Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002962 (angina)
 21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A study was made of exercise tolerance and indices of central hemodynamics in 151 patients with "isolated" angina and its combination with cardialgia, arterial hypertension and postinfarctional cardiosclerosis. Daily attacks of angina of effort (III functional class) were noted in all the patients. In patients with "isolated" angina and angina in postinfarctional cardiosclerosis exercise tolerance was the lowest. It was the highest in angina combined with cardialgia. The lowest indices of cardiac output were observed in patients with "isolated" angina and angina in postinfarctional cardiosclerosis. The best effect of nitrate therapy was obtained in patients with typical angina.
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PMID:[Clinico-functional characteristics of stenocardia and the effectiveness of its treatment with nitrong and erinit]. 309 Jul 30

One hundred and thirty-six patients with CHD were examined by plane scintigraphy and single-photon emission computer-aided tomography (SPECT). The control group comprised 26 healthy persons. Two SPECT techniques were compared (gamma-chamber rotation at 360 and 180 degrees). In acute myocardial infarction, focal defects of perfusion were detected by SPECT in 36 out of 39 patients, those by plane scintigraphy in 30 patients. In angina pectoris patients, perfusion alterations were detected by SPECT and scintigraphy in 91.6 and 75% of cases, respectively. During tomographic examination of patients with postinfarction cardiosclerosis, the perfusion defects were revealed in 38 out of 42 patients, whereas during plane scintigraphy, such alterations were detected but in 31 patients. The advantages of SPECT and its high importance for diagnosing different patterns of CHD are discussed. It is recommended that SPECT and plane scintigraphy can be used combined in clinical practice.
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PMID:[Single-photon emission computed tomography with 201Tl in the diagnosis of ischemic heart disease]. 387 44

Coronary heart disease (CHD) was followed up in 239 patients with rheumatic heart disease. According to the clinical data 40 (16.73%) patients had myocardial infarction (MI), 100 (41.84%) cardiosclerosis (CS), 185 (77.4%) angina pectoris (AP). AP (44.35%) prevailed among the isolated (66.1%) forms of valvular disease, associated AP and CS (23%) among the combined (33.9%) forms. In the majority of patients, AP originated and ran its course as stable throughout many years; in one-fifth of patients, the disease occurred as unstable. The incidence of AP was significantly higher in the senior age group, in women with aortic valvular disease, in men with stage III circulatory failure, and in cardiomegaly, AP aggravated the disease and life prognosis. MI was manifested by a moderately pronounced painful attack; it was frequently complicated by acute or incremental chronic circulatory failure. Small-focal MI was seen more frequently while the electrocardiographic changes associated with the disease resembled those seen in rheumatic carditis. Postinfarction CS stimulated the onset and progress of chronic congestive heart failure in 93.02% of patients.
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PMID:[The course of ischemic heart disease in rheumatic defects in persons over 45]. 401 13

A total of 202 patients with coronary heart disease and 115 patients with hypertension were examined to study their specific and frustration characteristics. Isenk's questionnaire and Rosentsveig's test were used. In CHD and postinfarction cardiosclerosis extraversion prevailed, in hypertension intraversion was more common. The indicator of neuroticism was high among all the patients under study. The choleric temperament prevailed in angina pectoris. Choleric and melancholic peculiarities were typical of patients with postinfarction cardiosclerosis and hypertension. Extrapunitive reactions were clearly revealed by Rosenzweig's test in all the study groups.
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PMID:[Character peculiarities in patients with various forms of ischemic heart disease and hypertension]. 408 82

The paper is concerned with evaluation of myocardial function in men under 50 without the clinical manifestations of coronary heart disease (CHD), in patients with angina pectoris and postinfarction cardiosclerosis. The examinees were divided into groups with and without hyperlipidemia (HLP). The cholesterol level not less than 300 mg/100 ml (7.76 mmol/l) and the triglyceride level not less than 200 mg/100 ml (2.25 mmol/l) was regarded as hyperlipidemic. To judge myocardial function, use was made of the criterion of exercise tolerance on a treadmill and of polycardiography (PCG) and apical cardiography (ACG). It was established that in groups with HLP, the exercise tolerance was lower than in analogous clinical groups without HLP. PCG and ACG were also helpful in a more frequent detection of cardiodynamic disorders in HLP groups. The exercise test has shown that in HLP, the ischemic responses in CHD patients occur more readily and more frequently. Possible mechanisms of an adverse effect of HLP are discussed.
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PMID:[Role of hyperlipidemia in disorders of myocardial function in men with or without angina pectoris and post-infarction cardiosclerosis]. 652 1

