Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002962 (angina)
 21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An attempt has been made to characterize so-called "responders" to cold among patients with effort angina. Forty-nine such patients, unselected with regard to their history of reactions to cold, who showed ST depressions during and after exercise, were examined. They worked on a bicycle ergometer close to their maximum capacity, Wmax, at room temperature (about 23 degrees C) and in a cold room (-15 degrees C). ECG was recorded and a rating scale was used to estimate the perceived exertion during exercise (RPE). The presence of angina pectoris during exercise and its duration after exercise was recorded by an EA score. An EA/W index was used to estimate the severity of the effort angina. In the whole group, the mean Wmax decreased and the mean ST depressions, RPE, and EA/W index (but not EA score) increased on exposure to cold. The changes in these variables due to exposure to cold were all associated (but not the EA score). Criteria requiring a decrease in Wmax or increase in ST depression, RPE or EA/W index on cold exposure identified 53 to 63 percent of the patients. By combining the criteria, the number of patients, who were identified, decreased. If all the criteria were applied, about 30 percent of the patients were identified as "responders" to cold and they showed the most marked responses. Thus several exercise ECG test parameters may be used to reliably define "responders" to cold exposure. This may enhance future studies of the response reaction.
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PMID:Reaction of patients with effort angina to cold exposure during exercise. 136 14

We sought to describe the differences in exercise prescription in obese subjects using attained METs as compared to the subjective perception of the effort using the Borg scale ratings of perceived exertion (Borg RPE). We studied 552 obese patients who underwent an exercise stress test in the setting of a rehabilitation program. Exercise was prescribed at 70% of peak attained METS. This method was compared to an exercise level prescription that induces a subjective perception of mild fatigue (13 on the 20 points Borg scale). Attained METS were 6.2+/-2.5 and Borg RPE was 15.2+/-1.7. Borg RPE was negatively related to intensity and duration of exercise. Females, patient with a lower level of education and patients on diuretics perceived higher efforts. Patients who stopped exercising because of dyspnea or angina reached a lower level of METs (4.7+/-1.7 vs 6.3+/-2.7 METs; P<0.001) but the perceived effort was similar (15.5+/-1.7 vs 15.2+/-1.7; P=0.252). The subjective method would have yielded a significantly higher training workload: 5.4+/-2.3 vs 4.3+/-1.8 (P<0.001). In conclusion, in obese patients, Borg RPE is not equivalent to attained METs in exercise prescription and it influenced by educational level.
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PMID:What are we measuring? Considerations on subjective ratings of perceived exertion in obese patients for exercise prescription in cardiac rehabilitation programs. 1906 92