pains or with pains unrelated with physical exercise during a 5-year prospective study. This evidence suggests a necessity of a more detailed investigation of the latter group to reach the entire group of CHD patients.
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PMID:[Chest pains detected on the basis of the WHO standard questionnaire and their prognostic significance]. 342 84

The paper is concerned with an analysis of the results of ECG daily monitoring in 60 CHD patients: 32 of them had a progressive form of unstable angina pectoris (the 1st group), and 28--stable angina pectoris (the 2nd group). Significant differences were revealed in the study groups with regard to the frequency of detection of disturbed rhythm, the total number of extrasystoles during a day, and a degree of their gradation.
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PMID:[Comparative analysis of the results of daily ECG monitoring of patients with progressive and stable stenocardia]. 342 85

Two-dimensional echocardiography was used to study the state of the proximal part of the left coronary artery (LCA) in 106 males: 39 patients after anterior myocardial infarction, 28--after posteroinferior myocardial infarction, 11 patients with angina pectoris without infarction, and 28 healthy persons. The comparison of the results of coronary radiography and echocardiography in 21 patients showed that the sensitivity and specificity of echocardiography in the diagnosis of stenosis of the left main coronary artery was 80 and 100%, respectively. Methods of assessment of echographic density of the LCA walls on the basis of comparison of their density with echographic density of the walls of the aorta and aortic valve showed that in the CHD patients LCA wall density was increased as compared to that of the healthy persons, and in the patients after anterio myocardial infarction it was increased as compared to that of the healthy persons and other CHD patients. The method permitted the detection of an increase in LCA wall echographic density which was typical of arterial atherosclerosis, and the assessment of a degree of arterial wall atherosclerotic density.
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PMID:[The left coronary artery in ischemic heart disease patients (data from 2-dimensional echocardiography)]. 342 88

Phosphocreatine (Neoton produced by "Schapparelli Farmaceutici") was infused intravenously to 27 patients with CHD at a dose of 2000 mg: 13 patients with unstable and 10 patients with stable angina pectoris. Phosphocreatine blocked ADP-induced platelet aggregation in these patients, but had no significant effect on the platelet aggregation induced by collagen, platelet activating factor or serotonin.
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PMID:[Phosphocreatine: thrombocyte aggregation in patients with stenocardia]. 342 17

It was established that the use of thymalin in multimodality therapy of CHD patients suffering from attacks of angina pectoris of effort and at rest brought back to normal the state of cellular and humoral immunity, slowed down blood coagulation, decreased fibrinogen and FDP concentration, enhanced total euglobulin and Hageman-dependent fibrinolysis. A more rapid disappearance of the pain syndrome was noted in these patients as compared to those who had not received the drug.
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PMID:[Effect of thymalin on the status of immunogenesis and hemostasis in patients with ischemic heart disease]. 348 3

Type A behavior was assessed in Rotterdam in 3171 males, aged 45-59 years, by the Jenkins Activity Survey (JAS) as part of the Kaunas-Rotterdam Intervention Study (KRIS). During a follow-up period of 9 1/2 years, 112 fatal and 157 non-fatal cases of myocardial infarction occurred. The JAS did not predict future cases of fatal or non-fatal myocardial infarction. Persons scoring highest on the hard-driving scale or the Dutch adaptation of the JAS tended to have higher incidences of angina pectoris. However, overall the validity of this test as a predictor of CHD was not substantiated in this population.
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PMID:A prospective study of the Jenkins Activity Survey as a risk indicator for coronary heart disease in the Netherlands. 361 Dec 94

A total of 32 CHD patients with angina pectoris of effort, functional class I-IV, aged 46 to 68 were examined. Eight patients with cervical osteochondrosis of the same age were controls. In CHD patients with angina pectoris, functional class I-II, the content of leu-enkephalin in the blood plasma did not differ from that in the control group whereas in patients with angina pectoris, functional class II-IV, it was lowered by 42%. In CHD patients aged 46 to 55 the level of leu-enkephalin in the blood plasma was raised, in the group of patients aged 55 to 68 it was considerably lowered.
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PMID:[Leu-enkephalin levels in the blood of patients with ischemic heart disease]. 373 88

Pretest probability of coronary heart disease should be considered in interpreting exercise test results. In general, 90% of patients with typical angina pectoris, 50% of patients with atypical angina pectoris, and only 10% of patients with nonanginal chest pains have CHD. Marked ST-segment depression in multiple leads is a good indication of extensive coronary artery disease, especially when it occurs early during exercise or at submaximal exercise, and if associated with a blunted or a hypotensive BP response.
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PMID:Angina: DDx of atypical presentations in the elderly. 375 81


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