An experimental study in white mice infected with influenza virus A1, staphylococcus, Pseudomonas aeruginosa, Escherichia coli or Proteus, showed toxic vascular, stromal and cardiomyocyte damage in the myocardium within the first 2-3 days (circulation disorders, edema, dystrophic and necrotic changes in cardiomyocytes), which by day 3-5 were replaced by inflammation resulting in the formation of myocarditic cardiosclerosis foci by the 3d-4th week. Certain immune disorders were detected in patients with infectious myocarditis; cardiac antigen was found in the serum of 24%, anticardiac antibodies in 22%, positive blast transformation tests in 7.5%, as well as reduced quantities of T cells. Coons's method at late dates after staphylococcal angina revealed antibodies to myocardial structures in 45.7% of patients, and those to connective tissue in 36.1-31.4%. Myocarditis signs were identified in part of those. A scheme is proposed for the pathogenesis of infectious myocarditis.
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PMID:[Patho- and morphogenesis of infectious myocarditis]. 664 66

Immunologic shifts and indices of nonspecific reactivity were examined in 261 coronary heart disease patients (40 patients with angina pectoris, 137 with acute myocardial infarction and 124 patients with postinfarctional cardiosclerosis). Cell-mediated and humoral immune responses to the infarctional antigen affecting the prognosis and the clinical course of the disease were determined in the acute, subacute and long-term periods of coronary pathology. Autoimmune reactions to the myocardial innate antigen can be detected at all stages of coronary heart disease. Myocardial infarction is also characterized by dysfunctions of individual links of nonspecific reactivity.
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PMID:[Immunologic shifts at different stages of coronary disease]. 671 86

The immediate and late results of Weinberg's operation have been studied in 56 patients with chronic ischaemic heart disease (CIHD) with diffuse coronary sclerosis. Two control groups were compared; those with CIHD who were not operated on, and those who were subjected to pericardocardiopexy. The follow-up periods lasted from 6 months to 10 years. It was established that Weinberg's operation produced good effect in 76% of patients with chronic ischaemic heart disease. The operation is indicated in angina refractory to conservative therapy, with diffuse atherosclerotic lesions of the coronary bed, confirmed angiographically. Concomitant hypertensive disease, obesity, marked cardiosclerosis, recent myocardial infarction decrease the efficacy of Weinberg's operation.
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PMID:[Immediate and late results of Vineberg's operation in chronic ischemic heart disease with diffuse coronary arteriosclerosis]. 712 Jul 35

Echocardiography was conducted in 169 patients with ischemic heart disease (atherosclerotic and postinfarction cardiosclerosis, angina pectoris, unstable angina pectoris, myocardial infarction) to determine the diagnostic importance of changes in the contractile function of the interventricular septum (IVS). It is shown that no essential changes in IVS contractility detectable by echocardiography are encountered in patients with ischemic heart disease in a period clear of exacerbation. During an attack of angina pectoris, a decrease of the mean normalized rate of IVS systolic displacement is recorded, which suggests indirectly a lesion of the left anterior descending artery. IVS contractile function increases in the pre-infarction period, which is a compensatory reaction to the changes in the contractile function of the left ventricle.
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PMID:[Diagnostic significance of a change in the contractile function of the interventricular septum in ischemic heart disease (based on echocardiographic data)]. 737 1

The work deals with the comparative study of the tolerance of 80 patients with post-infarction cardiosclerosis with a different clinical picture of the disease to isometric and dynamic loads. It was established that the strength of the hands was weaker in patients with the cardiac pain syndrome than in healthy individuals. In addition to this in patients with cardialgia, the tolerance to isometric load was diminished. In isometric loading the systolic arterial pressure in all patients increases much more than in individuals of the control group, and in patients with severe post-infarction angina pectoris there are also changes in the pulse. Cardialgia has a determining effect on the tolerance to isometric load, whereas the dynamic test tolerance is mainly limited by the severity of chronic coronary insufficiency.
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PMID:[Isometric load tolerance in patients with postinfarct cardiosclerosis]. 739 11


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