Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002962 (angina)
 21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinico-metabolic and anti-ischemic effects of lisinopril and its influence on processes of left ventricular remodeling were studied on 64 patients with ischemic heart disease and stable class II-III effort angina combined with type 2 diabetes mellitus; 30 patients received standard therapy, 34--standard therapy plus lisinopril (5 mg/day). Investigation included Holter ECG monitoring, echocardiography, assessment of carbohydrate and lipid profile at baseline, in 1 and 3 months. Lisinopril exerted anti-ischemic effect, improved systolic and diastolic cardiac function, facilitated regression of left ventricular hypertrophy, and favorably affected carbohydrate and lipid metabolism at the background of body mass decrease. Lisinopril was well tolerated by patients.
 ...
PMID:[Clinico-metabolic and anti-ischemic effects of angiotensin converting enzyme inhibitor lisinopril and its role in the process of left ventricular remodeling in patients with diabetic heart]. 1704 17