Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002962 (angina)
21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a group of 53 subjects (prevalence of the disease = 91%), the sensitivity of stress myocardial scintigraphy is lower (66%); the predictive value of a negative SMS is only 28 per cent: these results can be explained by the clinical profile of the subjects included in this group (men with an average age of 50 with typical effort angina), but also by the high incidence of one vessel stenoses of the right coronary artery or the circumflex artery (19/35) which are less accessible to SMS. For the series as a whole, the combination of the two tests provided optimal results: double positivity (SMS+/stress ECG+) has a predictive value of 97 per cent; double negativity (SMS-/SE-) corresponds to 83 per cent true negatives. Furthermore, the combination of SMS+/SE+ is suggestive of more severe coronary disease (defined by the presence of a tight stenosis of the IVA or multi-vessel disease). Such severe disease is encountered in less than 7 per cent of cases when the two tests are negative.
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PMID:[Exercise myocardial scintigraphy for the positive and topographic diagnosis of coronary disease. Study in 115 patients without antecedents of myocardial infarction]. 671 31